SARS-CoV-2 RBD + IMCAS-123 + IMCAS-72 Fab
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 8xse
Q-score: 0.531
Tong Z, Tong J, Lei W, Xie Y, Cui Y, Jia G, Li S, Zhang Z, Cheng Z, Xing X, Ma H, Deng L, Zhang R, Zhao X, Liu K, Wang Q, Qi J, Huang H, Song R, Su Z, Wu G, Lou J, Gao GF
Cell Rep (2024) 43 pp. 114338-114338 [ DOI: doi:10.1016/j.celrep.2024.114338 Pubmed: 38850530 ]
- Imcas-123 l chain (23 kDa, Protein from Homo sapiens)
- Cryo-em structure of sars-cov-2 rbd + imcas-123 + imcas-72 fab (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Imcas-123 + imcas-72 fab (Complex from Homo sapiens)
- Imcas-72 h chain (24 kDa, Protein from Homo sapiens)
- Spike protein s1 (23 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Imcas-123 h chain (23 kDa, Protein from Homo sapiens)
- Imcas-72 l chain (23 kDa, Protein from Homo sapiens)
SARS-CoV-2 RBD + IMCAS-364 + hACE2
Resolution: 2.16 Å
EM Method: Single-particle
Fitted PDBs: 8xsf
Q-score: 0.416
Tong Z, Tong J, Lei W, Xie Y, Cui Y, Jia G, Li S, Zhang Z, Cheng Z, Xing X, Ma H, Deng L, Zhang R, Zhao X, Liu K, Wang Q, Qi J, Huang H, Song R, Su Z, Wu G, Lou J, Gao GF
Cell Rep (2024) 43 pp. 114338-114338 [ DOI: doi:10.1016/j.celrep.2024.114338 Pubmed: 38850530 ]
- Imcas-364 (Complex from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Imcas-364 h chain (50 kDa, Protein from Homo sapiens)
- Sars-cov-2 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Imcas-364 l chain (23 kDa, Protein from Homo sapiens)
- Cryo-em structure of sars-cov-2 rbd + imcas-364 + hace2 (global refinement) (Complex)
- Angiotensin-converting enzyme 2 (92 kDa, Protein from Homo sapiens)
- Ace2 (Complex from Homo sapiens)
- Spike protein s1 (23 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 RBD + IMCAS-364 (Local Refinement)
Resolution: 2.1 Å
EM Method: Single-particle
Fitted PDBs: 8xsi
Q-score: 0.555
Tong Z, Tong J, Lei W, Xie Y, Cui Y, Jia G, Li S, Zhang Z, Cheng Z, Xing X, Ma H, Deng L, Zhang R, Zhao X, Liu K, Wang Q, Qi J, Huang H, Song R, Su Z, Wu G, Lou J, Gao GF
Cell Rep (2024) 43 pp. 114338-114338 [ DOI: doi:10.1016/j.celrep.2024.114338 Pubmed: 38850530 ]
- Imcas-364 (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Imcas-364 h chain (50 kDa, Protein from Homo sapiens)
- Sars-cov-2 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Imcas-364 l chain (23 kDa, Protein from Homo sapiens)
- Cryo-em structure of sars-cov-2 rbd + imcas-364 (local refinement) (Complex)
- Spike protein s1 (23 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 Omicron BA.4 RBD + IMCAS-316 + ACE2
Resolution: 2.61 Å
EM Method: Single-particle
Fitted PDBs: 8xsj
Q-score: 0.453
Tong Z, Tong J, Lei W, Xie Y, Cui Y, Jia G, Li S, Zhang Z, Cheng Z, Xing X, Ma H, Deng L, Zhang R, Zhao X, Liu K, Wang Q, Qi J, Huang H, Song R, Su Z, Wu G, Lou J, Gao GF
Cell Rep (2024) 43 pp. 114338-114338 [ DOI: doi:10.1016/j.celrep.2024.114338 Pubmed: 38850530 ]
- Zinc ion (65 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Cryo-em structure of sars-cov-2 omicron ba.4 rbd + imcas-316 + ace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Angiotensin-converting enzyme 2 (92 kDa, Protein from Homo sapiens)
- Imcas-316 l chain (23 kDa, Protein from Homo sapiens)
- Imcas-316 h chain (24 kDa, Protein from Homo sapiens)
- Spike protein s1 (25 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8xsl
Q-score: 0.359
Tong Z, Tong J, Lei W, Xie Y, Cui Y, Jia G, Li S, Zhang Z, Cheng Z, Xing X, Ma H, Deng L, Zhang R, Zhao X, Liu K, Wang Q, Qi J, Huang H, Song R, Su Z, Wu G, Lou J, Gao GF
Cell Rep (2024) 43 pp. 114338-114338 [ DOI: doi:10.1016/j.celrep.2024.114338 Pubmed: 38850530 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Cryo-em structure of sars-cov-2 spike + imcas-123 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Imcas-123 heavy chain (23 kDa, Protein from Homo sapiens)
- Imcas-123 light chain (23 kDa, Protein from Homo sapiens)
Cryo-EM structure of the 123-316 scDb/PT-RBD complex
Resolution: 2.86 Å
EM Method: Single-particle
Fitted PDBs: 8y0y
Q-score: 0.533
Tong Z, Tong J, Lei W, Xie Y, Cui Y, Jia G, Li S, Zhang Z, Cheng Z, Xing X, Ma H, Deng L, Zhang R, Zhao X, Liu K, Wang Q, Qi J, Huang H, Song R, Su Z, Wu G, Lou J, Gao GF
Cell Rep (2024) 43 pp. 114338-114338 [ DOI: doi:10.1016/j.celrep.2024.114338 Pubmed: 38850530 ]
- The 123-316 scdb/pt-rbd complex (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (23 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 123-316 scdb (56 kDa, Protein from Homo sapiens)
The structure of fox ACE2 and PT RBD complex
Resolution: 2.96 Å
EM Method: Single-particle
Fitted PDBs: 8xyz
Q-score: 0.454
Chen J, Sun J, Xu Z, Li L, Kang X, Luo C, Wang Q, Guo X, Li Y, Liu K, Wu Y
Virol Sin (2024) 39 pp. 609-618 [ Pubmed: 38866203 DOI: doi:10.1016/j.virs.2024.06.004 ]
- Zinc ion (65 Da, Ligand)
- Angiotensin-converting enzyme (71 kDa, Protein from Vulpes vulpes)
- Signal peptide, spike protein s1 (30 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- The structure of fox ace2 and pt rbd complex (Complex from Severe acute respiratory syndrome coronavirus 2)
The structure of fox ACE2 and SARS-CoV RBD complex
Resolution: 3.12 Å
EM Method: Single-particle
Fitted PDBs: 8xzb
Q-score: 0.421
Chen J, Sun J, Xu Z, Li L, Kang X, Luo C, Wang Q, Guo X, Li Y, Liu K, Wu Y
Virol Sin (2024) 39 pp. 609-618 [ Pubmed: 38866203 DOI: doi:10.1016/j.virs.2024.06.004 ]
- Spike protein s1 (25 kDa, Protein from Severe acute respiratory syndrome-related coronavirus)
- Zinc ion (65 Da, Ligand)
- Angiotensin-converting enzyme (71 kDa, Protein from Vulpes vulpes)
- The structure of fox ace2 and pt rbd complex (Complex from Severe acute respiratory syndrome coronavirus 2)
The structure of fox ACE2 and Omicron BF.7 RBD complex
Resolution: 3.47 Å
EM Method: Single-particle
Fitted PDBs: 8xzd
Q-score: 0.387
Chen J, Sun J, Xu Z, Li L, Kang X, Luo C, Wang Q, Guo X, Li Y, Liu K, Wu Y
Virol Sin (2024) 39 pp. 609-618 [ Pubmed: 38866203 DOI: doi:10.1016/j.virs.2024.06.004 ]
- Zinc ion (65 Da, Ligand)
- Angiotensin-converting enzyme (71 kDa, Protein from Vulpes vulpes)
- Spike protein s1 (27 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- The structure of fox ace2 and pt rbd complex (Complex from Severe acute respiratory syndrome coronavirus 2)
Cryo-EM structure of SARS-CoV-2 Delta RBD in complex with golden hamster ACE2 (local refinement)
Resolution: 2.96 Å
EM Method: Single-particle
Fitted PDBs: 8ka8
Q-score: 0.486
Niu S, Zhao Z, Liu Z, Rong X, Chai Y, Bai B, Han P, Shang G, Ren J, Wang Y, Zhao X, Liu K, Tian WX, Wang Q, Gao GF
J Virol (2024) 98 pp. e0115723-e0115723 [ Pubmed: 38305152 DOI: doi:10.1128/jvi.01157-23 ]
- Zinc ion (65 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike protein s1 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Delta rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Cryo-em structure of sars-cov-2 delta rbd in complex with golden hamster ace2 (local refinement) (Complex)
- Golden hamster angiotensin-converting enzyme 2 (Complex from Mesocricetus auratus)
- Angiotensin-converting enzyme (68 kDa, Protein from Mesocricetus auratus)