Structure of the human Meckelin
Resolution: 3.34 Å
EM Method: Single-particle
Fitted PDBs: 7fh1
Q-score: 0.495
Sci Adv (2021) 7 pp. eabj9748-eabj9748 [ Pubmed: 34731008 DOI: doi:10.1126/sciadv.abj9748 ]
- Meckelin (114 kDa, Protein from Homo sapiens)
- Homodimer of meckelin (Complex from Homo sapiens)
Cryo_EM structure of delta N-NPC1L1-CLR
Resolution: 2.69 Å
EM Method: Single-particle
Fitted PDBs: 7dfw
Q-score: 0.584
Hu M, Yang F, Huang Y, You X, Liu D, Sun S, Sui SF
Sci Adv (2021) 7 [ Pubmed: 34272236 DOI: doi:10.1126/sciadv.abg3188 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Complex of delta n-npc1l1 with clr (Complex from Homo sapiens)
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)
- Npc1-like intracellular cholesterol transporter 1 (141 kDa, Protein from Homo sapiens)
- Dodecyl-beta-d-maltoside (510 Da, Ligand)
- Cholesterol (386 Da, Ligand)
Cryo_EM structure of delta N-NPC1L1-EZE
Resolution: 3.58 Å
EM Method: Single-particle
Fitted PDBs: 7dfz
Q-score: 0.481
Hu M, Yang F, Huang Y, You X, Liu D, Sun S, Sui SF
Sci Adv (2021) 7 [ Pubmed: 34272236 DOI: doi:10.1126/sciadv.abg3188 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- (3~{r},4~{s})-1-(4-fluorophenyl)-3-[(3~{s})-3-(4-fluorophenyl)-3-oxidanyl-propyl]-4-(4-hydroxyphenyl)azetidin-2-one (409 Da, Ligand)
- Delta n-hnpc1l1-eze (Complex from Homo sapiens)
- Npc1-like intracellular cholesterol transporter 1 (139 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 7df8
Q-score: 0.54
Hu M, Yang F, Huang Y, You X, Liu D, Sun S, Sui SF
Sci Adv (2021) 7 [ Pubmed: 34272236 DOI: doi:10.1126/sciadv.abg3188 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Full length npc1l1 (Cell from Homo sapiens)
- Dodecyl-beta-d-maltoside (510 Da, Ligand)
- Npc1-like intracellular cholesterol transporter 1 (139 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
The structure of CVA10 virus mature virion
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 6acu
Q-score: 0.086
Zhu R, Xu L, Zheng Q, Cui Y, Li S, He M, Yin Z, Liu D, Li S, Li Z, Chen Z, Yu H, Que Y, Liu C, Kong Z, Zhang J, Baker TS, Yan X, Zhou ZH, Cheng T, Xia N
Sci Adv (2018) 4 pp. eaat7459-eaat7459 [ DOI: doi:10.1126/sciadv.aat7459 Pubmed: 30255146 ]
- Vp2 (27 kDa, Protein from Coxsackievirus A10)
- Vp3 (26 kDa, Protein from Coxsackievirus A10)
- Vp4 (7 kDa, Protein from Coxsackievirus A10)
- Sphingosine (299 Da, Ligand)
- Coxsackievirus a10 (Virus from Coxsackievirus A10)
- Vp1 (33 kDa, Protein from Coxsackievirus A10)
The structure of CVA10 virus procapsid particle
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6acw
Q-score: 0.476
Zhu R, Xu L, Zheng Q, Cui Y, Li S, He M, Yin Z, Liu D, Li S, Li Z, Chen Z, Yu H, Que Y, Liu C, Kong Z, Zhang J, Baker TS, Yan X, Hong Zhou Z, Cheng T, Xia N
Sci Adv (2018) 4 pp. eaat7459-eaat7459 [ DOI: doi:10.1126/sciadv.aat7459 Pubmed: 30255146 ]
- Vp0 (35 kDa, Protein from Coxsackievirus A10)
- Coxsackievirus a10 (Virus from Coxsackievirus A10)
- Vp3 (26 kDa, Protein from Coxsackievirus A10)
- Vp1 (33 kDa, Protein from Coxsackievirus A10)
The structure of CVA10 virus A-particle
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 6acy
Q-score: 0.543
Zhu R, Xu L, Zheng Q, Cui Y, Li S, He M, Yin Z, Liu D, Li S, Li Z, Chen Z, Yu H, Que Y, Liu C, Kong Z, Zhang J, Baker TS, Yan X, Hong Zhou Z, Cheng T, Xia N
Sci Adv (2018) 4 pp. eaat7459-eaat7459 [ DOI: doi:10.1126/sciadv.aat7459 Pubmed: 30255146 ]
- Vp2 (27 kDa, Protein from Coxsackievirus A10)
- Coxsackievirus a10 (Virus from Coxsackievirus A10)
- Vp3 (26 kDa, Protein from Coxsackievirus A10)
- Vp1 (33 kDa, Protein from Coxsackievirus A10)
The structure of CVA10 virus A-particle from its complex with Fab 2G8
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 6acz
Q-score: 0.466
Zhu R, Xu L, Zheng Q, Cui Y, Li S, He M, Yin Z, Liu D, Li S, Li Z, Chen Z, Yu H, Que Y, Liu C, Kong Z, Zhang J, Baker TS, Yan X, Hong Zhou Z, Cheng T, Xia N
Sci Adv (2018) 4 pp. eaat7459-eaat7459 [ DOI: doi:10.1126/sciadv.aat7459 Pubmed: 30255146 ]
- Vp2 (27 kDa, Protein from Coxsackievirus A10)
- Coxsackievirus a10 (Virus from Coxsackievirus A10)
- Vp3 (26 kDa, Protein from Coxsackievirus A10)
- Vp1 (33 kDa, Protein from Coxsackievirus A10)
The structure of CVA10 mature virion in complex with Fab 2G8
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 6ad0
Q-score: 0.498
Zhu R, Xu L, Zheng Q, Cui Y, Li S, He M, Yin Z, Liu D, Li S, Li Z, Chen Z, Yu H, Que Y, Liu C, Kong Z, Zhang J, Baker TS, Yan X, Hong Zhou Z, Cheng T, Xia N
Sci Adv (2018) 4 pp. eaat7459-eaat7459 [ DOI: doi:10.1126/sciadv.aat7459 Pubmed: 30255146 ]
- Vp2 (27 kDa, Protein from Coxsackievirus A10)
- Vp3 (26 kDa, Protein from Coxsackievirus A10)
- Vp4 (7 kDa, Protein from Coxsackievirus A10)
- Sphingosine (299 Da, Ligand)
- Vl of fab 2g8 (12 kDa, Protein from Mus musculus)
- Vh of fab 2g8 (13 kDa, Protein from Mus musculus)
- Coxsackievirus a10 (Virus from Coxsackievirus A10)
- Vp1 (33 kDa, Protein from Coxsackievirus A10)
The structure of CVA10 procapsid from its complex with Fab 2G8
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6ad1
Q-score: 0.481
Zhu R, Xu L, Zheng Q, Cui Y, Li S, He M, Yin Z, Liu D, Li S, Li Z, Chen Z, Yu H, Que Y, Liu C, Kong Z, Zhang J, Baker TS, Yan X, Hong Zhou Z, Cheng T, Xia N
Sci Adv (2018) 4 pp. eaat7459-eaat7459 [ DOI: doi:10.1126/sciadv.aat7459 Pubmed: 30255146 ]
- Vp0 (35 kDa, Protein from Coxsackievirus A10)
- Coxsackievirus a10 (Virus from Coxsackievirus A10)
- Vp3 (26 kDa, Protein from Coxsackievirus A10)
- Vp1 (33 kDa, Protein from Coxsackievirus A10)