Structure of Chelator-GIDSR4 - Fbp1 - phospho-Ubc8~ubiquitin - class I
Chrustowicz J, Sherpa D, Li J, Langlois CR, Papadopoulou EC, Vu DT, Hehl LA, Karayel O, Beier V, von Gronau S, Muller J, Prabu JR, Mann M, Kleiger G, Alpi AF, Schulman BA
Mol Cell (2024) 84 pp. 293-308.e14 [ DOI: doi:10.1016/j.molcel.2023.11.027 Pubmed: 38113892 ]
Structure of Chelator-GIDSR4 - Fbp1 - phospho-Ubc8~ubiquitin - class II
Chrustowicz J, Sherpa D, Li J, Langlois CR, Papadopoulou EC, Vu DT, Hehl LA, Karayel O, Beier V, von Gronau S, Muller J, Prabu JR, Mann M, Kleiger G, Alpi AF, Schulman BA
Mol Cell (2024) 84 pp. 293-308.e14 [ DOI: doi:10.1016/j.molcel.2023.11.027 Pubmed: 38113892 ]
Chelator-GIDSR4 - Fbp1 - phospho-Ubc8~ubiquitin - class III
Chrustowicz J, Sherpa D, Li J, Langlois CR, Papadopoulou EC, Vu DT, Hehl LA, Karayel O, Beier V, von Gronau S, Muller J, Prabu JR, Mann M, Kleiger G, Alpi AF, Schulman BA
Mol Cell (2024) 84 pp. 293-308.e14 [ DOI: doi:10.1016/j.molcel.2023.11.027 Pubmed: 38113892 ]
Structure of Chelator-GIDSR4 - Fbp1 - phospho-Ubc8~ubiquitin - class V
Chrustowicz J, Sherpa D, Li J, Langlois CR, Papadopoulou EC, Vu DT, Hehl LA, Karayel O, Beier V, von Gronau S, Muller J, Prabu JR, Mann M, Kleiger G, Alpi AF, Schulman BA
Mol Cell (2024) 84 pp. 293-308.e14 [ DOI: doi:10.1016/j.molcel.2023.11.027 Pubmed: 38113892 ]
Structure of Chelator-GIDSR4 - Fbp1 - phospho-Ubc8~ubiquitin - class IV
Chrustowicz J, Sherpa D, Li J, Langlois CR, Papadopoulou EC, Vu DT, Hehl LA, Karayel O, Beier V, von Gronau S, Muller J, Prabu JR, Mann M, Kleiger G, Alpi AF, Schulman BA
Mol Cell (2024) 84 pp. 293-308.e14 [ DOI: doi:10.1016/j.molcel.2023.11.027 Pubmed: 38113892 ]
Catalytic module of human CTLH E3 ligase bound to multiphosphorylated UBE2H~ubiquitin
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8pjn
Q-score: 0.529
Chrustowicz J, Sherpa D, Li J, Langlois CR, Papadopoulou EC, Vu DT, Hehl LA, Karayel O, Beier V, von Gronau S, Muller J, Prabu JR, Mann M, Kleiger G, Alpi AF, Schulman BA
Mol Cell (2024) 84 pp. 293- [ DOI: doi:10.1016/j.molcel.2023.11.027 Pubmed: 38113892 ]
- Complex of human ctlhsr4 e3 ligase bound to engineered armc8-specific vh and multiphosphorylated ube2h~ubiquitin (600 kDa, Complex from Homo sapiens)
- Ubiquitin-conjugating enzyme e2 h (21 kDa, Protein from Homo sapiens)
- Ubiquitin (8 kDa, Protein from Homo sapiens)
- E3 ubiquitin-protein transferase rmnd5a (44 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- E3 ubiquitin-protein transferase maea (45 kDa, Protein from Homo sapiens)
SRS and Cat modules of human CTLHSR4 bound to multiphosphorylated UBE2H~ubiquitin
Chrustowicz J, Sherpa D, Li J, Langlois CR, Papadopoulou EC, Vu DT, Hehl LA, Karayel O, Beier V, von Gronau S, Muller J, Prabu JR, Mann M, Kleiger G, Alpi AF, Schulman BA
Mol Cell (2024) 84 pp. 293-308.e14 [ DOI: doi:10.1016/j.molcel.2023.11.027 Pubmed: 38113892 ]
Structure of CTLHSR4 - phospho-UBE2H~ubiquitin bound to engineered VH
Chrustowicz J, Sherpa D, Li J, Langlois CR, Papadopoulou EC, Vu DT, Hehl LA, Karayel O, Beier V, von Gronau S, Muller J, Prabu JR, Mann M, Kleiger G, Alpi AF, Schulman BA
Mol Cell (2024) 84 pp. 293-308.e14 [ DOI: doi:10.1016/j.molcel.2023.11.027 Pubmed: 38113892 ]
SRS and Cat modules of yeast Chelator-GIDSR4 bound to multiphosphorylated Ubc8~ubiquitin
Chrustowicz J, Sherpa D, Li J, Langlois CR, Papadopoulou EC, Vu DT, Hehl LA, Karayel O, Beier V, von Gronau S, Muller J, Prabu JR, Mann M, Kleiger G, Alpi AF, Schulman BA
Mol Cell (2024) 84 pp. 293-308.e14 [ DOI: doi:10.1016/j.molcel.2023.11.027 Pubmed: 38113892 ]
Catalytic module of yeast GID E3 ligase bound to multiphosphorylated Ubc8~ubiquitin
Resolution: 3.53 Å
EM Method: Single-particle
Fitted PDBs: 8pmq
Q-score: 0.514
Chrustowicz J, Sherpa D, Li J, Langlois CR, Papadopoulou EC, Vu DT, Hehl LA, Karayel O, Beier V, von Gronau S, Muller J, Prabu JR, Mann M, Kleiger G, Alpi AF, Schulman BA
Mol Cell (2024) 84 pp. 293- [ DOI: doi:10.1016/j.molcel.2023.11.027 Pubmed: 38113892 ]
- Protein fyv10 (59 kDa, Protein from Saccharomyces cerevisiae)
- Ubiquitin (8 kDa, Protein from Homo sapiens)
- Ubiquitin-conjugating enzyme e2-24 kda (24 kDa, Protein from Saccharomyces cerevisiae)
- Complex of yeast chelator-gidsr4 e3 ligase, tetrameric fbp1 substrate and multiphosphorylated ubc8~ubiquitin (1 MDa, Complex from Saccharomyces cerevisiae)
- E3 ubiquitin-protein ligase rmd5 (49 kDa, Protein from Saccharomyces cerevisiae)
- Zinc ion (65 Da, Ligand)