Structure of human SCMC ternary complex
Resolution: 3.01 Å
EM Method: Single-particle
Fitted PDBs: 8x7v
Q-score: 0.463
Chi P, Ou G, Liu S, Ma Q, Lu Y, Li J, Li J, Qi Q, Han Z, Zhang Z, Liu Q, Guo L, Chen J, Wang X, Huang W, Li L, Deng D
Nat Struct Mol Biol (2024) 31 pp. 1798-1807 [ DOI: doi:10.1038/s41594-024-01396-2 Pubmed: 39379527 ]
- Oocyte-expressed protein homolog (18 kDa, Protein from Homo sapiens)
- Ubiquitin-like protein smt3,transducin-like enhancer protein 6 (59 kDa, Protein from Homo sapiens)
- Maltose/maltodextrin-binding periplasmic protein,nacht, lrr and pyd domains-containing protein 5 (171 kDa, Protein from Homo sapiens)
- Human scmc ternary complex (Complex from Homo sapiens)
Structure of dimeric human SCMC complex
Resolution: 3.36 Å
EM Method: Single-particle
Fitted PDBs: 8x7w
Q-score: 0.356
Chi P, Ou G, Liu S, Ma Q, Lu Y, Li J, Li J, Qi Q, Han Z, Zhang Z, Liu Q, Guo L, Chen J, Wang X, Huang W, Li L, Deng D
Nat Struct Mol Biol (2024) 31 pp. 1798-1807 [ DOI: doi:10.1038/s41594-024-01396-2 Pubmed: 39379527 ]
- Oocyte-expressed protein homolog (18 kDa, Protein from Homo sapiens)
- Ubiquitin-like protein smt3,transducin-like enhancer protein 6 (59 kDa, Protein from Homo sapiens)
- Maltose/maltodextrin-binding periplasmic protein,nacht, lrr and pyd domains-containing protein 5 (171 kDa, Protein from Homo sapiens)
- Human scmc complex (Complex from Homo sapiens)
Resolution: 3.81 Å
EM Method: Single-particle
Fitted PDBs: 8h8e
Q-score: 0.368
Structure of Xenopus tropicalis acid-sensitive outwardly rectifying channel ASOR (resting state)
Resolution: 3.48 Å
EM Method: Single-particle
Fitted PDBs: 8h8f
Q-score: 0.391
Structure of dimeric mouse SCMC core complex
Resolution: 3.01 Å
EM Method: Single-particle
Fitted PDBs: 8h93
Q-score: 0.398
Chi P, Ou G, Qin D, Han Z, Li J, Xiao Q, Gao Z, Xu C, Qi Q, Liu Q, Liu S, Li J, Guo L, Lu Y, Chen J, Wang X, Shi H, Li L, Deng D
Nat Struct Mol Biol (2024) 31 pp. 115-124 [ Pubmed: 38177687 DOI: doi:10.1038/s41594-023-01153-x ]
- The mouse subcortical maternal complex (Complex from Mus musculus)
- Nacht, lrr and pyd domains-containing protein 5 (119 kDa, Protein from Mus musculus)
- Transducin-like enhancer protein 6 (65 kDa, Protein from Mus musculus)
- Oocyte-expressed protein homolog (18 kDa, Protein from Mus musculus)
Structure of mouse SCMC bound with full-length FILIA
Resolution: 3.38 Å
EM Method: Single-particle
Fitted PDBs: 8h95
Q-score: 0.445
Chi P, Ou G, Qin D, Han Z, Li J, Xiao Q, Gao Z, Xu C, Qi Q, Liu Q, Liu S, Li J, Guo L, Lu Y, Chen J, Wang X, Shi H, Li L, Deng D
Nat Struct Mol Biol (2024) 31 pp. 115-124 [ Pubmed: 38177687 DOI: doi:10.1038/s41594-023-01153-x ]
- Transducin-like enhancer protein 6 (65 kDa, Protein from Mus musculus)
- Nacht, lrr and pyd domains-containing protein 5 (119 kDa, Protein from Mus musculus)
- Structure of mouse scmc bound with full-length filia (Complex from Mus musculus)
- Oocyte-expressed protein homolog (18 kDa, Protein from Mus musculus)
Full-length insulin receptor bound with site 1 binding deficient mutant insulin (A-V3E)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7sl1
Q-score: 0.433
Li J, Park J, Mayer JP, Webb KJ, Uchikawa E, Wu J, Liu S, Zhang X, Stowell MHB, Choi E, Bai XC
Nat Struct Mol Biol (2022) 29 pp. 357-368 [ Pubmed: 35361965 DOI: doi:10.1038/s41594-022-00750-6 ]
- Insulin receptor (155 kDa, Protein from Mus musculus)
- Insulin a chain (2 kDa, Protein from Homo sapiens)
- Insulin b chain (3 kDa, Protein from Homo sapiens)
- Full-length insulin receptor bound with site 1 binding deficient mutant insulin (a-v3e) (Complex)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7sl2
Q-score: 0.39
Li J, Park J, Mayer JP, Webb KJ, Uchikawa E, Wu J, Liu S, Zhang X, Stowell MHB, Choi E, Bai XC
Nat Struct Mol Biol (2022) 29 pp. 357-368 [ Pubmed: 35361965 DOI: doi:10.1038/s41594-022-00750-6 ]
- Insulin receptor (155 kDa, Protein from Mus musculus)
- Insulin a chain (2 kDa, Protein from Homo sapiens)
- Full-length insulin receptor bound with site 2 binding deficient mutant insulin (a-l13r) -- asymmetric conformation (Complex)
- Insulin b chain (3 kDa, Protein from Homo sapiens)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7sl3
Q-score: 0.417
Li J, Park J, Mayer JP, Webb KJ, Uchikawa E, Wu J, Liu S, Zhang X, Stowell MHB, Choi E, Bai XC
Nat Struct Mol Biol (2022) 29 pp. 357-368 [ Pubmed: 35361965 DOI: doi:10.1038/s41594-022-00750-6 ]
- Insulin receptor (155 kDa, Protein from Mus musculus)
- Insulin a chain (2 kDa, Protein from Homo sapiens)
- Insulin b chain (3 kDa, Protein from Homo sapiens)
- Full-length insulin receptor bound with site 2 binding deficient mutant insulin (a-l13r) -- symmetric conformation (Complex)
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7sl6
Q-score: 0.39
Li J, Park J, Mayer JP, Webb KJ, Uchikawa E, Wu J, Liu S, Zhang X, Stowell MHB, Choi E, Bai XC
Nat Struct Mol Biol (2022) 29 pp. 357-368 [ Pubmed: 35361965 DOI: doi:10.1038/s41594-022-00750-6 ]
- Insulin receptor (155 kDa, Protein from Mus musculus)
- Insulin b chain (3 kDa, Protein from Homo sapiens)
- Full-length insulin receptor bound with site 2 binding deficient mutant insulin (b-l17r) -- symmetric conformation (Complex)
- Insulin a chain (2 kDa, Protein from Homo sapiens)