Cryo-EM structure of long form insulin receptor (IR-B) in the apo state
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8u4b
Q-score: 0.388
An W, Hall C, Li J, Hung A, Wu J, Park J, Wang L, Bai XC, Choi E
Nat Commun (2024) 15 pp. 2609-2609 [ Pubmed: 38521788 DOI: doi:10.1038/s41467-024-46990-6 ]
- Insulin receptor (156 kDa, Protein from Homo sapiens)
- Long form insulin receptor in the apo state (Complex from Homo sapiens)
Cryo-EM structure of long form insulin receptor (IR-B) with four IGF2 bound, symmetric conformation.
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8u4c
Q-score: 0.359
An W, Hall C, Li J, Hung A, Wu J, Park J, Wang L, Bai XC, Choi E
Nat Commun (2024) 15 pp. 2609-2609 [ Pubmed: 38521788 DOI: doi:10.1038/s41467-024-46990-6 ]
- Insulin receptor (156 kDa, Protein from Homo sapiens)
- Insulin-like growth factor ii (20 kDa, Protein from Homo sapiens)
- Long form insulin receptor (ir-b) with four igf2 bound, symmetric conformation. (Complex from Homo sapiens)
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 8u4e
Q-score: 0.279
An W, Hall C, Li J, Hung A, Wu J, Park J, Wang L, Bai XC, Choi E
Nat Commun (2024) 15 pp. 2609-2609 [ Pubmed: 38521788 DOI: doi:10.1038/s41467-024-46990-6 ]
- Long form insulin receptor (ir-b) with three igf2 bound, asymmetric conformation. (Complex from Homo sapiens)
- Insulin-like growth factor ii (20 kDa, Protein from Homo sapiens)
- Insulin receptor (156 kDa, Protein from Homo sapiens)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7tyj
Q-score: 0.528
Wang L, Hall C, Li J, Choi E, Bai XC
Nat Struct Mol Biol (2023) 30 pp. 661-669 [ DOI: doi:10.1038/s41594-023-00974-0 Pubmed: 37055497 ]
- Insulin receptor-related receptor (irr) in apo-state captured at ph 7 (140 kDa, Complex from Homo sapiens)
- Insulin receptor-related protein (143 kDa, Protein from Homo sapiens)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7tyk
Q-score: 0.479
Wang L, Hall C, Li J, Choi E, Bai XC
Nat Struct Mol Biol (2023) 30 pp. 661-669 [ DOI: doi:10.1038/s41594-023-00974-0 Pubmed: 37055497 ]
- Insulin receptor-related receptor (irr) in apo-state captured at ph 7 (140 kDa, Complex from Homo sapiens)
- Insulin receptor-related protein (143 kDa, Protein from Homo sapiens)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7tym
Q-score: 0.492
Wang L, Hall C, Li J, Choi E, Bai XC
Nat Struct Mol Biol (2023) 30 pp. 661-669 [ DOI: doi:10.1038/s41594-023-00974-0 Pubmed: 37055497 ]
- Insulin receptor-related protein (143 kDa, Protein from Homo sapiens)
- Insulin receptor-related receptor (irr) in active-state captured at ph 9 (140 kDa, Complex from Homo sapiens)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 8eyr
Q-score: 0.346
Li J, Wu J, Hall C, Bai XC, Choi E
eLife (2022) 11 [ DOI: doi:10.7554/eLife.81286 Pubmed: 36413010 ]
- Insulin-like growth factor 1 receptor (144 kDa, Protein from Mus musculus)
- Two igf1 bound full-length mouse igf1r mutant (four glycine residues inserted in the alpha-ct; igf1r-p674g4): symmetric conformation (Complex from Mus musculus)
- Insulin-like growth factor i (21 kDa, Protein from Homo sapiens)
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 8eyx
Q-score: 0.237