SARS-CoV-2 Omicron BQ.1.1 RBD complexed with human ACE2
Resolution: 2.69 Å
EM Method: Single-particle
Fitted PDBs: 8wdy
Q-score: 0.511
Li W, Xu Z, Niu T, Xie Y, Zhao Z, Li D, He Q, Sun W, Shi K, Guo W, Chang Z, Liu K, Fan Z, Qi J, Gao GF
EMBO J (2024) 43 pp. 1484-1498 [ DOI: doi:10.1038/s44318-024-00062-z Pubmed: 38467833 ]
- Sars-cov-2 omicron bq.1.1 rbd complexed with human ace2 (Complex)
- Spike protein s1 (25 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Ace2 (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Bq.1.1 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
- Angiotensin-converting enzyme 2 (92 kDa, Protein from Homo sapiens)
SARS-CoV-2 Omicron BQ.1 RBD complexed with human ACE2
Resolution: 2.71 Å
EM Method: Single-particle
Fitted PDBs: 8wdz
Q-score: 0.508
Li W, Xu Z, Niu T, Xie Y, Zhao Z, Li D, He Q, Sun W, Shi K, Guo W, Chang Z, Liu K, Fan Z, Qi J, Gao GF
EMBO J (2024) 43 pp. 1484-1498 [ DOI: doi:10.1038/s44318-024-00062-z Pubmed: 38467833 ]
- Sars-cov-2 omicron bq.1 rbd complexed with human ace2 (Complex)
- Sars-cov-2 omicron bq.1 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike protein s1 (25 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Ace2 (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Angiotensin-converting enzyme 2 (92 kDa, Protein from Homo sapiens)
SARS-CoV-2 Omicron XBB RBD complexed with human ACE2
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8we0
Q-score: 0.472
Li W, Xu Z, Niu T, Xie Y, Zhao Z, Li D, He Q, Sun W, Shi K, Guo W, Chang Z, Liu K, Fan Z, Qi J, Gao GF
EMBO J (2024) 43 pp. 1484-1498 [ Pubmed: 38467833 DOI: doi:10.1038/s44318-024-00062-z ]
- Ace2 (Complex from Homo sapiens)
- Spike protein s2' (25 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
- Sars-cov-2 omicron xbb rbd complexed with human ace2 (Complex)
- Sars-cov-2 omicron xbb rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Angiotensin-converting enzyme 2 (92 kDa, Protein from Homo sapiens)
SARS-CoV-2 Omicron BF.7 RBD complexed with human ACE2
Resolution: 2.47 Å
EM Method: Single-particle
Fitted PDBs: 8we1
Q-score: 0.534
Li W, Xu Z, Niu T, Xie Y, Zhao Z, Li D, He Q, Sun W, Shi K, Guo W, Chang Z, Liu K, Fan Z, Qi J, Gao GF
EMBO J (2024) 43 pp. 1484-1498 [ DOI: doi:10.1038/s44318-024-00062-z Pubmed: 38467833 ]
- Sars-cov-2 omicron bf.7 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike protein s2' (25 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Ace2 (Complex from Homo sapiens)
- Sars-cov-2 omicron bf.7 rbd complexed with human ace2 (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Angiotensin-converting enzyme 2 (92 kDa, Protein from Homo sapiens)
SARS-CoV-2 Omicron XBB.1.5 RBD complexed with human ACE2 and S304
Resolution: 2.91 Å
EM Method: Single-particle
Fitted PDBs: 8we4
Q-score: 0.462
Li W, Xu Z, Niu T, Xie Y, Zhao Z, Li D, He Q, Sun W, Shi K, Guo W, Chang Z, Liu K, Fan Z, Qi J, Gao GF
EMBO J (2024) 43 pp. 1484-1498 [ DOI: doi:10.1038/s44318-024-00062-z Pubmed: 38467833 ]
- S304 fab light chain (23 kDa, Protein from Homo sapiens)
- Fabs304 (Complex from Homo sapiens)
- S304 fab heavy chain (24 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron xbb.1.5 rbd complexed with human ace2 and fab s304 (Complex)
- Zinc ion (65 Da, Ligand)
- Ace2 (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike protein s1 (25 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 omicron xbb.1.5 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Angiotensin-converting enzyme 2 (92 kDa, Protein from Homo sapiens)
SARS-CoV-2 RBD + IMCAS-123 + IMCAS-72 Fab
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 8xse
Q-score: 0.531
Tong Z, Tong J, Lei W, Xie Y, Cui Y, Jia G, Li S, Zhang Z, Cheng Z, Xing X, Ma H, Deng L, Zhang R, Zhao X, Liu K, Wang Q, Qi J, Huang H, Song R, Su Z, Wu G, Lou J, Gao GF
Cell Rep (2024) 43 pp. 114338-114338 [ DOI: doi:10.1016/j.celrep.2024.114338 Pubmed: 38850530 ]
- Imcas-72 l chain (23 kDa, Protein from Homo sapiens)
- Cryo-em structure of sars-cov-2 rbd + imcas-123 + imcas-72 fab (Complex)
- Sars-cov-2 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike protein s1 (23 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Imcas-72 h chain (24 kDa, Protein from Homo sapiens)
- Imcas-123 l chain (23 kDa, Protein from Homo sapiens)
- Imcas-123 h chain (23 kDa, Protein from Homo sapiens)
- Imcas-123 + imcas-72 fab (Complex from Homo sapiens)
SARS-CoV-2 RBD + IMCAS-364 + hACE2
Resolution: 2.16 Å
EM Method: Single-particle
Fitted PDBs: 8xsf
Q-score: 0.416
Tong Z, Tong J, Lei W, Xie Y, Cui Y, Jia G, Li S, Zhang Z, Cheng Z, Xing X, Ma H, Deng L, Zhang R, Zhao X, Liu K, Wang Q, Qi J, Huang H, Song R, Su Z, Wu G, Lou J, Gao GF
Cell Rep (2024) 43 pp. 114338-114338 [ DOI: doi:10.1016/j.celrep.2024.114338 Pubmed: 38850530 ]
- Imcas-364 h chain (50 kDa, Protein from Homo sapiens)
- Sars-cov-2 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Cryo-em structure of sars-cov-2 rbd + imcas-364 + hace2 (global refinement) (Complex)
- Imcas-364 l chain (23 kDa, Protein from Homo sapiens)
- Spike protein s1 (23 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Ace2 (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Imcas-364 (Complex from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Angiotensin-converting enzyme 2 (92 kDa, Protein from Homo sapiens)
SARS-CoV-2 RBD + IMCAS-364 (Local Refinement)
Resolution: 2.1 Å
EM Method: Single-particle
Fitted PDBs: 8xsi
Q-score: 0.555
Tong Z, Tong J, Lei W, Xie Y, Cui Y, Jia G, Li S, Zhang Z, Cheng Z, Xing X, Ma H, Deng L, Zhang R, Zhao X, Liu K, Wang Q, Qi J, Huang H, Song R, Su Z, Wu G, Lou J, Gao GF
Cell Rep (2024) 43 pp. 114338-114338 [ DOI: doi:10.1016/j.celrep.2024.114338 Pubmed: 38850530 ]
- Imcas-364 h chain (50 kDa, Protein from Homo sapiens)
- Sars-cov-2 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Cryo-em structure of sars-cov-2 rbd + imcas-364 (local refinement) (Complex)
- Imcas-364 l chain (23 kDa, Protein from Homo sapiens)
- Spike protein s1 (23 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Imcas-364 (Complex from Homo sapiens)
SARS-CoV-2 Omicron BA.4 RBD + IMCAS-316 + ACE2
Resolution: 2.61 Å
EM Method: Single-particle
Fitted PDBs: 8xsj
Q-score: 0.453
Tong Z, Tong J, Lei W, Xie Y, Cui Y, Jia G, Li S, Zhang Z, Cheng Z, Xing X, Ma H, Deng L, Zhang R, Zhao X, Liu K, Wang Q, Qi J, Huang H, Song R, Su Z, Wu G, Lou J, Gao GF
Cell Rep (2024) 43 pp. 114338-114338 [ DOI: doi:10.1016/j.celrep.2024.114338 Pubmed: 38850530 ]
- Spike protein s1 (25 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Imcas-316 h chain (24 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Cryo-em structure of sars-cov-2 omicron ba.4 rbd + imcas-316 + ace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Imcas-316 l chain (23 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Angiotensin-converting enzyme 2 (92 kDa, Protein from Homo sapiens)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8xsl
Q-score: 0.359
Tong Z, Tong J, Lei W, Xie Y, Cui Y, Jia G, Li S, Zhang Z, Cheng Z, Xing X, Ma H, Deng L, Zhang R, Zhao X, Liu K, Wang Q, Qi J, Huang H, Song R, Su Z, Wu G, Lou J, Gao GF
Cell Rep (2024) 43 pp. 114338-114338 [ DOI: doi:10.1016/j.celrep.2024.114338 Pubmed: 38850530 ]
- Imcas-123 light chain (23 kDa, Protein from Homo sapiens)
- Imcas-123 heavy chain (23 kDa, Protein from Homo sapiens)
- Cryo-em structure of sars-cov-2 spike + imcas-123 (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)