Curved structure of mPIEZO1-S2472E
Resolution: 4.07 Å
EM Method: Single-particle
Fitted PDBs: 8ixn
Q-score: 0.301
Liu S, Yang X, Chen X, Zhang X, Jiang J, Yuan J, Liu W, Wang L, Zhou H, Wu K, Tian B, Li X, Xiao B
Neuron (2024) [ Pubmed: 39719701 DOI: doi:10.1016/j.neuron.2024.11.020 ]
- Piezo-type mechanosensitive ion channel component 1 (292 kDa, Protein from Mus musculus)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- S2472e-curved structure (Complex from Mus musculus)
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)
Flattened structure of mPIEZO1-S2472E
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 8ixo
Q-score: 0.445
Liu S, Yang X, Chen X, Zhang X, Jiang J, Yuan J, Liu W, Wang L, Zhou H, Wu K, Tian B, Li X, Xiao B
Neuron (2024) [ Pubmed: 39719701 DOI: doi:10.1016/j.neuron.2024.11.020 ]
- Piezo-type mechanosensitive ion channel component 1 (292 kDa, Protein from Mus musculus)
- S2472e-intermediate structure (Complex from Mus musculus)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)
Resolution: 2.37 Å
EM Method: Single-particle
Fitted PDBs: 8yak
Q-score: 0.652
Hu Y, Dai L, Xu Y, Niu D, Yang X, Xie Z, Shen P, Li X, Li H, Zhang L, Min J, Guo RT, Chen CC
Int J Biol Macromol (2024) 278 pp. 134831-134831 [ Pubmed: 39163957 DOI: doi:10.1016/j.ijbiomac.2024.134831 ]
- Pwadh-g88d-d344n (Complex from Pseudoxanthomonas wuyuanensis)
- (2~{s})-2-[[(3~{r})-5-chloranyl-3-methyl-8-oxidanyl-1-oxidanylidene-3,4-dihydroisochromen-7-yl]carbonylamino]-3-phenyl-propanoic acid (403 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Imidazolonepropionase (43 kDa, Protein from Pseudoxanthomonas wuyuanensis)
Cryo-electron microscopic structure of an amide hydrolase from Pseudoxanthomonas wuyuanensis
Resolution: 2.33 Å
EM Method: Single-particle
Fitted PDBs: 8yag
Q-score: 0.665
Hu Y, Dai L, Xu Y, Niu D, Yang X, Xie Z, Shen P, Li X, Li H, Zhang L, Min J, Guo RT, Chen CC
Int J Biol Macromol (2024) 278 pp. 134831-134831 [ Pubmed: 39163957 DOI: doi:10.1016/j.ijbiomac.2024.134831 ]
- Imidazolonepropionase (43 kDa, Protein from Pseudoxanthomonas wuyuanensis)
- Pwadh (Complex from Pseudoxanthomonas wuyuanensis)
- Zinc ion (65 Da, Ligand)
A neutralizing nanobody VHH60 against wt SARS-CoV-2
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8xki
Q-score: 0.441
Liu Q, Lu Y, Cai C, Huang Y, Zhou L, Guan Y, Fu S, Lin Y, Yan H, Zhang Z, Li X, Yang X, Yang H, Guo H, Lan K, Chen Y, Hou SC, Xiong Y
Cell Death Dis (2024) 15 pp. 458-458 [ DOI: doi:10.1038/s41419-024-06802-7 Pubmed: 38937437 ]
- Nanobody (Complex from synthetic construct)
- Sars-cov-2 spike glycoprotein complex with vhh60 nanobody (Complex)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Nanobody vhh60 (13 kDa, Protein from synthetic construct)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
CryoEM structure of HpaCas9-sgRNA-dsDNA in the presence of AcrIIC4
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8hnv
Q-score: 0.464
Sun W, Cheng Z, Wang J, Yang J, Li X, Wang J, Chen M, Yang X, Sheng G, Lou J, Wang Y
PNAS (2023) 120 pp. e2303675120-e2303675120 [ Pubmed: 37494395 DOI: doi:10.1073/pnas.2303675120 ]
- Hpacas9/acriic4 (Complex)
- Crispr-associated endonuclease cas9 (121 kDa, Protein from Haemophilus parainfluenzae)
- Complex of hpacas9-sgrna-dna in the presence of acriic4 (194 kDa, Complex from Haemophilus parainfluenzae)
- Anti-crispr protein acriic4 (10 kDa, Protein from Haemophilus parainfluenzae)
- Target strand (10 kDa, DNA from Haemophilus parainfluenzae)
- Rna/dna (Complex)
- Sgrna (40 kDa, RNA from synthetic construct)
- Non-target strand (10 kDa, DNA from Haemophilus parainfluenzae)
Resolution: 3.23 Å
EM Method: Single-particle
Fitted PDBs: 7y1b
Q-score: 0.546
Zhang H, Yang X, Xue Y, Huang Y, Mo Y, Zhang H, Li N, Gao N, Li X, Wang S, Gao Y, Liao J
To Be Published
- Isoform 2 of basigin (29 kDa, Protein from Mus musculus)
- Light chain of 6e7f1 (25 kDa, Protein from Mus musculus)
- Heavy chain of 6e7f1 (25 kDa, Protein from Mus musculus)
- 3.2 angstrom cryo-em structure of extracellular region of mouse mct1/basigin-2 in complex with its monoclonal antibody 6e7f1 (100 kDa, Complex from Mus musculus)
Resolution: 5.03 Å
EM Method: Single-particle
Fitted PDBs: 7y1q
Q-score: 0.32
Zhang H, Yang X, Xue Y, Huang Y, Mo Y, Zhang H, Li N, Gao N, Li X, Wang S, Gao Y, Liao J
To Be Published
- Monocarboxylate transporter 1 (53 kDa, Protein from Mus musculus)
- Ternary complex of transmembrane regions of basigin with monocarboxylate transporter 1 (100 kDa, Complex from Mus musculus)
- Isoform 2 of basigin (29 kDa, Protein from Mus musculus)