Cryo-EM structure of the Cas9d-sgRNA complex
Resolution: 2.87 Å
EM Method: Single-particle
Fitted PDBs: 8zq9
Q-score: 0.47
To Be Published
- A protein (86 kDa, Protein from metagenome)
- Zinc ion (65 Da, Ligand)
- A protein (Complex from metagenome)
- Rna (128-mer) (51 kDa, RNA from metagenome)
CENP-A/H4 di-tetrasome assembled on alpha-satellite DNA.
Ali-Ahmad A, Mors M, Carrer M, Li X, Bilokapic S, Halic M, Cascella M, Sekulic N
bioRxiv (2025) [ Pubmed: 39803555 DOI: doi:10.1101/2024.12.31.630874 ]
- 2x(cenp-a/h4)2 di-tetrasome assembled on alpha-satellite dna. (200 MDa, Complex from Homo sapiens)
- Histone h4 (11 kDa, Protein from Homo sapiens)
- 147 bp human alpha-satellite dna (45 kDa, DNA from Homo sapiens)
- Histone h3-like centromeric protein a (15 kDa, Protein from Homo sapiens)
- 147 bp alpha-satellite dna (45 kDa, DNA from Homo sapiens)
BA.2.86 RBD protein in complex with ACE2.
Resolution: 3.29 Å
EM Method: Single-particle
Fitted PDBs: 8yzb
Q-score: 0.477
Liu Y, Zhao X, Shi J, Wang Y, Liu H, Hu YF, Hu B, Shuai H, Yuen TT, Chai Y, Liu F, Gong HR, Li J, Wang X, Jiang S, Zhang X, Zhang Y, Li X, Wang L, Hartnoll M, Zhu T, Hou Y, Huang X, Yoon C, Wang Y, He Y, Zhou M, Du L, Zhang X, Chan WM, Chen LL, Cai JP, Yuan S, Zhou J, Huang JD, Yuen KY, To KK, Chan JF, Zhang BZ, Sun L, Wang P, Chu H
Nat Commun (2024) 15 pp. 8728-8728 [ DOI: doi:10.1038/s41467-024-53033-7 Pubmed: 39379369 ]
- Angiotensin-converting enzyme 2 (85 kDa, Protein from Homo sapiens)
- Spike glycoprotein,fibritin,fusion protein (142 kDa, Protein from synthetic construct)
- Ba.2.86 rbd protein in complex with ace2 (Complex from Homo sapiens)
Structure of JN.1 RBD protein in complex with ACE2.
Resolution: 3.07 Å
EM Method: Single-particle
Fitted PDBs: 8yzd
Q-score: 0.573
Liu Y, Zhao X, Shi J, Wang Y, Liu H, Hu YF, Hu B, Shuai H, Yuen TT, Chai Y, Liu F, Gong HR, Li J, Wang X, Jiang S, Zhang X, Zhang Y, Li X, Wang L, Hartnoll M, Zhu T, Hou Y, Huang X, Yoon C, Wang Y, He Y, Zhou M, Du L, Zhang X, Chan WM, Chen LL, Cai JP, Yuan S, Zhou J, Huang JD, Yuen KY, To KK, Chan JF, Zhang BZ, Sun L, Wang P, Chu H
Nat Commun (2024) 15 pp. 8728-8728 [ DOI: doi:10.1038/s41467-024-53033-7 Pubmed: 39379369 ]
Cryo-EM Structure of MILI(K852A)-piRNA-target (26-nt)
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 9ij4
Q-score: 0.474
Li Z, Xu Q, Zhong J, Zhang Y, Zhang T, Ying X, Lu X, Li X, Wan L, Xue J, Huang J, Zhen Y, Zhang Z, Wu J, Shen EZ
Nature (2025) [ DOI: doi:10.1038/s41586-024-08438-1 Pubmed: 39814893 ]
- Rna (25-mer) (8 kDa, RNA from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Mili(k852a)-pirna-target (26-nt) (Complex from Homo sapiens)
- Rna (26-mer) (8 kDa, RNA from Homo sapiens)
- Piwi-like protein 2 (109 kDa, Protein from Mus musculus)
Resolution: 2.91 Å
EM Method: Single-particle
Fitted PDBs: 9jmz
Q-score: 0.489
Song H, Hao T, Han P, Wang H, Zhang X, Li X, Wang Y, Chen J, Li Y, Jin X, Duan X, Zhang W, Bi Y, Jin R, Sun L, Wang N, Gao GF
Cell (2025) [ Pubmed: 39848246 DOI: doi:10.1016/j.cell.2025.01.019 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Human-infecting bovine influenza h5n1 hemagglutinin complexed with avian receptor analog lsta (Complex from Influenza A virus (A/Indonesia/5/2005(H5N1)))
- N-acetyl-alpha-neuraminic acid (309 Da, Ligand)
- Hemagglutinin (57 kDa, Protein from Influenza A virus (A/Indonesia/5/2005(H5N1)))
Resolution: 2.84 Å
EM Method: Single-particle
Fitted PDBs: 9jn0
Q-score: 0.518
Cryo-EM structure of human Spns1 in complex with LPC (18:1)
Resolution: 3.22 Å
EM Method: Single-particle
Fitted PDBs: 9boi
Q-score: 0.494
Chen H, Ha HTT, Elghobashi-Meinhardt N, Le NA, Schmiege P, Nguyen LN, Li X
PNAS (2025) 122 pp. e2409596121-e2409596121 [ Pubmed: 39739806 DOI: doi:10.1073/pnas.2409596121 ]
- Mvenus,maltose/maltodextrin-binding periplasmic protein,protein spinster homolog 1,designed ankyrin repeat protein (darpin) (139 kDa, Protein from Homo sapiens)
- Human spns1 purified in the presence of extra lpc addition (Cellular component from Homo sapiens)
- (4r,7r,18z)-4,7-dihydroxy-n,n,n-trimethyl-10-oxo-3,5,9-trioxa-4-phosphaheptacos-18-en-1-aminium 4-oxide (522 Da, Ligand)
Cryo-EM structure of apo-GPR55-G13 complex
Resolution: 3.01 Å
EM Method: Single-particle
Fitted PDBs: 9iy8
Q-score: 0.452
Chang H, Li X, Shen L, Ge X, Hao S, Wu L, Liu S, Liu J, Cherezov V, Hua T
Cell Res (2025) 35 pp. 80-83 [ Pubmed: 39482405 DOI: doi:10.1038/s41422-024-01046-8 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein subunit alpha-13 (26 kDa, Protein from Homo sapiens)
- G-protein coupled receptor 55 (36 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Scfv16 (26 kDa, Protein from Homo sapiens)
- Ternary complex of gpr55 with guanine nucleotide-binding protein and nanobody (175 kDa, Complex from Homo sapiens)
Cryo-EM structure of GPR55-Fab-Nb-ONO-9710531 complex
Resolution: 3.04 Å
EM Method: Single-particle
Fitted PDBs: 9iya
Q-score: 0.415
Chang H, Li X, Shen L, Ge X, Hao S, Wu L, Liu S, Liu J, Cherezov V, Hua T
Cell Res (2025) 35 pp. 80-83 [ Pubmed: 39482405 DOI: doi:10.1038/s41422-024-01046-8 ]
- G-protein coupled receptor 55,soluble cytochrome b562 (47 kDa, Protein from Homo sapiens)
- Anti-fab nanobody (13 kDa, Protein from Homo sapiens)
- 4-(3-bromanyl-5-ethoxy-4-oxidanyl-phenyl)-~{n}-(2-methoxyphenyl)-2-methyl-5-oxidanylidene-4,6,7,8-tetrahydro-1~{h}-quinoline-3-carboxamide (527 Da, Ligand)
- Ternary complex of gpr55 with anti-bril fab and anti-fab nanobody (173 kDa, Complex from Homo sapiens)
- Anti-bril fab heavy chain (26 kDa, Protein from Homo sapiens)
- Anti-bril fab light chain (23 kDa, Protein from Homo sapiens)