Resolution: 3.81 Å
EM Method: Single-particle
Fitted PDBs: 8h8e
Q-score: 0.368
Structure of Xenopus tropicalis acid-sensitive outwardly rectifying channel ASOR (resting state)
Resolution: 3.48 Å
EM Method: Single-particle
Fitted PDBs: 8h8f
Q-score: 0.391
Human TWIK-related acid-sensitive potassium channel TASK3 at pH 7.4,200 mM KCl
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8k1j
Q-score: 0.489
Lin H, Li J, Zhang Q, Yang H, Chen S
PNAS (2024) 121 pp. e2320345121-e2320345121 [ DOI: doi:10.1073/pnas.2320345121 Pubmed: 38630723 ]
- Water (18 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Potassium channel subfamily k member 9 (31 kDa, Protein from Homo sapiens)
- Chs (Complex from Homo sapiens)
Human TWIK-related acid-sensitive potassium channel TASK3 at pH 6.0, 5 mM KCl and 135 mM NaCl
Resolution: 3.68 Å
EM Method: Single-particle
Fitted PDBs: 8k1q
Q-score: 0.41
Lin H, Li J, Zhang Q, Yang H, Chen S
PNAS (2024) 121 pp. e2320345121-e2320345121 [ DOI: doi:10.1073/pnas.2320345121 Pubmed: 38630723 ]
- Water (18 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Potassium channel subfamily k member 9 (31 kDa, Protein from Homo sapiens)
- Chs (Complex from Homo sapiens)
Human TWIK-related acid-sensitive potassium channel TASK3 at pH 7.4, 5 mM KCl and 135 mM NaCl
Resolution: 3.48 Å
EM Method: Single-particle
Fitted PDBs: 8k1v
Q-score: 0.422
Lin H, Li J, Zhang Q, Yang H, Chen S
PNAS (2024) 121 pp. e2320345121-e2320345121 [ DOI: doi:10.1073/pnas.2320345121 Pubmed: 38630723 ]
- Water (18 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Potassium channel subfamily k member 9 (31 kDa, Protein from Homo sapiens)
- Chs (Complex from Homo sapiens)
Human TWIK-related acid-sensitive potassium channel TASK3 at pH 6.0, 200 mM KCl
Resolution: 3.41 Å
EM Method: Single-particle
Fitted PDBs: 8k1z
Q-score: 0.42
Lin H, Li J, Zhang Q, Yang H, Chen S
PNAS (2024) 121 pp. e2320345121-e2320345121 [ DOI: doi:10.1073/pnas.2320345121 Pubmed: 38630723 ]
- Water (18 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Potassium channel subfamily k member 9 (31 kDa, Protein from Homo sapiens)
- Chs (Complex from Homo sapiens)
human KCNQ2-CaM-Ebio1 complex in the presence of PIP2
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8ijk
Q-score: 0.383
Zhang S, Ma D, Wang K, Li Y, Yang Z, Li X, Li J, He J, Mei L, Ye Y, Chen Z, Shen J, Hou P, Guo J, Zhang Q, Yang H
Nat Chem Biol (2024) 20 pp. 847-856 [ DOI: doi:10.1038/s41589-023-01515-y Pubmed: 38167918 ]
- Potassium voltage-gated channel subfamily kqt member 2 (73 kDa, Protein from Homo sapiens)
- Human kcnq2-cam-ebio1 complex in the presence of pip2 (Complex from Homo sapiens)
- N-(1,2-dihydroacenaphthylen-5-yl)-4-fluoranyl-benzamide (291 Da, Ligand)
- Calmodulin-1 (16 kDa, Protein from Homo sapiens)
human KCNQ2-CaM-Ebio1-S1 complex in the presence of PIP2
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8x43
Q-score: 0.328
Zhang S, Ma D, Wang K, Li Y, Yang Z, Li X, Li J, He J, Mei L, Ye Y, Chen Z, Shen J, Hou P, Guo J, Zhang Q, Yang H
Nat Chem Biol (2024) 20 pp. 847-856 [ DOI: doi:10.1038/s41589-023-01515-y Pubmed: 38167918 ]
- Potassium voltage-gated channel subfamily kqt member 2 (73 kDa, Protein from Homo sapiens)
- Human kcnq2-cam-ebio1-s1 complex in the presence of pip2 (Cellular component from Homo sapiens)
- N-(4-azanyl-1,2-dihydroacenaphthylen-5-yl)-4-fluoranyl-benzamide (306 Da, Ligand)
- Calmodulin-1 (16 kDa, Protein from Homo sapiens)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8ipq
Q-score: 0.332
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8ipr
Q-score: 0.476
Zhu C, Shi Y, Yu J, Zhao W, Li L, Liang J, Yang X, Zhang B, Zhao Y, Gao Y, Chen X, Yang X, Zhang L, Guddat LW, Liu L, Yang H, Rao Z, Li J
Protein Cell (2023) 14 pp. 919-923 [ DOI: doi:10.1093/procel/pwad022 Pubmed: 37144855 ]
- Cyddc (Complex from Mycolicibacterium smegmatis)
- Component linked with the assembly of cytochrome' abc transporter atp-binding protein cydc (51 kDa, Protein from Mycolicibacterium smegmatis)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Transmembrane atp-binding protein abc transporter cydd (53 kDa, Protein from Mycolicibacterium smegmatis)