Cryo-EM structure of LGR4 in complex with Rspo1 and RNF43
Resolution: 3.61 Å
EM Method: Single-particle
Fitted PDBs: 8wvu
Q-score: 0.363
To Be Published
- R-spondin-1 (13 kDa, Protein from Homo sapiens)
- Leucine-rich repeat-containing g-protein coupled receptor 4 (91 kDa, Protein from Homo sapiens)
- Lgr4 in complex with rspo1 and rnf43 (Complex from Homo sapiens)
- E3 ubiquitin-protein ligase rnf43 (18 kDa, Protein from Homo sapiens)
Cryo-EM structure of LGR4 in state I
Resolution: 3.35 Å
EM Method: Single-particle
Fitted PDBs: 8wvv
Q-score: 0.387
To Be Published
Cryo-EM structure of LGR4 in state II
Resolution: 3.53 Å
EM Method: Single-particle
Fitted PDBs: 8wvw
Q-score: 0.48
To Be Published
Cryo-EM structure of LGR4 in complex with Norrin
Resolution: 3.29 Å
EM Method: Single-particle
Fitted PDBs: 8wvy
Q-score: 0.467
To Be Published
- Norrin (11 kDa, Protein from Homo sapiens)
- Lgr4 in complex with norrin (Complex from Homo sapiens)
- Leucine-rich repeat-containing g-protein coupled receptor 4 (91 kDa, Protein from Homo sapiens)
Resolution: 3.28 Å
EM Method: Single-particle
Fitted PDBs: 8wzb
Q-score: 0.395
Meng X, Xu C, Li J, Qiu B, Luo J, Hong Q, Tong Y, Fang C, Feng Y, Ma R, Shi X, Lin C, Pan C, Zhu X, Yan X, Cong Y
Nat Commun (2024) 15 pp. 362-362 [ Pubmed: 38191553 DOI: doi:10.1038/s41467-023-44577-1 ]
- Radial spoke head protein 9 homolog (31 kDa, Protein from Mus musculus)
- Nucleoside diphosphate kinase homolog 5 (25 kDa, Protein from Mus musculus)
- Dpy30 domain containing 2 (18 kDa, Protein from Mus musculus)
- Radial spoke head protein 3 homolog b (45 kDa, Protein from Mus musculus)
- Radial spoke head 1 homolog (35 kDa, Protein from Mus musculus)
- Radial spoke head-neck monomer complex of mouse (Complex from Mus musculus)
- Dnaj homolog subfamily b member 13 (40 kDa, Protein from Mus musculus)
- Radial spoke head protein 4 homolog a (80 kDa, Protein from Mus musculus)
Resolution: 3.57 Å
EM Method: Single-particle
Fitted PDBs: 8x2u
Q-score: 0.353
Meng X, Xu C, Li J, Qiu B, Luo J, Hong Q, Tong Y, Fang C, Feng Y, Ma R, Shi X, Lin C, Pan C, Zhu X, Yan X, Cong Y
Nat Commun (2024) 15 pp. 362-362 [ Pubmed: 38191553 DOI: doi:10.1038/s41467-023-44577-1 ]
- Radial spoke head protein 9 homolog (31 kDa, Protein from Mus musculus)
- Nucleoside diphosphate kinase homolog 5 (25 kDa, Protein from Mus musculus)
- Dpy30 domain containing 2 (18 kDa, Protein from Mus musculus)
- Radial spoke head protein 3 homolog b (45 kDa, Protein from Mus musculus)
- Radial spoke head 1 homolog (35 kDa, Protein from Mus musculus)
- Dnaj homolog subfamily b member 13 (40 kDa, Protein from Mus musculus)
- Radial spoke head-neck dimer (Complex from Mus musculus)
- Radial spoke head protein 4 homolog a (80 kDa, Protein from Mus musculus)
CryoEM structure of designed modular protein oligomer C8-71
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8f6q
Q-score: 0.423
Edman NI, Phal A, Redler RL, Schlichthaerle T, Srivatsan SR, Ehnes DD, Etemadi A, An SJ, Favor A, Li Z, Praetorius F, Gordon M, Vincent T, Marchiano S, Blakely L, Lin C, Yang W, Coventry B, Hicks DR, Cao L, Bethel N, Heine P, Murray A, Gerben S, Carter L, Miranda M, Negahdari B, Lee S, Trapnell C, Zheng Y, Murry CE, Schweppe DK, Freedman BS, Stewart L, Ekiert DC, Schlessinger J, Shendure J, Bhabha G, Ruohola-Baker H, Baker D
Cell (2024) 187 pp. 3726-3740.e43 [ DOI: doi:10.1016/j.cell.2024.05.025 Pubmed: 38861993 ]
CryoEM structure of designed modular protein oligomer C6-79
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 8f6r
Q-score: 0.35
Edman NI, Phal A, Redler RL, Schlichthaerle T, Srivatsan SR, Ehnes DD, Etemadi A, An SJ, Favor A, Li Z, Praetorius F, Gordon M, Vincent T, Marchiano S, Blakely L, Lin C, Yang W, Coventry B, Hicks DR, Cao L, Bethel N, Heine P, Murray A, Gerben S, Carter L, Miranda M, Negahdari B, Lee S, Trapnell C, Zheng Y, Murry CE, Schweppe DK, Freedman BS, Stewart L, Ekiert DC, Schlessinger J, Shendure J, Bhabha G, Ruohola-Baker H, Baker D
Cell (2024) 187 pp. 3726-3740.e43 [ DOI: doi:10.1016/j.cell.2024.05.025 Pubmed: 38861993 ]
Cryo-EM Structure of R-loop monoclonal antibody S9.6 in recognizing RNA:DNA hybrids
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 7xlt
Q-score: 0.252
Li Q, Lin C, Luo Z, Li H, Li X, Sun Q
J Genet Genomics (2022) 49 pp. 677-680 [ DOI: doi:10.1016/j.jgg.2022.04.011 Pubmed: 35550870 ]
- Dna (12 kDa, DNA from Arabidopsis)
- Cryo-em structure of r-loop monoclonal antibody s9.6 in recognizing rna:dna hybrids (Complex from Mus musculus)
- S9.6 fab hc (23 kDa, Protein from Mus musculus)
- S9.6 fab lc (24 kDa, Protein from Mus musculus)
- Rna (13 kDa, RNA from Arabidopsis)
the Curved Structure of mPIEZO1 in Lipid Bilayer
Resolution: 3.46 Å
EM Method: Single-particle
Fitted PDBs: 7wlt
Q-score: 0.462
Yang X, Lin C, Chen X, Li S, Li X, Xiao B
Nature (2022) 604 pp. 377-383 [ DOI: doi:10.1038/s41586-022-04574-8 Pubmed: 35388220 ]
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)
- Piezo-type mechanosensitive ion channel component 1 (292 kDa, Protein from Mus musculus)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- The curved structure of mpiezo1 in lipid bilayer (Complex from Mus musculus)