Extracellular domain of apo GC-A, state 1
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 9bcl
Q-score: 0.59
Liu S, Payne AM, Wang J, Zhu L, Paknejad N, Eng ET, Liu W, Miao Y, Hite RK, Huang XY
Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01426-z Pubmed: 39543315 ]
- Atrial natriuretic peptide receptor 1 (116 kDa, Protein from Homo sapiens)
- Chloride ion (35 Da, Ligand)
- Atrial natriuretic peptide receptor 1 dimer (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Extracellular domain of apo GC-A, state 2
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 9bcn
Q-score: 0.595
Liu S, Payne AM, Wang J, Zhu L, Paknejad N, Eng ET, Liu W, Miao Y, Hite RK, Huang XY
Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01426-z Pubmed: 39543315 ]
- Atrial natriuretic peptide receptor 1 (116 kDa, Protein from Homo sapiens)
- Chloride ion (35 Da, Ligand)
- Atrial natriuretic peptide receptor 1 dimer (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Intracellular domain of apo GC-A
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 9bco
Q-score: 0.344
Liu S, Payne AM, Wang J, Zhu L, Paknejad N, Eng ET, Liu W, Miao Y, Hite RK, Huang XY
Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01426-z Pubmed: 39543315 ]
- Atrial natriuretic peptide receptor 1 (116 kDa, Protein from Homo sapiens)
- Atrial natriuretic peptide receptor 1 dimer (Complex from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
Kinase homology domain of apo GC-A
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 9bcp
Q-score: 0.398
Liu S, Payne AM, Wang J, Zhu L, Paknejad N, Eng ET, Liu W, Miao Y, Hite RK, Huang XY
Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01426-z Pubmed: 39543315 ]
- Atrial natriuretic peptide receptor 1 (116 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Atrial natriuretic peptide receptor 1 dimer (Complex from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
Extracellular domain of GC-A bound to ANP
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 9bcq
Q-score: 0.599
Liu S, Payne AM, Wang J, Zhu L, Paknejad N, Eng ET, Liu W, Miao Y, Hite RK, Huang XY
Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01426-z Pubmed: 39543315 ]
- Chloride ion (35 Da, Ligand)
- Atrial natriuretic peptide receptor 1 dimer (Complex from Homo sapiens)
- Atrial natriuretic peptide receptor 1 (116 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Atrial natriuretic peptide (3 kDa, Protein from Homo sapiens)
Intracellular domain of GC-A bound to ANP
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 9bcs
Q-score: 0.359
Liu S, Payne AM, Wang J, Zhu L, Paknejad N, Eng ET, Liu W, Miao Y, Hite RK, Huang XY
Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01426-z Pubmed: 39543315 ]
- Atrial natriuretic peptide receptor 1 (116 kDa, Protein from Homo sapiens)
- Atrial natriuretic peptide receptor 1 dimer (Complex from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
Cyclase domain of GC-A bound to ANP
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9bcv
Q-score: 0.564
Liu S, Payne AM, Wang J, Zhu L, Paknejad N, Eng ET, Liu W, Miao Y, Hite RK, Huang XY
Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01426-z Pubmed: 39543315 ]
- Atrial natriuretic peptide receptor 1 dimer (Complex from Homo sapiens)
- Fab fragment (10 kDa, Protein from Mus musculus)
- Magnesium ion (24 Da, Ligand)
- Atrial natriuretic peptide receptor 1 (115 kDa, Protein from Homo sapiens)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 7jjo
Q-score: 0.599
Su M, Zhu L, Zhang Y, Paknejad N, Dey R, Huang J, Lee MY, Williams D, Jordan KD, Eng ET, Ernst OP, Meyerson JR, Hite RK, Walz T, Liu W, Huang XY
Mol Cell (2020) 80 pp. 59- [ DOI: doi:10.1016/j.molcel.2020.08.001 Pubmed: 32818430 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1, guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (Complex from Bos taurus)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (44 kDa, Protein from Bos taurus)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (Complex from Bos taurus)
- Nanobody 35 (Complex from Lama glama)
- Isoproterenol bound beta1 adrenergic receptor in complex with heterotrimeric gs protein (160 kDa, Complex)
- Beta1-adrenergic receptor (Complex from Meleagris gallopavo)
- Isoprenaline (211 Da, Ligand)
- Beta1-adrenergic receptor (57 kDa, Protein from Meleagris gallopavo)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Bos taurus)
- Nanobody 35 (15 kDa, Protein from Lama glama)