Yeast U1 snRNP with humanized U1C Zinc-Finger domain
Resolution: 3.49 Å
EM Method: Single-particle
Fitted PDBs: 8w2o
Q-score: 0.417
Chalivendra S, Shi S, Li X, Kuang Z, Giovinazzo J, Zhang L, Rossi J, Wang J, Saviola AJ, Welty R, Liu S, Vaeth KF, Zhou ZH, Hansen KC, Taliaferro JM, Zhao R
RNA (2024) 30 pp. 1070-1088 [ DOI: doi:10.1261/rna.079917.123 Pubmed: 38688558 ]
- Small nuclear ribonucleoprotein sm d2 (12 kDa, Protein from Saccharomyces cerevisiae S288C)
- Protein nam8 (57 kDa, Protein from Saccharomyces cerevisiae S288C)
- U1snrnp (Complex from Saccharomyces cerevisiae S288C)
- Small nuclear ribonucleoprotein sm d1 (16 kDa, Protein from Saccharomyces cerevisiae S288C)
- Small nuclear ribonucleoprotein-associated protein b (22 kDa, Protein from Saccharomyces cerevisiae S288C)
- Act1 pre-mrna (59 kDa, RNA from Saccharomyces cerevisiae S288C)
- U1 snrna (182 kDa, RNA from Saccharomyces cerevisiae S288C)
- Small nuclear ribonucleoprotein g (8 kDa, Protein from Saccharomyces cerevisiae S288C)
- 56 kda u1 small nuclear ribonucleoprotein component (56 kDa, Protein from Saccharomyces cerevisiae S288C)
- Small nuclear ribonucleoprotein sm d3 (11 kDa, Protein from Saccharomyces cerevisiae S288C)
- Small nuclear ribonucleoprotein f (9 kDa, Protein from Saccharomyces cerevisiae S288C)
- U1 small nuclear ribonucleoprotein component prp42 (65 kDa, Protein from Saccharomyces cerevisiae S288C)
- Pre-mrna-processing factor 39 (74 kDa, Protein from Saccharomyces cerevisiae S288C)
- U1 small nuclear ribonucleoprotein a (40 kDa, Protein from Saccharomyces cerevisiae S288C)
- U1 small nuclear ribonucleoprotein 70 kda homolog (34 kDa, Protein from Saccharomyces cerevisiae S288C)
- U1 small nuclear ribonucleoprotein component snu71 (5 kDa, Protein from Saccharomyces cerevisiae S288C)
- Protein luc7 (30 kDa, Protein from Saccharomyces cerevisiae S288C)
- U1 small nuclear ribonucleoprotein c (27 kDa, Protein from Saccharomyces cerevisiae S288C)
- Small nuclear ribonucleoprotein e (10 kDa, Protein from Saccharomyces cerevisiae S288C)
Cryo-EM structure of RNase-treated RESC-A in trypanosomal RNA editing
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8fn4
Q-score: 0.416
Liu S, Wang H, Li X, Zhang F, Lee JKJ, Li Z, Yu C, Hu JJ, Zhao X, Suematsu T, Alvarez-Cabrera AL, Liu Q, Zhang L, Huang L, Aphasizheva I, Aphasizhev R, Zhou ZH
Science (2023) 381 pp. eadg4725-eadg4725 [ Pubmed: 37410820 DOI: doi:10.1126/science.adg4725 ]
- Rna-editing substrate-binding complex protein 4 (resc4) (120 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 5 (resc5) (43 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 2 (resc2) (55 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 1 (resc1) (52 kDa, Protein from Trypanosoma brucei)
- Resc5-tagged isolate with rnase treatment (Complex from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 6 (resc6) (57 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 3 (resc3) (53 kDa, Protein from Trypanosoma brucei)
Cryo-EM structure of RNase-untreated RESC-A in trypanosomal RNA editing
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8fn6
Q-score: 0.386
Liu S, Wang H, Li X, Zhang F, Lee JKJ, Li Z, Yu C, Hu JJ, Zhao X, Suematsu T, Alvarez-Cabrera AL, Liu Q, Zhang L, Huang L, Aphasizheva I, Aphasizhev R, Zhou ZH
Science (2023) 381 pp. eadg4725-eadg4725 [ Pubmed: 37410820 DOI: doi:10.1126/science.adg4725 ]
- Rna-editing substrate-binding complex protein 4 (resc4) (120 kDa, Protein from Trypanosoma brucei)
- Grna (14 kDa, RNA from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 2 (resc2) (55 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 5 (resc5) (43 kDa, Protein from Trypanosoma brucei)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Rna-editing substrate-binding complex protein 1 (resc1) (52 kDa, Protein from Trypanosoma brucei)
- Resc5-tagged isolate without rnase treatment (Complex from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 6 (resc6) (57 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 3 (resc3) (53 kDa, Protein from Trypanosoma brucei)
Cryo-EM structure of RNase-treated RESC-C in trypanosomal RNA editing
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8fnc
Q-score: 0.533
Liu S, Wang H, Li X, Zhang F, Lee JKJ, Li Z, Yu C, Hu JJ, Zhao X, Suematsu T, Alvarez-Cabrera AL, Liu Q, Zhang L, Huang L, Aphasizheva I, Aphasizhev R, Zhou ZH
Science (2023) 381 pp. eadg4725-eadg4725 [ Pubmed: 37410820 DOI: doi:10.1126/science.adg4725 ]
- Rap domain-containing protein (60 kDa, Protein from Trypanosoma brucei)
- Mrna (5 kDa, RNA from Trypanosoma brucei)
- Mitochondrial rna binding complex 1 subunit (61 kDa, Protein from Trypanosoma brucei)
- Resc5-tagged isolate with rnase treatment (Complex from Trypanosoma brucei)
- Phytanoyl-coa dioxygenase family protein (41 kDa, Protein from Trypanosoma brucei)
- Rxlr effector protein (18 kDa, Protein from Trypanosoma brucei)
- Rap domain-containing protein (57 kDa, Protein from Trypanosoma brucei)
- Grna (4 kDa, RNA from Trypanosoma brucei)
- Mitochondrial rna binding protein (34 kDa, Protein from Trypanosoma brucei)
Cryo-EM structure of RNase-untreated RESC-C in trypanosomal RNA editing
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8fnf
Q-score: 0.448
Liu S, Wang H, Li X, Zhang F, Lee JKJ, Li Z, Yu C, Hu JJ, Zhao X, Suematsu T, Alvarez-Cabrera AL, Liu Q, Zhang L, Huang L, Aphasizheva I, Aphasizhev R, Zhou ZH
Science (2023) 381 pp. eadg4725-eadg4725 [ Pubmed: 37410820 DOI: doi:10.1126/science.adg4725 ]
- Mrna (6 kDa, RNA from Trypanosoma brucei)
- Rap domain-containing protein (60 kDa, Protein from Trypanosoma brucei)
- Mitochondrial rna binding complex 1 subunit (61 kDa, Protein from Trypanosoma brucei)
- Phytanoyl-coa dioxygenase family protein (41 kDa, Protein from Trypanosoma brucei)
- Rxlr effector protein (18 kDa, Protein from Trypanosoma brucei)
- Rap domain-containing protein (57 kDa, Protein from Trypanosoma brucei)
- Grna (4 kDa, RNA from Trypanosoma brucei)
- Resc5-tagged isolate without rnase treatment (Complex from Trypanosoma brucei)
- Mitochondrial rna binding protein (34 kDa, Protein from Trypanosoma brucei)
Cryo-EM structure of RNase-treated RESC-B in trypanosomal RNA editing
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8fni
Q-score: 0.443
Liu S, Wang H, Li X, Zhang F, Lee JKJ, Li Z, Yu C, Hu JJ, Zhao X, Suematsu T, Alvarez-Cabrera AL, Liu Q, Zhang L, Huang L, Aphasizheva I, Aphasizhev R, Zhou ZH
Science (2023) 381 pp. eadg4725-eadg4725 [ Pubmed: 37410820 DOI: doi:10.1126/science.adg4725 ]
- Rna-editing substrate-binding complex protein 11 (resc11) (103 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 5 (resc5) (43 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 9 (resc9) (96 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 8 (resc8) (61 kDa, Protein from Trypanosoma brucei)
- Resc5-tagged isolate with rnase treatment (Complex from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 10 (resc10) (60 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 13 (resc13) (32 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 14 (resc14) (41 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 7 (resc7) (18 kDa, Protein from Trypanosoma brucei)
- Grna (4 kDa, RNA from Trypanosoma brucei)
- Mrna (6 kDa, RNA from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 6 (resc6) (57 kDa, Protein from Trypanosoma brucei)
Cryo-EM structure of RNase-untreated RESC-B in trypanosomal RNA editing
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8fnk
Q-score: 0.37
Liu S, Wang H, Li X, Zhang F, Lee JKJ, Li Z, Yu C, Hu JJ, Zhao X, Suematsu T, Alvarez-Cabrera AL, Liu Q, Zhang L, Huang L, Aphasizheva I, Aphasizhev R, Zhou ZH
Science (2023) 381 pp. eadg4725-eadg4725 [ Pubmed: 37410820 DOI: doi:10.1126/science.adg4725 ]
- Rna-editing substrate-binding complex protein 11 (resc11) (103 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 5 (resc5) (43 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 9 (resc9) (96 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 8 (resc8) (61 kDa, Protein from Trypanosoma brucei)
- Mrna (15 kDa, RNA from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 10 (resc10) (60 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 13 (resc13) (32 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 14 (resc14) (41 kDa, Protein from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 7 (resc7) (18 kDa, Protein from Trypanosoma brucei)
- Resc5-tagged isolate without rnase treatment (Complex from Trypanosoma brucei)
- Grna (13 kDa, RNA from Trypanosoma brucei)
- Rna-editing substrate-binding complex protein 6 (resc6) (57 kDa, Protein from Trypanosoma brucei)
Native RhopH complex of the malaria parasite Plasmodium falciparum
Resolution: 3.72 Å
EM Method: Single-particle
Fitted PDBs: 7mrw
Q-score: 0.432
Ho CM, Jih J, Lai M, Li X, Goldberg DE, Beck JR, Zhou ZH
PNAS (2021) 118 [ DOI: doi:10.1073/pnas.2100514118 Pubmed: 34446549 ]
- High molecular mass rhoptry protein complex (rhoph complex) (Complex from Plasmodium falciparum NF54)
- Cytoadherence linked asexual protein 3.1 (167 kDa, Protein from Plasmodium falciparum NF54)
- High molecular weight rhoptry protein 3 (104 kDa, Protein from Plasmodium falciparum NF54)
- High molecular weight rhoptry protein 2 (162 kDa, Protein from Plasmodium falciparum NF54)
CryoEM Plasmodium falciparum M18 aspartyl aminopeptidase
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6pev
Q-score: 0.532
Ho CM, Li X, Lai M, Terwilliger TC, Beck JR, Wohlschlegel J, Goldberg DE, Fitzpatrick AWP, Zhou ZH
Nat Methods (2020) 17 pp. 79-85 [ Pubmed: 31768063 DOI: doi:10.1038/s41592-019-0637-y ]
CryoEM Plasmodium falciparum glutamine synthetase
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6pew
Q-score: 0.509
Ho CM, Li X, Lai M, Terwilliger TC, Beck JR, Wohlschlegel J, Goldberg DE, Fitzpatrick AWP, Zhou ZH
Nat Methods (2020) 17 pp. 79-85 [ Pubmed: 31768063 DOI: doi:10.1038/s41592-019-0637-y ]