CryoEM structure of the APO-BAM complex in DDM detergent
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 9cnw
Q-score: 0.594
Sun D, Storek KM, Tegunov D, Yang Y, Arthur CP, Johnson M, Quinn JG, Liu W, Han G, Girgis HS, Alexander MK, Murchison AK, Shriver S, Tam C, Ijiri H, Inaba H, Sano T, Yanagida H, Nishikawa J, Heise CE, Fairbrother WJ, Tan MW, Skelton N, Sandoval W, Sellers BD, Ciferri C, Smith PA, Reid PC, Cunningham CN, Rutherford ST, Payandeh J
Nat Commun (2024) 15 pp. 8718-8718 [ DOI: doi:10.1038/s41467-024-52512-1 Pubmed: 39379361 ]
- Bamabcde complex (Complex from Escherichia coli)
- Outer membrane protein assembly factor bamc (36 kDa, Protein from Escherichia coli)
- Outer membrane protein assembly factor bama (90 kDa, Protein from Escherichia coli)
- Outer membrane protein assembly factor bamd (27 kDa, Protein from Escherichia coli)
- Outer membrane protein assembly factor bame (13 kDa, Protein from Escherichia coli)
- Outer membrane protein assembly factor bamb (41 kDa, Protein from Escherichia coli)
CryoEM structure of BAM in complex with the PTB1 closed-state inhibitor (in DDM detergent)
Resolution: 3.55 Å
EM Method: Single-particle
Fitted PDBs: 9cnx
Q-score: 0.461
Sun D, Storek KM, Tegunov D, Yang Y, Arthur CP, Johnson M, Quinn JG, Liu W, Han G, Girgis HS, Alexander MK, Murchison AK, Shriver S, Tam C, Ijiri H, Inaba H, Sano T, Yanagida H, Nishikawa J, Heise CE, Fairbrother WJ, Tan MW, Skelton N, Sandoval W, Sellers BD, Ciferri C, Smith PA, Reid PC, Cunningham CN, Rutherford ST, Payandeh J
Nat Commun (2024) 15 pp. 8718-8718 [ DOI: doi:10.1038/s41467-024-52512-1 Pubmed: 39379361 ]
- Bamabcde complex (Complex from Escherichia coli)
- Outer membrane protein assembly factor bamc (36 kDa, Protein from Escherichia coli)
- Outer membrane protein assembly factor bama (90 kDa, Protein from Escherichia coli)
- Circular peptide (1 kDa, Protein from synthetic construct)
- Zinc ion (65 Da, Ligand)
- Outer membrane protein assembly factor bamd (27 kDa, Protein from Escherichia coli)
- Outer membrane protein assembly factor bame (13 kDa, Protein from Escherichia coli)
- Outer membrane protein assembly factor bamb (41 kDa, Protein from Escherichia coli)
CryoEM structure of the APO-BAM complex in SMA nanodisc
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 9cny
Q-score: 0.39
Sun D, Storek KM, Tegunov D, Yang Y, Arthur CP, Johnson M, Quinn JG, Liu W, Han G, Girgis HS, Alexander MK, Murchison AK, Shriver S, Tam C, Ijiri H, Inaba H, Sano T, Yanagida H, Nishikawa J, Heise CE, Fairbrother WJ, Tan MW, Skelton N, Sandoval W, Sellers BD, Ciferri C, Smith PA, Reid PC, Cunningham CN, Rutherford ST, Payandeh J
Nat Commun (2024) 15 pp. 8718-8718 [ DOI: doi:10.1038/s41467-024-52512-1 Pubmed: 39379361 ]
- Bamabcde complex (Complex from Escherichia coli)
- Outer membrane protein assembly factor bamc (36 kDa, Protein from Escherichia coli)
- Outer membrane protein assembly factor bama (90 kDa, Protein from Escherichia coli)
- Outer membrane protein assembly factor bamd (27 kDa, Protein from Escherichia coli)
- Outer membrane protein assembly factor bame (13 kDa, Protein from Escherichia coli)
- Outer membrane protein assembly factor bamb (41 kDa, Protein from Escherichia coli)
Structure of BAM complexed with PTB2 ligand in detergent
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 9cnz
Q-score: 0.482
Sun D, Storek KM, Tegunov D, Yang Y, Arthur CP, Johnson M, Quinn JG, Liu W, Han G, Girgis HS, Alexander MK, Murchison AK, Shriver S, Tam C, Ijiri H, Inaba H, Sano T, Yanagida H, Nishikawa J, Heise CE, Fairbrother WJ, Tan MW, Skelton N, Sandoval W, Sellers BD, Ciferri C, Smith PA, Reid PC, Cunningham CN, Rutherford ST, Payandeh J
Nat Commun (2024) 15 pp. 8718-8718 [ DOI: doi:10.1038/s41467-024-52512-1 Pubmed: 39379361 ]
- Bamabcde complex (Complex from Escherichia coli)
- Outer membrane protein assembly factor bamc (36 kDa, Protein from Escherichia coli)
- Outer membrane protein assembly factor bama (90 kDa, Protein from Escherichia coli)
- Ptb2 circular peptide (2 kDa, Protein from synthetic construct)
- Outer membrane protein assembly factor bamd (27 kDa, Protein from Escherichia coli)
- Outer membrane protein assembly factor bame (13 kDa, Protein from Escherichia coli)
- Outer membrane protein assembly factor bamb (41 kDa, Protein from Escherichia coli)
CryoEM structure of BAM in complex with the PTB2 open-state inhibitor (in SMA nanodisc)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9co0
Q-score: 0.466
Sun D, Storek KM, Tegunov D, Yang Y, Arthur CP, Johnson M, Quinn JG, Liu W, Han G, Girgis HS, Alexander MK, Murchison AK, Shriver S, Tam C, Ijiri H, Inaba H, Sano T, Yanagida H, Nishikawa J, Heise CE, Fairbrother WJ, Tan MW, Skelton N, Sandoval W, Sellers BD, Ciferri C, Smith PA, Reid PC, Cunningham CN, Rutherford ST, Payandeh J
Nat Commun (2024) 15 pp. 8718-8718 [ DOI: doi:10.1038/s41467-024-52512-1 Pubmed: 39379361 ]
- Bamabcde complex (Complex from Escherichia coli)
- Outer membrane protein assembly factor bamc (36 kDa, Protein from Escherichia coli)
- Outer membrane protein assembly factor bama (90 kDa, Protein from Escherichia coli)
- Ptb2 circular peptide (2 kDa, Protein from synthetic construct)
- Outer membrane protein assembly factor bamd (27 kDa, Protein from Escherichia coli)
- Outer membrane protein assembly factor bame (13 kDa, Protein from Escherichia coli)
- Outer membrane protein assembly factor bamb (41 kDa, Protein from Escherichia coli)