Cryo-EM structure of opioid receptor with biased agonist
Resolution: 3.45 Å
EM Method: Single-particle
Fitted PDBs: 8y45
Q-score: 0.407
Cheng L, Miao Z, Liu S, Li Z, Fu H, Xu C, Hu S, Zhao C, Liu Y, Zhao T, Liu W, Wang H, Liu R, Yan W, Tang X, Liu J, Shao Z, Ke B
Nat Commun (2024) 15 pp. 8284-8284 [ Pubmed: 39333070 DOI: doi:10.1038/s41467-024-52601-1 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-2 (40 kDa, Protein from Homo sapiens)
- Scfv16 (28 kDa, Protein from Mus musculus)
- Delta-type opioid receptor (36 kDa, Protein from Homo sapiens)
- ~{n},~{n}-diethyl-4-(5-oxidanylspiro[chromene-2,4'-piperidine]-4-yl)benzamide (392 Da, Ligand)
- Cryo-em structure of opioid receptor with biased agonist (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
Cryo-EM structure of GPR119-Gs-Nb35 complex with small molecule agonist MBX-2982
Resolution: 3.51 Å
EM Method: Single-particle
Fitted PDBs: 8vhf
Q-score: 0.449
Kim D-G, Liu W, Viner R, Cherezov V
To Be Published
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (45 kDa, Protein from Homo sapiens)
- Soluble cytochrome b562,glucose-dependent insulinotropic receptor,lgbit (67 kDa, Protein from Oplophorus gracilirostris)
- Nanobody35 (15 kDa, Complex from Lama glama)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1, hibit (40 kDa, Protein from Homo sapiens)
- The complex of gpr119-gs-nb35 (composite map) (177 kDa, Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- 2-[1-(5-ethylpyrimidin-2-yl)piperidin-4-yl]-4-[[4-(1,2,3,4-tetrazol-1-yl)phenoxy]methyl]-1,3-thiazole (448 Da, Ligand)
- G-protein complex (93 kDa, Complex from Homo sapiens)
- Nanobody35 (15 kDa, Protein from Lama glama)
- Glucose-dependent insulinotropic receptor (67 kDa, Complex from Escherichia coli)
S. enterica WbaP in a styrene maleic acid liponanoparticle
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 8t53
Q-score: 0.143
Dodge GJ, Anderson AJ, He Y, Liu W, Viner R, Imperiali B
eLife (2024) 12 [ Pubmed: 38358918 DOI: doi:10.7554/eLife.91125 ]
Structure of the asymmetric unit of SFTSV virion
Resolution: 5.2 Å
EM Method: Single-particle
Fitted PDBs: 8i4t
Q-score: 0.206
Du S, Peng R, Xu W, Qu X, Wang Y, Wang J, Li L, Tian M, Guan Y, Wang J, Wang G, Li H, Deng L, Shi X, Ma Y, Liu F, Sun M, Wei Z, Jin N, Liu W, Qi J, Liu Q, Liao M, Li C
Nat Commun (2023) 14 pp. 6333-6333 [ DOI: doi:10.1038/s41467-023-41804-7 Pubmed: 37816705 ]
- Dabie bandavirus (Virus from Dabie bandavirus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Envelopment polyprotein (54 kDa, Protein from Severe fever with thrombocytopenia syndrome virus)
- Envelopment polyprotein (61 kDa, Protein from Severe fever with thrombocytopenia syndrome virus)
Structure of SFTSV Gn-Gc heterodimer
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 8ilq
Q-score: 0.419
Du S, Peng R, Xu W, Qu X, Wang Y, Wang J, Li L, Tian M, Guan Y, Wang J, Wang G, Li H, Deng L, Shi X, Ma Y, Liu F, Sun M, Wei Z, Jin N, Liu W, Qi J, Liu Q, Liao M, Li C
Nat Commun (2023) 14 pp. 6333-6333 [ DOI: doi:10.1038/s41467-023-41804-7 Pubmed: 37816705 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Envelopment polyprotein (61 kDa, Protein from Severe fever with thrombocytopenia syndrome virus)
- Envelopment polyprotein (54 kDa, Protein from Severe fever with thrombocytopenia syndrome virus)
- Dabie bandavirus (Virus from Dabie bandavirus)
Cryo-EM structure of the dimeric atSPT-ORM1 complex
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7yjk
Q-score: 0.556
Liu P, Xie T, Wu X, Han G, Gupta SD, Zhang Z, Yue J, Dong F, Gable K, Niranjanakumari S, Li W, Wang L, Liu W, Yao R, Cahoon EB, Dunn TM, Gong X
Sci Adv (2023) 9 pp. eadg0728-eadg0728 [ DOI: doi:10.1126/sciadv.adg0728 Pubmed: 36989369 ]
- Ormdl family protein (18 kDa, Protein from Arabidopsis thaliana)
- Pyridoxal-5'-phosphate (247 Da, Ligand)
- Long chain base biosynthesis protein 2a (54 kDa, Protein from Arabidopsis thaliana)
- N-[(2s,3r,4e)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide (650 Da, Ligand)
- Spt-orm1 complex (Complex from Arabidopsis thaliana)
- Long chain base biosynthesis protein 1 (53 kDa, Protein from Arabidopsis thaliana)
- Transmembrane protein, putative (duf3317) (9 kDa, Protein from Arabidopsis thaliana)
Cryo-EM structure of the monomeric atSPT-ORM1 complex
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7yjm
Q-score: 0.585
Liu P, Xie T, Wu X, Han G, Gupta SD, Zhang Z, Yue J, Dong F, Gable K, Niranjanakumari S, Li W, Wang L, Liu W, Yao R, Cahoon EB, Dunn TM, Gong X
Sci Adv (2023) 9 pp. eadg0728-eadg0728 [ DOI: doi:10.1126/sciadv.adg0728 Pubmed: 36989369 ]
- Ormdl family protein (18 kDa, Protein from Arabidopsis thaliana)
- Pyridoxal-5'-phosphate (247 Da, Ligand)
- Long chain base biosynthesis protein 2a (54 kDa, Protein from Arabidopsis thaliana)
- Atlcb1 (6 kDa, Protein from Arabidopsis thaliana)
- N-[(2s,3r,4e)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide (650 Da, Ligand)
- Spt-orm1 complex (Complex from Arabidopsis thaliana)
- Transmembrane protein, putative (duf3317) (9 kDa, Protein from Arabidopsis thaliana)
- Atlcb1 (46 kDa, Protein from Arabidopsis thaliana)
Cryo-EM structure of the monomeric atSPT-ORM1 (ORM1-N17A) complex
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7yjn
Q-score: 0.526
Liu P, Xie T, Wu X, Han G, Gupta SD, Zhang Z, Yue J, Dong F, Gable K, Niranjanakumari S, Li W, Wang L, Liu W, Yao R, Cahoon EB, Dunn TM, Gong X
Sci Adv (2023) 9 pp. eadg0728-eadg0728 [ DOI: doi:10.1126/sciadv.adg0728 Pubmed: 36989369 ]
- Long chain base biosynthesis protein 1 (6 kDa, Protein from Arabidopsis thaliana)
- Long chain base biosynthesis protein 1 (46 kDa, Protein from Arabidopsis thaliana)
- Pyridoxal-5'-phosphate (247 Da, Ligand)
- Long chain base biosynthesis protein 2a (54 kDa, Protein from Arabidopsis thaliana)
- Ormdl family protein (18 kDa, Protein from Arabidopsis thaliana)
- Spt-orm1 complex (Complex from Arabidopsis thaliana)
- Transmembrane protein, putative (duf3317) (9 kDa, Protein from Arabidopsis thaliana)
Cryo-EM structure of the monomeric atSPT-ORM1 (LCB2a-deltaN5) complex
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7yjo
Q-score: 0.621
Liu P, Xie T, Wu X, Han G, Gupta SD, Zhang Z, Yue J, Dong F, Gable K, Niranjanakumari S, Li W, Wang L, Liu W, Yao R, Cahoon EB, Dunn TM, Gong X
Sci Adv (2023) 9 pp. eadg0728-eadg0728 [ DOI: doi:10.1126/sciadv.adg0728 Pubmed: 36989369 ]
- Ormdl family protein (18 kDa, Protein from Arabidopsis thaliana)
- Long chain base biosynthesis protein 2a (53 kDa, Protein from Arabidopsis thaliana)
- Atlcb1 (6 kDa, Protein from Arabidopsis thaliana)
- N-[(2s,3r,4e)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide (650 Da, Ligand)
- Spt-orm1 complex (Complex from Arabidopsis thaliana)
- Transmembrane protein, putative (duf3317) (9 kDa, Protein from Arabidopsis thaliana)
- Atlcb1 (46 kDa, Protein from Arabidopsis thaliana)
- [3-hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-ylmethyl]-serine (336 Da, Ligand)
Resolution: 2.27 Å
EM Method: Single-particle
Fitted PDBs: 8fq4
Q-score: 0.693
Mietzsch M, Liu W, Ma K, Bennett A, Nelson AR, Gliwa K, Chipman P, Fu X, Bechler S, McKenna R, Viner R
Mol Ther Methods Clin Dev (2023) 29 pp. 460-472 [ Pubmed: 37273903 DOI: doi:10.1016/j.omtm.2023.05.002 ]
- Adeno-associated virus - 1 (3 MDa, Virus from Adeno-associated virus - 1)
- Capsid protein (58 kDa, Protein from Adeno-associated virus - 1)