Cryo-EM structure of SARS-CoV-2 Omicron BA.1 spike protein in complex with mouse ACE2
Resolution: 2.66 Å
EM Method: Single-particle
Fitted PDBs: 7wrh
Q-score: 0.468
Li L, Han P, Huang B, Xie Y, Li W, Zhang D, Han P, Xu Z, Bai B, Zhou J, Kang X, Li X, Zheng A, Zhang R, Qiao S, Zhao X, Qi J, Wang Q, Liu K, Gao GF
Cell Discov (2022) 8 pp. 65-65 [ Pubmed: 35821014 DOI: doi:10.1038/s41421-022-00431-0 ]
- Processed angiotensin-converting enzyme 2 (69 kDa, Protein from Homo sapiens)
- Complex of sars-cov-2 omicron ba.1 spike protein with mouse ace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Mouse ace2 (Complex)
- Spike glycoprotein (138 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 omicron ba.1 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 7x10
Q-score: 0.465
Qian Y, Ma Z, Liu C, Li X, Zhu X, Wang N, Xu Z, Xia R, Liang J, Duan Y, Yin H, Xiong Y, Zhang A, Guo C, Chen Z, Huang Z, He Y
Mol Cell (2022) 82 pp. 4340-4352.e6 [ Pubmed: 36309016 DOI: doi:10.1016/j.molcel.2022.10.009 ]
- Gpcr/g-protein complex (Complex from Homo sapiens)
- Scfv16 (26 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Isoform 3 of adhesion g protein-coupled receptor l3 (172 kDa, Protein from Mus musculus)
- Engineered g alpha 12 subunit (39 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
Resolution: 2.83 Å
EM Method: Single-particle
Fitted PDBs: 7wy5
Q-score: 0.514
Qian Y, Ma Z, Liu C, Li X, Zhu X, Wang N, Xu Z, Xia R, Liang J, Duan Y, Yin H, Xiong Y, Zhang A, Guo C, Chen Z, Huang Z, He Y
Mol Cell (2022) 82 pp. 4340-4352.e6 [ Pubmed: 36309016 DOI: doi:10.1016/j.molcel.2022.10.009 ]
- Nb35 (17 kDa, Protein from Homo sapiens)
- Gpcr/g-protein complex (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Isoform 3 of adhesion g protein-coupled receptor l3 (172 kDa, Protein from Mus musculus)
- Engineered mini g alpha q subunit (41 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
Resolution: 2.83 Å
EM Method: Single-particle
Fitted PDBs: 7wy8
Q-score: 0.504
Qian Y, Ma Z, Liu C, Li X, Zhu X, Wang N, Xu Z, Xia R, Liang J, Duan Y, Yin H, Xiong Y, Zhang A, Guo C, Chen Z, Huang Z, He Y
Mol Cell (2022) 82 pp. 4340-4352.e6 [ Pubmed: 36309016 DOI: doi:10.1016/j.molcel.2022.10.009 ]
- Gpcr/g-protein complex (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Isoform 3 of adhesion g protein-coupled receptor l3 (172 kDa, Protein from Mus musculus)
- Gpcr/g-protein (Complex from Lama glama)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Nb35 (Complex)
- Engineered mini g alpha s subunit (41 kDa, Protein from Homo sapiens)
- Nb35 (17 kDa, Protein from Lama glama)
Resolution: 2.97 Å
EM Method: Single-particle
Fitted PDBs: 7wyb
Q-score: 0.352
Qian Y, Ma Z, Liu C, Li X, Zhu X, Wang N, Xu Z, Xia R, Liang J, Duan Y, Yin H, Xiong Y, Zhang A, Guo C, Chen Z, Huang Z, He Y
Mol Cell (2022) 82 pp. 4340-4352.e6 [ Pubmed: 36309016 DOI: doi:10.1016/j.molcel.2022.10.009 ]
- Gpcr/g-protein complex (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Scfv16 (26 kDa, Protein from Homo sapiens)
- Isoform 3 of adhesion g protein-coupled receptor l3 (172 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Gpcr/g-protein complex (Complex)
- Adgrl3 (Complex from Mus musculus)
Resolution: 2.85 Å
EM Method: Single-particle
Fitted PDBs: 7wxu
Q-score: 0.533
Zhu X, Qian Y, Li X, Xu Z, Xia R, Wang N, Liang J, Yin H, Zhang A, Guo C, Wang G, He Y
Nat Commun (2022) 13 pp. 5513-5513 [ DOI: doi:10.1038/s41467-022-33173-4 Pubmed: 36127364 ]
- Gpcr/g-protein complex (Complex from Homo sapiens)
- Gpcr/g-protein (Complex from Lama glama)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Adhesion g-protein coupled receptor f1 (101 kDa, Protein from Homo sapiens)
- Nb35 (17 kDa, Protein from Lama glama)
- Engineered mini galpha-q subunit (41 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Nb35 (Complex)
Resolution: 2.84 Å
EM Method: Single-particle
Fitted PDBs: 7wxw
Q-score: 0.503
Zhu X, Qian Y, Li X, Xu Z, Xia R, Wang N, Liang J, Yin H, Zhang A, Guo C, Wang G, He Y
Nat Commun (2022) 13 pp. 5513-5513 [ DOI: doi:10.1038/s41467-022-33173-4 Pubmed: 36127364 ]
- Gpcr/g-protein complex (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Gpcr/g-protein (Complex from Lama glama)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Adhesion g-protein coupled receptor f1 (101 kDa, Protein from Homo sapiens)
- Nb35 (17 kDa, Protein from Lama glama)
- Engineered mini galpha-s subunit (41 kDa, Protein from Homo sapiens)
- Nb35 (Complex)
Resolution: 2.83 Å
EM Method: Single-particle
Fitted PDBs: 7wy0
Q-score: 0.45
Zhu X, Qian Y, Li X, Xu Z, Xia R, Wang N, Liang J, Yin H, Zhang A, Guo C, Wang G, He Y
Nat Commun (2022) 13 pp. 5513-5513 [ DOI: doi:10.1038/s41467-022-33173-4 Pubmed: 36127364 ]
- Gpcr/g-protein complex (Complex from Homo sapiens)
- Scfv16 (26 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Adhesion g-protein coupled receptor f1 (101 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Engineered g alpha 13 subunit (41 kDa, Protein from Homo sapiens)
Resolution: 2.83 Å
EM Method: Single-particle
Fitted PDBs: 7wz7
Q-score: 0.399
Zhu X, Qian Y, Li X, Xu Z, Xia R, Wang N, Liang J, Yin H, Zhang A, Guo C, Wang G, He Y
Nat Commun (2022) 13 pp. 5513-5513 [ DOI: doi:10.1038/s41467-022-33173-4 Pubmed: 36127364 ]
- Gpcr/g-protein complex (Complex from Homo sapiens)
- Scfv16 (26 kDa, Protein from Homo sapiens)
- Engineered g alpha 12 subunit (39 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Adhesion g-protein coupled receptor f1 (101 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
Resolution: 3.09 Å
EM Method: Single-particle
Fitted PDBs: 7x2v
Q-score: 0.316
Zhu X, Qian Y, Li X, Xu Z, Xia R, Wang N, Liang J, Yin H, Zhang A, Guo C, Wang G, He Y
Nat Commun (2022) 13 pp. 5513-5513 [ DOI: doi:10.1038/s41467-022-33173-4 Pubmed: 36127364 ]
- Gpcr/g-protein complex (Complex from Homo sapiens)
- Scfv16 (26 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Adhesion g-protein coupled receptor f1 (101 kDa, Protein from Homo sapiens)