Extracellular domain of GC-A bound to ANP
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 9bcq
Q-score: 0.599
Liu S, Payne AM, Wang J, Zhu L, Paknejad N, Eng ET, Liu W, Miao Y, Hite RK, Huang XY
Nat Struct Mol Biol (2024) [ Pubmed: 39543315 DOI: doi:10.1038/s41594-024-01426-z ]
- Atrial natriuretic peptide receptor 1 (116 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Atrial natriuretic peptide (3 kDa, Protein from Homo sapiens)
- Atrial natriuretic peptide receptor 1 dimer (Complex from Homo sapiens)
- Chloride ion (35 Da, Ligand)
Cyclase domain of GC-A bound to ANP
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9bcv
Q-score: 0.564
Liu S, Payne AM, Wang J, Zhu L, Paknejad N, Eng ET, Liu W, Miao Y, Hite RK, Huang XY
Nat Struct Mol Biol (2024) [ Pubmed: 39543315 DOI: doi:10.1038/s41594-024-01426-z ]
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
- Atrial natriuretic peptide receptor 1 dimer (Complex from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Fab fragment (10 kDa, Protein from Mus musculus)
- Atrial natriuretic peptide receptor 1 (115 kDa, Protein from Homo sapiens)
Lysophosphatidic acid receptor 1-Gi complex bound to LPA, state a
Resolution: 3.08 Å
EM Method: Single-particle
Fitted PDBs: 7td1
Q-score: 0.496
Liu S, Paknejad N, Zhu L, Kihara Y, Ray M, Chun J, Liu W, Hite RK, Huang XY
Nat Commun (2022) 13 pp. 731-731 [ Pubmed: 35136060 DOI: doi:10.1038/s41467-022-28417-2 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Bos taurus)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (43 kDa, Protein from Rattus norvegicus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Complex of lysophosphatidic acid receptor 1 with g-protein and lpa (Complex from Bos taurus)
- (2r)-2-hydroxy-3-(phosphonooxy)propyl (9e)-octadec-9-enoate (436 Da, Ligand)
- Lysophosphatidic acid receptor 1 (39 kDa, Protein from Homo sapiens)
Lysophosphatidic acid receptor 1-Gi complex bound to LPA, state a
Resolution: 3.11 Å
EM Method: Single-particle
Fitted PDBs: 7td2
Q-score: 0.506
Liu S, Paknejad N, Zhu L, Kihara Y, Ray M, Chun J, Liu W, Hite RK, Huang XY
Nat Commun (2022) 13 pp. 731-731 [ Pubmed: 35136060 DOI: doi:10.1038/s41467-022-28417-2 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Bos taurus)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (43 kDa, Protein from Rattus norvegicus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Complex of lysophosphatidic acid receptor 1 with g-protein and lpa (Complex from Bos taurus)
- (2r)-2-hydroxy-3-(phosphonooxy)propyl (9e)-octadec-9-enoate (436 Da, Ligand)
- Lysophosphatidic acid receptor 1 (39 kDa, Protein from Homo sapiens)
Sphingosine-1-phosphate receptor 1-Gi complex bound to S1P
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7td3
Q-score: 0.574
Liu S, Paknejad N, Zhu L, Kihara Y, Ray M, Chun J, Liu W, Hite RK, Huang XY
Nat Commun (2022) 13 pp. 731-731 [ Pubmed: 35136060 DOI: doi:10.1038/s41467-022-28417-2 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Bos taurus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (43 kDa, Protein from Rattus norvegicus)
- Complex of sphingosine-1-phosphate receptor 1 with g-protein and s1p (Complex from Bos taurus)
- (2s,3r,4e)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate (379 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Sphingosine 1-phosphate receptor 1 (43 kDa, Protein from Homo sapiens)