Cryo-EM structure of the yeast SPT-ORM2 (ORM2-S3A) complex
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8iaj
Q-score: 0.567
Xie T, Dong F, Han G, Wu X, Liu P, Zhang Z, Zhong J, Niranjanakumari S, Gable K, Gupta SD, Liu W, Harrison PJ, Campopiano DJ, Dunn TM, Gong X
Cell Rep (2024) 43 pp. 113717-113717 [ Pubmed: 38285738 DOI: doi:10.1016/j.celrep.2024.113717 ]
- Serine palmitoyltransferase-regulating protein tsc3 (9 kDa, Protein from Saccharomyces cerevisiae)
- Pyridoxal-5'-phosphate (247 Da, Ligand)
- Protein orm2 (24 kDa, Protein from Saccharomyces cerevisiae S288C)
- N-[(2s,3r,4e)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide (650 Da, Ligand)
- Spt-orm2 complex (Complex from Saccharomyces cerevisiae)
- Serine palmitoyltransferase 2 (63 kDa, Protein from Saccharomyces cerevisiae)
- Chimera of long chain base biosynthesis protein 1 and serine palmitoyltransferase 1 (59 kDa, Protein from Saccharomyces cerevisiae S288C )
Cryo-EM structure of the yeast SPT-ORM2 (ORM2-S3A-N71A) complex
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8iak
Q-score: 0.548
Xie T, Dong F, Han G, Wu X, Liu P, Zhang Z, Zhong J, Niranjanakumari S, Gable K, Gupta SD, Liu W, Harrison PJ, Campopiano DJ, Dunn TM, Gong X
Cell Rep (2024) 43 pp. 113717-113717 [ Pubmed: 38285738 DOI: doi:10.1016/j.celrep.2024.113717 ]
- Protein orm2 (24 kDa, Protein from Saccharomyces cerevisiae)
- Serine palmitoyltransferase-regulating protein tsc3 (9 kDa, Protein from Saccharomyces cerevisiae)
- Pyridoxal-5'-phosphate (247 Da, Ligand)
- Chimera of long chain base biosynthesis protein 1 and serine palmitoyltransferase 1 (59 kDa, Protein from Saccharomyces cerevisiae S288C)
- Spt-orm2 complex (Complex from Saccharomyces cerevisiae)
- Serine palmitoyltransferase 2 (63 kDa, Protein from Saccharomyces cerevisiae)
Cryo-EM structure of the yeast SPT-ORM2 (ORM2-S3D) complex
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8iam
Q-score: 0.556
Xie T, Dong F, Han G, Wu X, Liu P, Zhang Z, Zhong J, Niranjanakumari S, Gable K, Gupta SD, Liu W, Harrison PJ, Campopiano DJ, Dunn TM, Gong X
Cell Rep (2024) 43 pp. 113717-113717 [ Pubmed: 38285738 DOI: doi:10.1016/j.celrep.2024.113717 ]
- Chimera of long chain base biosynthesis protein 1 and serine palmitoyltransferase 1 (59 kDa, Protein from Saccharomyces cerevisiae)
- Serine palmitoyltransferase-regulating protein tsc3 (9 kDa, Protein from Saccharomyces cerevisiae)
- Pyridoxal-5'-phosphate (247 Da, Ligand)
- N-[(2s,3r,4e)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide (650 Da, Ligand)
- Serine palmitoyltransferase 2 (63 kDa, Protein from Saccharomyces cerevisiae)
- Spt-orm2 complex (Complex from Saccharomyces cerevisiae)
- Protein orm2 (24 kDa, Protein from Saccharomyces cerevisiae)
Resolution: 3.1 Å
EM Method: Helical reconstruction
Fitted PDBs: 8azu
Q-score: 0.549
Stern AM, Yang Y, Jin S, Yamashita K, Meunier AL, Liu W, Cai Y, Ericsson M, Liu L, Goedert M, Scheres SHW, Selkoe DJ
Neuron (2023) 111 pp. 2012- [ Pubmed: 37167969 DOI: doi:10.1016/j.neuron.2023.04.007 ]
Resolution: 2.9 Å
EM Method: Helical reconstruction
Fitted PDBs: 8azs
Q-score: 0.648
Stern AM, Yang Y, Jin S, Yamashita K, Meunier AL, Liu W, Cai Y, Ericsson M, Liu L, Goedert M, Scheres SHW, Selkoe DJ
Neuron (2023) 111 pp. 2012- [ Pubmed: 37167969 DOI: doi:10.1016/j.neuron.2023.04.007 ]
Resolution: 3.7 Å
EM Method: Helical reconstruction
Fitted PDBs: 8azt
Q-score: 0.502
Stern AM, Yang Y, Jin S, Yamashita K, Meunier AL, Liu W, Cai Y, Ericsson M, Liu L, Goedert M, Scheres SHW, Selkoe DJ
Neuron (2023) 111 pp. 2012- [ Pubmed: 37167969 DOI: doi:10.1016/j.neuron.2023.04.007 ]