Cryo-EM structure of RNase-treated RESC-A in trypanosomal RNA editing
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8fn4
Q-score: 0.416
Liu S, Wang H, Li X, Zhang F, Lee JKJ, Li Z, Yu C, Hu JJ, Zhao X, Suematsu T, Alvarez-Cabrera AL, Liu Q, Zhang L, Huang L, Aphasizheva I, Aphasizhev R, Zhou ZH
Science (2023) 381 pp. eadg4725-eadg4725 [ Pubmed: 37410820 DOI: doi:10.1126/science.adg4725 ]
- Rna-editing substrate-binding complex protein 4 (resc4) (120 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 5 (resc5) (43 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 2 (resc2) (55 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 1 (resc1) (52 kDa, Protein from Trypanosoma brucei)
- Resc5-tagged isolate with rnase treatment (Complex from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 6 (resc6) (57 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 3 (resc3) (53 kDa, Protein from Trypanosoma brucei)
Cryo-EM structure of RNase-untreated RESC-A in trypanosomal RNA editing
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8fn6
Q-score: 0.386
Liu S, Wang H, Li X, Zhang F, Lee JKJ, Li Z, Yu C, Hu JJ, Zhao X, Suematsu T, Alvarez-Cabrera AL, Liu Q, Zhang L, Huang L, Aphasizheva I, Aphasizhev R, Zhou ZH
Science (2023) 381 pp. eadg4725-eadg4725 [ Pubmed: 37410820 DOI: doi:10.1126/science.adg4725 ]
- Rna-editing substrate-binding complex protein 4 (resc4) (120 kDa, Protein from Trypanosoma brucei)
- Grna (14 kDa, RNA from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 2 (resc2) (55 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 5 (resc5) (43 kDa, Protein from Trypanosoma brucei)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Rna-editing substrate-binding complex protein 1 (resc1) (52 kDa, Protein from Trypanosoma brucei)
- Resc5-tagged isolate without rnase treatment (Complex from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 6 (resc6) (57 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 3 (resc3) (53 kDa, Protein from Trypanosoma brucei)
Cryo-EM structure of RNase-treated RESC-C in trypanosomal RNA editing
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8fnc
Q-score: 0.533
Liu S, Wang H, Li X, Zhang F, Lee JKJ, Li Z, Yu C, Hu JJ, Zhao X, Suematsu T, Alvarez-Cabrera AL, Liu Q, Zhang L, Huang L, Aphasizheva I, Aphasizhev R, Zhou ZH
Science (2023) 381 pp. eadg4725-eadg4725 [ Pubmed: 37410820 DOI: doi:10.1126/science.adg4725 ]
- Rap domain-containing protein (60 kDa, Protein from Trypanosoma brucei)
- Mrna (5 kDa, RNA from Trypanosoma brucei)
- Mitochondrial rna binding complex 1 subunit (61 kDa, Protein from Trypanosoma brucei)
- Resc5-tagged isolate with rnase treatment (Complex from Trypanosoma brucei)
- Phytanoyl-coa dioxygenase family protein (41 kDa, Protein from Trypanosoma brucei)
- Rxlr effector protein (18 kDa, Protein from Trypanosoma brucei)
- Rap domain-containing protein (57 kDa, Protein from Trypanosoma brucei)
- Grna (4 kDa, RNA from Trypanosoma brucei)
- Mitochondrial rna binding protein (34 kDa, Protein from Trypanosoma brucei)
Cryo-EM structure of RNase-untreated RESC-C in trypanosomal RNA editing
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8fnf
Q-score: 0.448
Liu S, Wang H, Li X, Zhang F, Lee JKJ, Li Z, Yu C, Hu JJ, Zhao X, Suematsu T, Alvarez-Cabrera AL, Liu Q, Zhang L, Huang L, Aphasizheva I, Aphasizhev R, Zhou ZH
Science (2023) 381 pp. eadg4725-eadg4725 [ Pubmed: 37410820 DOI: doi:10.1126/science.adg4725 ]
- Mrna (6 kDa, RNA from Trypanosoma brucei)
- Rap domain-containing protein (60 kDa, Protein from Trypanosoma brucei)
- Mitochondrial rna binding complex 1 subunit (61 kDa, Protein from Trypanosoma brucei)
- Phytanoyl-coa dioxygenase family protein (41 kDa, Protein from Trypanosoma brucei)
- Rxlr effector protein (18 kDa, Protein from Trypanosoma brucei)
- Rap domain-containing protein (57 kDa, Protein from Trypanosoma brucei)
- Grna (4 kDa, RNA from Trypanosoma brucei)
- Resc5-tagged isolate without rnase treatment (Complex from Trypanosoma brucei)
- Mitochondrial rna binding protein (34 kDa, Protein from Trypanosoma brucei)
Cryo-EM structure of RNase-treated RESC-B in trypanosomal RNA editing
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8fni
Q-score: 0.443
Liu S, Wang H, Li X, Zhang F, Lee JKJ, Li Z, Yu C, Hu JJ, Zhao X, Suematsu T, Alvarez-Cabrera AL, Liu Q, Zhang L, Huang L, Aphasizheva I, Aphasizhev R, Zhou ZH
Science (2023) 381 pp. eadg4725-eadg4725 [ Pubmed: 37410820 DOI: doi:10.1126/science.adg4725 ]
- Rna-editing substrate-binding complex protein 11 (resc11) (103 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 5 (resc5) (43 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 9 (resc9) (96 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 8 (resc8) (61 kDa, Protein from Trypanosoma brucei)
- Resc5-tagged isolate with rnase treatment (Complex from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 10 (resc10) (60 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 13 (resc13) (32 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 14 (resc14) (41 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 7 (resc7) (18 kDa, Protein from Trypanosoma brucei)
- Grna (4 kDa, RNA from Trypanosoma brucei)
- Mrna (6 kDa, RNA from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 6 (resc6) (57 kDa, Protein from Trypanosoma brucei)
Cryo-EM structure of RNase-untreated RESC-B in trypanosomal RNA editing
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8fnk
Q-score: 0.37
Liu S, Wang H, Li X, Zhang F, Lee JKJ, Li Z, Yu C, Hu JJ, Zhao X, Suematsu T, Alvarez-Cabrera AL, Liu Q, Zhang L, Huang L, Aphasizheva I, Aphasizhev R, Zhou ZH
Science (2023) 381 pp. eadg4725-eadg4725 [ Pubmed: 37410820 DOI: doi:10.1126/science.adg4725 ]
- Rna-editing substrate-binding complex protein 11 (resc11) (103 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 5 (resc5) (43 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 9 (resc9) (96 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 8 (resc8) (61 kDa, Protein from Trypanosoma brucei)
- Mrna (15 kDa, RNA from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 10 (resc10) (60 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 13 (resc13) (32 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 14 (resc14) (41 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 7 (resc7) (18 kDa, Protein from Trypanosoma brucei)
- Resc5-tagged isolate without rnase treatment (Complex from Trypanosoma brucei)
- Grna (13 kDa, RNA from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 6 (resc6) (57 kDa, Protein from Trypanosoma brucei)
Cryo-EM structure of BAP1-ASXL1 bound to chromatosome
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8h1t
Q-score: 0.435
Ge W, Yu C, Li J, Yu Z, Li X, Zhang Y, Liu CP, Li Y, Tian C, Zhang X, Li G, Zhu B, Xu RM
Nature (2023) 616 pp. 176-182 [ DOI: doi:10.1038/s41586-023-05841-y Pubmed: 36991118 ]
- Histone h4 (11 kDa, Protein from Homo sapiens)
- Cryo-em structure of bap1-asxl1 bound to chromatosome (Complex from Homo sapiens)
- Dna (187-mer) (58 kDa, DNA from Homo sapiens)
- Histone h2a type 1-d (14 kDa, Protein from Homo sapiens)
- Ubiquitin (8 kDa, Protein from Homo sapiens)
- Histone h1.4 (23 kDa, Protein from Homo sapiens)
- Histone h3.1 (15 kDa, Protein from Homo sapiens)
- Histone h2b type 2-e (13 kDa, Protein from Homo sapiens)
- Dna (187-mer) (57 kDa, DNA from Homo sapiens)
- Polycomb group protein asxl1 (41 kDa, Protein from Homo sapiens)
- Ubiquitin carboxyl-terminal hydrolase bap1 (80 kDa, Protein from Homo sapiens)