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primary_citation_author:"Li J" AND author_orcid:"0000-0002-0071-6792" AND xref_links:"interpro"
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PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state

Release date: Nov. 2, 2022
Resolution: 5.04 Å
EM Method: Single-particle
Fitted PDBs: 8gxq
Q-score: 0.084

Chen X, Wang X, Liu W, Ren Y, Qu X, Li J, Yin X, Xu Y

Science (2022) 378 pp. 62-68 [ DOI: doi:10.1126/science.abn8131 Pubmed: 36201575 ]

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PIC-Mediator in complex with +1 nucleosome (T40N) in H-binding state

Release date: Nov. 2, 2022
Resolution: 4.16 Å
EM Method: Single-particle
Fitted PDBs: 8gxs
Q-score: 0.093

Chen X, Wang X, Liu W, Ren Y, Qu X, Li J, Yin X, Xu Y

Science (2022) 378 pp. 62-68 [ DOI: doi:10.1126/science.abn8131 Pubmed: 36201575 ]

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TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED)

Release date: May 26, 2021
Resolution: 4.07 Å
EM Method: Single-particle
Fitted PDBs: 7ena
Q-score: 0.168

Chen X, Yin X, Li J, Wu Z, Qi Y, Wang X, Liu W, Xu Y

Science (2021) 372 [ Pubmed: 33958484 DOI: doi:10.1126/science.abg0635 ]

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TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED)

Release date: May 26, 2021
Resolution: 4.13 Å
EM Method: Single-particle
Fitted PDBs: 7enc
Q-score: 0.103

Chen X, Yin X, Li J, Wu Z, Qi Y, Wang X, Liu W, Xu Y

Science (2021) 372 [ Pubmed: 33958484 DOI: doi:10.1126/science.abg0635 ]

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Human Mediator (deletion of MED1-IDR) in a Tail-bent conformation (MED-B)

Release date: May 19, 2021
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 7enj
Q-score: 0.17

Chen X, Yin X, Li J, Wu Z, Qi Y, Wang X, Liu W, Xu Y

Science (2021) 372 [ Pubmed: 33958484 DOI: doi:10.1126/science.abg0635 ]

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p53-bound TFIID-based holo PIC on HDM2 promoter

Release date: May 12, 2021
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7egc
Q-score: 0.051

Chen X, Qi Y, Wu Z, Wang X, Li J, Zhao D, Hou H, Li Y, Yu Z, Liu W, Wang M, Ren Y, Li Z, Yang H, Xu Y

Science (2021) 372 [ Pubmed: 33795473 DOI: doi:10.1126/science.aba8490 ]

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SCP promoter-bound TFIID-TFIIA in initial TBP-loading state

Release date: May 12, 2021
Resolution: 6.75 Å
EM Method: Single-particle
Fitted PDBs: 7egd
Q-score: 0.099

Chen X, Qi Y, Wu Z, Wang X, Li J, Zhao D, Hou H, Li Y, Yu Z, Liu W, Wang M, Ren Y, Li Z, Yang H, Xu Y

Science (2021) 372 [ Pubmed: 33795473 DOI: doi:10.1126/science.aba8490 ]

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TFIID in canonical conformation

Release date: May 12, 2021
Resolution: 9.0 Å
EM Method: Single-particle
Fitted PDBs: 7ege
Q-score: 0.078

TFIID in rearranged conformation

Release date: May 12, 2021
Resolution: 9.82 Å
EM Method: Single-particle
Fitted PDBs: 7egi
Q-score: 0.079

Chen X, Qi Y, Wu Z, Wang X, Li J, Zhao D, Hou H, Li Y, Yu Z, Liu W, Wang M, Ren Y, Li Z, Yang H, Xu Y

Science (2021) 372 [ Pubmed: 33795473 DOI: doi:10.1126/science.aba8490 ]

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