EB-bound E46K alpha-synuclein fibrils
Liu K, Tao Y, Zhao Q, Xia W, Li X, Zhang S, Yao Y, Xiang H, Han C, Tan L, Sun B, Li D, Li A, Liu C
PNAS (2024) 121 pp. e2321633121-e2321633121 [ DOI: doi:10.1073/pnas.2321633121 Pubmed: 39172784 ]
- Eb-bound e46k alpha-synuclein fibril (Complex from Homo sapiens)
- 4-azanyl-6-[[4-[4-[(~{e})-(8-azanyl-1-oxidanyl-5,7-disulfo-naphthalen-2-yl)diazenyl]-3-methyl-phenyl]-2-methyl-phenyl]diazenyl]-5-oxidanyl-naphthalene-1,3-disulfonic acid (872 Da, Ligand)
- Alpha-synuclein (14 kDa, Protein from Homo sapiens)
CR-bound E46K alpha-synuclein fibrils
Resolution: 3.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 8x7m
Q-score: 0.115
PiB-bound E46K mutanted alpha-synuclein fibrils
Resolution: 3.5 Å
EM Method: Helical reconstruction
Fitted PDBs: 8x7o
Q-score: 0.464
Liu K, Tao Y, Zhao Q, Xia W, Li X, Zhang S, Yao Y, Xiang H, Han C, Tan L, Sun B, Li D, Li A, Liu C
PNAS (2024) 121 pp. e2321633121-e2321633121 [ DOI: doi:10.1073/pnas.2321633121 Pubmed: 39172784 ]
- 2-[4-(methylamino)phenyl]-1,3-benzothiazol-6-ol (256 Da, Ligand)
- Pib-bound e46k mutated alpha-synuclein fibril (Complex from Homo sapiens)
- Alpha-synuclein (14 kDa, Protein from Homo sapiens)
BTA-2-bound E46K alpha-synuclein fibrils
Resolution: 3.4 Å
EM Method: Helical reconstruction
Fitted PDBs: 8zli
Q-score: 0.464
F0502B-bound E46K alpha-synuclein fibril
Resolution: 3.1 Å
EM Method: Helical reconstruction
Fitted PDBs: 8zlo
Q-score: 0.478
Cryo-EM structure of SARS-CoV-2 Omicron BA.2.12.1 RBD in complex with human ACE2 (local refinement)
Resolution: 3.09 Å
EM Method: Single-particle
Fitted PDBs: 7yhw
Q-score: 0.516
Zhao Z, Xie Y, Bai B, Luo C, Zhou J, Li W, Meng Y, Li L, Li D, Li X, Li X, Wang X, Sun J, Xu Z, Sun Y, Zhang W, Fan Z, Zhao X, Wu L, Ma J, Li OY, Shang G, Chai Y, Liu K, Wang P, Gao GF, Qi J
Nat Commun (2023) 14 pp. 4405-4405 [ Pubmed: 37479708 DOI: doi:10.1038/s41467-023-39942-z ]
- Zinc ion (65 Da, Ligand)
- Omicron ba.2.12.1 rbd (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Cryo-em structure of sars-cov-2 omicron ba.2.12.1 rbd in complex with human ace2 (local refinement) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Angiotensin-converting enzyme 2 (69 kDa, Protein from Homo sapiens)
- Ace2 (Complex)
Cryo-EM structure of SARS-CoV-2 Omicron BA.2 RBD in complex with human ACE2 (local refinement)
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 7yj3
Q-score: 0.468
Zhao Z, Xie Y, Bai B, Luo C, Zhou J, Li W, Meng Y, Li L, Li D, Li X, Li X, Wang X, Sun J, Xu Z, Sun Y, Zhang W, Fan Z, Zhao X, Wu L, Ma J, Li OY, Shang G, Chai Y, Liu K, Wang P, Gao GF, Qi J
Nat Commun (2023) 14 pp. 4405-4405 [ Pubmed: 37479708 DOI: doi:10.1038/s41467-023-39942-z ]
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Omicron ba.2 rbd (Complex)
- Cryo-em structure of sars-cov-2 omicron ba.2 rbd in complex with human ace2 (local refinement) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Angiotensin-converting enzyme 2 (69 kDa, Protein from Homo sapiens)
- Angiotensin-converting enzyme 2 (Complex from Homo sapiens)