Cryo-EM structure of SPT-ORMDL3 (ORMDL3-deltaN2) complex
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7yj1
Q-score: 0.58
Xie T, Liu P, Wu X, Dong F, Zhang Z, Yue J, Mahawar U, Farooq F, Vohra H, Fang Q, Liu W, Wattenberg BW, Gong X
Nat Commun (2023) 14 pp. 3475-3475 [ DOI: doi:10.1038/s41467-023-39274-y Pubmed: 37308477 ]
- Pyridoxal-5'-phosphate (247 Da, Ligand)
- Serine palmitoyltransferase 1 (5 kDa, Protein from Homo sapiens)
- Orm1-like protein 3 (17 kDa, Protein from Homo sapiens)
- Spt-ormdl3 complex (Complex from Homo sapiens)
- Serine palmitoyltransferase 2 (63 kDa, Protein from Homo sapiens)
- Serine palmitoyltransferase small subunit a (10 kDa, Protein from Homo sapiens)
- Serine palmitoyltransferase 1 (46 kDa, Protein from Homo sapiens)
Cryo-EM structure of the dimeric atSPT-ORM1 complex
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7yjk
Q-score: 0.556
Liu P, Xie T, Wu X, Han G, Gupta SD, Zhang Z, Yue J, Dong F, Gable K, Niranjanakumari S, Li W, Wang L, Liu W, Yao R, Cahoon EB, Dunn TM, Gong X
Sci Adv (2023) 9 pp. eadg0728-eadg0728 [ DOI: doi:10.1126/sciadv.adg0728 Pubmed: 36989369 ]
- Ormdl family protein (18 kDa, Protein from Arabidopsis thaliana)
- Pyridoxal-5'-phosphate (247 Da, Ligand)
- Long chain base biosynthesis protein 2a (54 kDa, Protein from Arabidopsis thaliana)
- N-[(2s,3r,4e)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide (650 Da, Ligand)
- Spt-orm1 complex (Complex from Arabidopsis thaliana)
- Long chain base biosynthesis protein 1 (53 kDa, Protein from Arabidopsis thaliana)
- Transmembrane protein, putative (duf3317) (9 kDa, Protein from Arabidopsis thaliana)
Cryo-EM structure of the monomeric atSPT-ORM1 complex
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7yjm
Q-score: 0.585
Liu P, Xie T, Wu X, Han G, Gupta SD, Zhang Z, Yue J, Dong F, Gable K, Niranjanakumari S, Li W, Wang L, Liu W, Yao R, Cahoon EB, Dunn TM, Gong X
Sci Adv (2023) 9 pp. eadg0728-eadg0728 [ DOI: doi:10.1126/sciadv.adg0728 Pubmed: 36989369 ]
- Ormdl family protein (18 kDa, Protein from Arabidopsis thaliana)
- Pyridoxal-5'-phosphate (247 Da, Ligand)
- Long chain base biosynthesis protein 2a (54 kDa, Protein from Arabidopsis thaliana)
- Atlcb1 (6 kDa, Protein from Arabidopsis thaliana)
- N-[(2s,3r,4e)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide (650 Da, Ligand)
- Spt-orm1 complex (Complex from Arabidopsis thaliana)
- Transmembrane protein, putative (duf3317) (9 kDa, Protein from Arabidopsis thaliana)
- Atlcb1 (46 kDa, Protein from Arabidopsis thaliana)
Cryo-EM structure of the monomeric atSPT-ORM1 (ORM1-N17A) complex
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7yjn
Q-score: 0.526
Liu P, Xie T, Wu X, Han G, Gupta SD, Zhang Z, Yue J, Dong F, Gable K, Niranjanakumari S, Li W, Wang L, Liu W, Yao R, Cahoon EB, Dunn TM, Gong X
Sci Adv (2023) 9 pp. eadg0728-eadg0728 [ DOI: doi:10.1126/sciadv.adg0728 Pubmed: 36989369 ]
- Long chain base biosynthesis protein 1 (6 kDa, Protein from Arabidopsis thaliana)
- Long chain base biosynthesis protein 1 (46 kDa, Protein from Arabidopsis thaliana)
- Pyridoxal-5'-phosphate (247 Da, Ligand)
- Long chain base biosynthesis protein 2a (54 kDa, Protein from Arabidopsis thaliana)
- Ormdl family protein (18 kDa, Protein from Arabidopsis thaliana)
- Spt-orm1 complex (Complex from Arabidopsis thaliana)
- Transmembrane protein, putative (duf3317) (9 kDa, Protein from Arabidopsis thaliana)