Structural Basis of Human NOX5 Activation
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8u85
Q-score: 0.502
Cui C, Jiang M, Jain N, Das S, Lo YH, Kermani AA, Pipatpolkai T, Sun J
Nat Commun (2024) 15 pp. 3994-3994 [ DOI: doi:10.1038/s41467-024-48467-y Pubmed: 38734761 ]
- 1,2-dilauroyl-sn-glycero-3-phosphate (535 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Nadph oxidase 5 (82 kDa, Protein from Homo sapiens)
- Ala-ala-ala-ala-ala-ala-ala-ala-ala-ala-ala-ala-ala (942 Da, Protein from Homo sapiens)
- Nadph oxidase 5 (Complex from Homo sapiens)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Heme b/c (618 Da, Ligand)
- Flavin-adenine dinucleotide (785 Da, Ligand)
Structural Basis of Human NOX5 Activation
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8u86
Q-score: 0.45
Cui C, Jiang M, Jain N, Das S, Lo YH, Kermani AA, Pipatpolkai T, Sun J
Nat Commun (2024) 15 pp. 3994-3994 [ DOI: doi:10.1038/s41467-024-48467-y Pubmed: 38734761 ]
- Zinc ion (65 Da, Ligand)
- Nadph oxidase 5 (82 kDa, Protein from Homo sapiens)
- Nadph oxidase 5 (Complex from Homo sapiens)
- Decane (142 Da, Ligand)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Heme b/c (618 Da, Ligand)
- Flavin-adenine dinucleotide (785 Da, Ligand)
- Dodecane (170 Da, Ligand)
Structural Basis of Human NOX5 Activation
Resolution: 3.86 Å
EM Method: Single-particle
Fitted PDBs: 8u87
Q-score: 0.432
Cui C, Jiang M, Jain N, Das S, Lo YH, Kermani AA, Pipatpolkai T, Sun J
Nat Commun (2024) 15 pp. 3994-3994 [ DOI: doi:10.1038/s41467-024-48467-y Pubmed: 38734761 ]
- Zinc ion (65 Da, Ligand)
- Nadph oxidase 5 (82 kDa, Protein from Homo sapiens)
- Nadph oxidase 5 (Complex from Homo sapiens)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Heme b/c (618 Da, Ligand)
- Flavin-adenine dinucleotide (785 Da, Ligand)
- Dodecane (170 Da, Ligand)
Structural Basis of Human NOX5 Activation
Resolution: 4.06 Å
EM Method: Single-particle
Fitted PDBs: 8u7y
Q-score: 0.327
Cui C, Jiang M, Jain N, Das S, Lo YH, Kermani AA, Pipatpolkai T, Sun J
Nat Commun (2024) 15 pp. 3994-3994 [ DOI: doi:10.1038/s41467-024-48467-y Pubmed: 38734761 ]
- Zinc ion (65 Da, Ligand)
- Nadph oxidase 5 (82 kDa, Protein from Homo sapiens)
- Nadp nicotinamide-adenine-dinucleotide phosphate (743 Da, Ligand)
- Nadph oxidase 5 (Complex from Homo sapiens)
- Decane (142 Da, Ligand)
- Heme b/c (618 Da, Ligand)
- Flavin-adenine dinucleotide (785 Da, Ligand)
- Dodecane (170 Da, Ligand)
Resolution: 3.73 Å
EM Method: Single-particle
Fitted PDBs: 8dws
Q-score: 0.223
Cuneo MJ, O'Flynn BG, Lo YH, Sabri N, Mittag T
Mol Cell (2023) 83 pp. 731-745.e4 [ Pubmed: 36693379 DOI: doi:10.1016/j.molcel.2022.12.033 ]
- Speckle-type poz protein (42 kDa, Protein from Homo sapiens)
- Spop e47k mutant (Complex from Homo sapiens)
Resolution: 6.2 Å
EM Method: Single-particle
Fitted PDBs: 8dwt
Q-score: 0.168
Cuneo MJ, O'Flynn BG, Lo YH, Sabri N, Mittag T
Mol Cell (2023) 83 pp. 731-745.e4 [ Pubmed: 36693379 DOI: doi:10.1016/j.molcel.2022.12.033 ]
- Spop w22r mutant (tetrameric form) (Complex from Homo sapiens)
- Speckle-type poz protein (42 kDa, Protein from Homo sapiens)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8dwu
Q-score: 0.284
Cuneo MJ, O'Flynn BG, Lo YH, Sabri N, Mittag T
Mol Cell (2023) 83 pp. 731-745.e4 [ Pubmed: 36693379 DOI: doi:10.1016/j.molcel.2022.12.033 ]
- Water (18 Da, Ligand)
- Speckle-type poz protein (42 kDa, Protein from Homo sapiens)
- Spop e47k mutant (Complex from Homo sapiens)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8dwv
Q-score: 0.23
Cuneo MJ, O'Flynn BG, Lo YH, Sabri N, Mittag T
Mol Cell (2023) 83 pp. 731-745.e4 [ Pubmed: 36693379 DOI: doi:10.1016/j.molcel.2022.12.033 ]
- Speckle-type poz protein (42 kDa, Protein from Homo sapiens)
- Spop e47k mutant (Complex from Homo sapiens)
Human Kv4.2-KChIP2 channel complex in an open state, transmembrane region
Human Kv4.2-KChIP2 channel complex in an inactivated state, class 1, transmembrane region