Cryo-EM structure of LGR4 in complex with Rspo1 and RNF43
Resolution: 3.61 Å
EM Method: Single-particle
Fitted PDBs: 8wvu
Q-score: 0.363
To Be Published
- R-spondin-1 (13 kDa, Protein from Homo sapiens)
- Leucine-rich repeat-containing g-protein coupled receptor 4 (91 kDa, Protein from Homo sapiens)
- Lgr4 in complex with rspo1 and rnf43 (Complex from Homo sapiens)
- E3 ubiquitin-protein ligase rnf43 (18 kDa, Protein from Homo sapiens)
Cryo-EM structure of LGR4 in state I
Resolution: 3.35 Å
EM Method: Single-particle
Fitted PDBs: 8wvv
Q-score: 0.387
To Be Published
Cryo-EM structure of LGR4 in state II
Resolution: 3.53 Å
EM Method: Single-particle
Fitted PDBs: 8wvw
Q-score: 0.48
To Be Published
Cryo-EM structure of LGR4 in complex with Norrin
Resolution: 3.29 Å
EM Method: Single-particle
Fitted PDBs: 8wvy
Q-score: 0.467
To Be Published
- Leucine-rich repeat-containing g-protein coupled receptor 4 (91 kDa, Protein from Homo sapiens)
- Norrin (11 kDa, Protein from Homo sapiens)
- Lgr4 in complex with norrin (Complex from Homo sapiens)
Cryo-EM structure of LGR4 in complex with Norrin
To Be Published
CryoEM map of de novo designed oligomeric protein C4-71_6x
Edman NI, Phal A, Redler RL, Schlichthaerle T, Srivatsan SR, Ehnes DD, Etemadi A, An SJ, Favor A, Li Z, Praetorius F, Gordon M, Vincent T, Marchiano S, Blakely L, Lin C, Yang W, Coventry B, Hicks DR, Cao L, Bethel N, Heine P, Murray A, Gerben S, Carter L, Miranda M, Negahdari B, Lee S, Trapnell C, Zheng Y, Murry CE, Schweppe DK, Freedman BS, Stewart L, Ekiert DC, Schlessinger J, Shendure J, Bhabha G, Ruohola-Baker H, Baker D
Cell (2024) 187 pp. 3726-3740.e43 [ Pubmed: 38861993 DOI: doi:10.1016/j.cell.2024.05.025 ]
CryoEM map of de novo designed oligomeric protein C4-71_8x
Edman NI, Phal A, Redler RL, Schlichthaerle T, Srivatsan SR, Ehnes DD, Etemadi A, An SJ, Favor A, Li Z, Praetorius F, Gordon M, Vincent T, Marchiano S, Blakely L, Lin C, Yang W, Coventry B, Hicks DR, Cao L, Bethel N, Heine P, Murray A, Gerben S, Carter L, Miranda M, Negahdari B, Lee S, Trapnell C, Zheng Y, Murry CE, Schweppe DK, Freedman BS, Stewart L, Ekiert DC, Schlessinger J, Shendure J, Bhabha G, Ruohola-Baker H, Baker D
Cell (2024) 187 pp. 3726-3740.e43 [ Pubmed: 38861993 DOI: doi:10.1016/j.cell.2024.05.025 ]
CryoEM map of de novo designed oligomeric protein C6-71
Edman NI, Phal A, Redler RL, Schlichthaerle T, Srivatsan SR, Ehnes DD, Etemadi A, An SJ, Favor A, Li Z, Praetorius F, Gordon M, Vincent T, Marchiano S, Blakely L, Lin C, Yang W, Coventry B, Hicks DR, Cao L, Bethel N, Heine P, Murray A, Gerben S, Carter L, Miranda M, Negahdari B, Lee S, Trapnell C, Zheng Y, Murry CE, Schweppe DK, Freedman BS, Stewart L, Ekiert DC, Schlessinger J, Shendure J, Bhabha G, Ruohola-Baker H, Baker D
Cell (2024) 187 pp. 3726-3740.e43 [ Pubmed: 38861993 DOI: doi:10.1016/j.cell.2024.05.025 ]