Cryo-EM structure of LGR4 in complex with Rspo1 and RNF43
Resolution: 3.61 Å
EM Method: Single-particle
Fitted PDBs: 8wvu
Q-score: 0.363
To Be Published
- E3 ubiquitin-protein ligase rnf43 (18 kDa, Protein from Homo sapiens)
- Leucine-rich repeat-containing g-protein coupled receptor 4 (91 kDa, Protein from Homo sapiens)
- Lgr4 in complex with rspo1 and rnf43 (Complex from Homo sapiens)
- R-spondin-1 (13 kDa, Protein from Homo sapiens)
Cryo-EM structure of LGR4 in state I
Resolution: 3.35 Å
EM Method: Single-particle
Fitted PDBs: 8wvv
Q-score: 0.387
To Be Published
Cryo-EM structure of LGR4 in state II
Resolution: 3.53 Å
EM Method: Single-particle
Fitted PDBs: 8wvw
Q-score: 0.48
To Be Published
Cryo-EM structure of LGR4 in complex with Norrin
Resolution: 3.29 Å
EM Method: Single-particle
Fitted PDBs: 8wvy
Q-score: 0.467
To Be Published
- Norrin (11 kDa, Protein from Homo sapiens)
- Lgr4 in complex with norrin (Complex from Homo sapiens)
- Leucine-rich repeat-containing g-protein coupled receptor 4 (91 kDa, Protein from Homo sapiens)
Resolution: 3.28 Å
EM Method: Single-particle
Fitted PDBs: 8wzb
Q-score: 0.395
Meng X, Xu C, Li J, Qiu B, Luo J, Hong Q, Tong Y, Fang C, Feng Y, Ma R, Shi X, Lin C, Pan C, Zhu X, Yan X, Cong Y
Nat Commun (2024) 15 pp. 362-362 [ DOI: doi:10.1038/s41467-023-44577-1 Pubmed: 38191553 ]
- Radial spoke head protein 9 homolog (31 kDa, Protein from Mus musculus)
- Radial spoke head protein 3 homolog b (45 kDa, Protein from Mus musculus)
- Nucleoside diphosphate kinase homolog 5 (25 kDa, Protein from Mus musculus)
- Radial spoke head 1 homolog (35 kDa, Protein from Mus musculus)
- Dnaj homolog subfamily b member 13 (40 kDa, Protein from Mus musculus)
- Radial spoke head-neck monomer complex of mouse (Complex from Mus musculus)
- Radial spoke head protein 4 homolog a (80 kDa, Protein from Mus musculus)
- Dpy30 domain containing 2 (18 kDa, Protein from Mus musculus)
Resolution: 3.57 Å
EM Method: Single-particle
Fitted PDBs: 8x2u
Q-score: 0.353
Meng X, Xu C, Li J, Qiu B, Luo J, Hong Q, Tong Y, Fang C, Feng Y, Ma R, Shi X, Lin C, Pan C, Zhu X, Yan X, Cong Y
Nat Commun (2024) 15 pp. 362-362 [ DOI: doi:10.1038/s41467-023-44577-1 Pubmed: 38191553 ]
- Dnaj homolog subfamily b member 13 (40 kDa, Protein from Mus musculus)
- Nucleoside diphosphate kinase homolog 5 (25 kDa, Protein from Mus musculus)
- Radial spoke head-neck dimer (Complex from Mus musculus)
- Radial spoke head protein 3 homolog b (45 kDa, Protein from Mus musculus)
- Radial spoke head protein 4 homolog a (80 kDa, Protein from Mus musculus)
- Radial spoke head protein 9 homolog (31 kDa, Protein from Mus musculus)
- Dpy30 domain containing 2 (18 kDa, Protein from Mus musculus)
- Radial spoke head 1 homolog (35 kDa, Protein from Mus musculus)
The Cryo-EM structure of Drosophila Cryptochrome in complex with Timeless
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8dd7
Q-score: 0.386
Lin C, Feng S, DeOliveira CC, Crane BR
Nature (2023) 617 pp. 194-199 [ DOI: doi:10.1038/s41586-023-06009-4 Pubmed: 37100907 ]
- Complex of drosophila cryptochrome and timeless (264 kDa, Complex from Drosophila melanogaster)
- Protein timeless,methylated-dna--protein-cysteine methyltransferase fusion (179 kDa, Protein from Homo sapiens)
- Flavin-adenine dinucleotide (785 Da, Ligand)
- Methylated-dna--protein-cysteine methyltransferase,cryptochrome-1 fusion (83 kDa, Protein from Drosophila melanogaster)
Cryo-EM Structure of R-loop monoclonal antibody S9.6 in recognizing RNA:DNA hybrids
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 7xlt
Q-score: 0.252
Li Q, Lin C, Luo Z, Li H, Li X, Sun Q
J Genet Genomics (2022) 49 pp. 677-680 [ DOI: doi:10.1016/j.jgg.2022.04.011 Pubmed: 35550870 ]
- S9.6 fab lc (24 kDa, Protein from Mus musculus)
- Rna (13 kDa, RNA from Arabidopsis)
- Dna (12 kDa, DNA from Arabidopsis)
- S9.6 fab hc (23 kDa, Protein from Mus musculus)
- Cryo-em structure of r-loop monoclonal antibody s9.6 in recognizing rna:dna hybrids (Complex from Mus musculus)
the Curved Structure of mPIEZO1 in Lipid Bilayer
Resolution: 3.46 Å
EM Method: Single-particle
Fitted PDBs: 7wlt
Q-score: 0.462
Yang X, Lin C, Chen X, Li S, Li X, Xiao B
Nature (2022) 604 pp. 377-383 [ Pubmed: 35388220 DOI: doi:10.1038/s41586-022-04574-8 ]
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)
- The curved structure of mpiezo1 in lipid bilayer (Complex from Mus musculus)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Piezo-type mechanosensitive ion channel component 1 (292 kDa, Protein from Mus musculus)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
the Curved Structure of mPIEZO1 in Lipid Bilayer
Resolution: 6.81 Å
EM Method: Single-particle
Fitted PDBs: 7wlu
Q-score: 0.196
Yang X, Lin C, Chen X, Li S, Li X, Xiao B
Nature (2022) 604 pp. 377-383 [ Pubmed: 35388220 DOI: doi:10.1038/s41586-022-04574-8 ]
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- The flattened structure of mpiezo1 in lipid bilayer (Complex from Mus musculus)
- Piezo-type mechanosensitive ion channel component 1 (292 kDa, Protein from Mus musculus)