A neutralizing nanobody VHH60 against wt SARS-CoV-2
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8xki
Q-score: 0.441
Liu Q, Lu Y, Cai C, Huang Y, Zhou L, Guan Y, Fu S, Lin Y, Yan H, Zhang Z, Li X, Yang X, Yang H, Guo H, Lan K, Chen Y, Hou SC, Xiong Y
Cell Death Dis (2024) 15 pp. 458-458 [ DOI: doi:10.1038/s41419-024-06802-7 Pubmed: 38937437 ]
- Nanobody (Complex from synthetic construct)
- Sars-cov-2 spike glycoprotein complex with vhh60 nanobody (Complex)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Nanobody vhh60 (13 kDa, Protein from synthetic construct)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Cryo-EM structure of SARS-CoV-2 spike protein in complex with 8H12
Sun H, Deng T, Zhang Y, Lin Y, Jiang Y, Jiang Y, Huang Y, Song S, Cui L, Li T, Xiong H, Lan M, Liu L, Li Y, Fang Q, Yu K, Jiang W, Zhou L, Que Y, Zhang T, Yuan Q, Cheng T, Zhang Z, Yu H, Zhang J, Luo W, Li S, Zheng Q, Gu Y, Xia N
Protein Cell (2024) 15 pp. 121-134 [ Pubmed: 37470320 DOI: doi:10.1093/procel/pwad040 ]
Cryo-EM structure of SARS-CoV-2 spike protein in complex with 3E2
Sun H, Deng T, Zhang Y, Lin Y, Jiang Y, Jiang Y, Huang Y, Song S, Cui L, Li T, Xiong H, Lan M, Liu L, Li Y, Fang Q, Yu K, Jiang W, Zhou L, Que Y, Zhang T, Yuan Q, Cheng T, Zhang Z, Yu H, Zhang J, Luo W, Li S, Zheng Q, Gu Y, Xia N
Protein Cell (2024) 15 pp. 121-134 [ DOI: doi:10.1093/procel/pwad040 Pubmed: 37470320 ]
Cryo-EM structure of SARS-CoV-2 spike protein in complex with double nAbs 8H12 and 1C4
Sun H, Deng T, Zhang Y, Lin Y, Jiang Y, Jiang Y, Huang Y, Song S, Cui L, Li T, Xiong H, Lan M, Liu L, Li Y, Fang Q, Yu K, Jiang W, Zhou L, Que Y, Zhang T, Yuan Q, Cheng T, Zhang Z, Yu H, Zhang J, Luo W, Li S, Zheng Q, Gu Y, Xia N
Protein Cell (2024) 15 pp. 121-134 [ DOI: doi:10.1093/procel/pwad040 Pubmed: 37470320 ]
Cryo-EM structure of SARS-CoV-2 spike protein in complex with double nAbs 3E2 and 1C4
Sun H, Deng T, Zhang Y, Lin Y, Jiang Y, Jiang Y, Huang Y, Song S, Cui L, Li T, Xiong H, Lan M, Liu L, Li Y, Fang Q, Yu K, Jiang W, Zhou L, Que Y, Zhang T, Yuan Q, Cheng T, Zhang Z, Yu H, Zhang J, Luo W, Li S, Zheng Q, Gu Y, Xia N
Protein Cell (2024) 15 pp. 121-134 [ DOI: doi:10.1093/procel/pwad040 Pubmed: 37470320 ]
Resolution: 3.59 Å
EM Method: Single-particle
Fitted PDBs: 8iv4
Q-score: 0.506
Sun H, Deng T, Zhang Y, Lin Y, Jiang Y, Jiang Y, Huang Y, Song S, Cui L, Li T, Xiong H, Lan M, Liu L, Li Y, Fang Q, Yu K, Jiang W, Zhou L, Que Y, Zhang T, Yuan Q, Cheng T, Zhang Z, Yu H, Zhang J, Luo W, Li S, Zheng Q, Gu Y, Xia N
Protein Cell (2024) 15 pp. 121-134 [ DOI: doi:10.1093/procel/pwad040 Pubmed: 37470320 ]
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Cryo-em structure of sars-cov-2 spike protein in complex with double nabs 3e2 and 1c4 (Complex)
- Heavy chain of 3e2 (13 kDa, Protein from Mus musculus)
- Light chain of 3e2 (11 kDa, Protein from Mus musculus)
- Sars-cov-2 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Heavy chain of 8h12 (13 kDa, Protein from Mus musculus)
- Light chain of 8h12 (11 kDa, Protein from Mus musculus)
- Nabs 8h12 and 3e2 (Complex from Mus musculus)
Resolution: 3.77 Å
EM Method: Single-particle
Fitted PDBs: 8iv5
Q-score: 0.494
Sun H, Deng T, Zhang Y, Lin Y, Jiang Y, Jiang Y, Huang Y, Song S, Cui L, Li T, Xiong H, Lan M, Liu L, Li Y, Fang Q, Yu K, Jiang W, Zhou L, Que Y, Zhang T, Yuan Q, Cheng T, Zhang Z, Yu H, Zhang J, Luo W, Li S, Zheng Q, Gu Y, Xia N
Protein Cell (2024) 15 pp. 121-134 [ DOI: doi:10.1093/procel/pwad040 Pubmed: 37470320 ]
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Nabs 8h12,1c4 (Complex from Mus musculus)
- Heavy chain of 1c4 (13 kDa, Protein from Mus musculus)
- Light chain of 1c4 (11 kDa, Protein from Mus musculus)
- Sars-cov-2 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Cryo-em structure of sars-cov-2 spike protein in complex with 8h12 (Complex)
- Heavy chain of 8h12 (13 kDa, Protein from Mus musculus)
- Light chain of 8h12 (11 kDa, Protein from Mus musculus)
Cryo-EM structure of SARS-CoV-2 spike protein in complex with double nAbs 8H12 and 3E2
Sun H, Deng T, Zhang Y, Lin Y, Jiang Y, Jiang Y, Huang Y, Song S, Cui L, Li T, Xiong H, Lan M, Liu L, Li Y, Fang Q, Yu K, Jiang W, Zhou L, Que Y, Zhang T, Yuan Q, Cheng T, Zhang Z, Yu H, Zhang J, Luo W, Li S, Zheng Q, Gu Y, Xia N
Protein Cell (2024) 15 pp. 121-134 [ Pubmed: 37470320 DOI: doi:10.1093/procel/pwad040 ]
cryo-EM structure of SARS-CoV-2 Omicron BA.1 spike protein in complex with double nAbs 8H12 and 3E2
Sun H, Deng T, Zhang Y, Lin Y, Jiang Y, Jiang Y, Huang Y, Song S, Cui L, Li T, Xiong H, Lan M, Liu L, Li Y, Fang Q, Yu K, Jiang W, Zhou L, Que Y, Zhang T, Yuan Q, Cheng T, Zhang Z, Yu H, Zhang J, Luo W, Li S, Zheng Q, Gu Y, Xia N
Protein Cell (2024) 15 pp. 121-134 [ DOI: doi:10.1093/procel/pwad040 Pubmed: 37470320 ]
Resolution: 3.92 Å
EM Method: Single-particle
Fitted PDBs: 8iv8
Q-score: 0.444
Sun H, Deng T, Zhang Y, Lin Y, Jiang Y, Jiang Y, Huang Y, Song S, Cui L, Li T, Xiong H, Lan M, Liu L, Li Y, Fang Q, Yu K, Jiang W, Zhou L, Que Y, Zhang T, Yuan Q, Cheng T, Zhang Z, Yu H, Zhang J, Luo W, Li S, Zheng Q, Gu Y, Xia N
Protein Cell (2024) 15 pp. 121-134 [ DOI: doi:10.1093/procel/pwad040 Pubmed: 37470320 ]
- Nabs 3e2 and 1c4 (Complex from Mus musculus)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Cryo-em structure of sars-cov-2 spike protein in complex with double nabs 3e2 and 1c4 (Complex)
- Heavy chain of 3e2 (13 kDa, Protein from Mus musculus)
- Heavy chain of 1c4 (13 kDa, Protein from Mus musculus)
- Light chain of 1c4 (11 kDa, Protein from Mus musculus)
- Light chain of 3e2 (11 kDa, Protein from Mus musculus)
- Sars-cov-2 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)