Senktide bound to active human neurokinin 3 receptor in complex with Gq
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8jbf
Q-score: 0.524
Sun W, Yang F, Zhang H, Yuan Q, Ling S, Wang Y, Lv P, Li Z, Luo Y, Liu D, Yin W, Shi P, Xu HE, Tian C
Cell Discov (2023) 9 pp. 66-66 [ Pubmed: 37391393 DOI: doi:10.1038/s41421-023-00564-w ]
- Senktide bound to active human neurokinin 3 receptor in complex with gq heterotrimer (Complex from Homo sapiens)
- Guanine nucleotide-binding protein gq subunit alpha (41 kDa, Protein from Homo sapiens)
- Neuromedin-k receptor (44 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (41 kDa, Protein from Rattus norvegicus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Scfv16 nanobody (32 kDa, Protein from Mus musculoides)
- Senktide (915 Da, Protein from Homo sapiens)
Neurokinin B bound to active human neurokinin 3 receptor in complex with Gq
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8jbg
Q-score: 0.569
Sun W, Yang F, Zhang H, Yuan Q, Ling S, Wang Y, Lv P, Li Z, Luo Y, Liu D, Yin W, Shi P, Xu HE, Tian C
Cell Discov (2023) 9 pp. 66-66 [ Pubmed: 37391393 DOI: doi:10.1038/s41421-023-00564-w ]
- Neuromedin-k receptor (nk3r-pfastbac1) (158 kDa, Protein from Homo sapiens)
- Neurokinin b bound to active human neurokinin 3 receptor in complex with gq heterotrimer (Complex from Homo sapiens)
- Neurokinin-b (1 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (41 kDa, Protein from Rattus norvegicus)
- Guanine nucleotide-binding protein gq (g324) (41 kDa, Protein from Homo sapiens)
- Scfv16 nanobody (32 kDa, Protein from Mus musculus)
Substance P bound to active human neurokinin 3 receptor in complex with Gq
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8jbh
Q-score: 0.575
Sun W, Yang F, Zhang H, Yuan Q, Ling S, Wang Y, Lv P, Li Z, Luo Y, Liu D, Yin W, Shi P, Xu HE, Tian C
Cell Discov (2023) 9 pp. 66-66 [ Pubmed: 37391393 DOI: doi:10.1038/s41421-023-00564-w ]
- Substance p bound to active human neurokinin 3 receptor in complex with gq heterotrimer (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Scfv16 nanobody (32 kDa, Protein from Mus musculoides)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (41 kDa, Protein from Rattus norvegicus)
- Nk3r-pfastbac1 (158 kDa, Protein from Homo sapiens)
- Peptide from protachykinin-1 (1 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein gq subunit alpha (g324) (41 kDa, Protein from Homo sapiens)