Structure of interleukin receptor common gamma chain (IL2Rgamma/CD132) in complex with 2D4
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 9jqt
Q-score: 0.555
Yin H, Li L, Feng X, Wang Z, Zheng M, Zhao J, Fan X, Wu W, Gao L, Zhan Y, Zhao M, Lu Q
Signal Transduct Target Ther (2024) 9 pp. 323-323 [ Pubmed: 39551768 DOI: doi:10.1038/s41392-024-02017-6 ]
- Anti-fab nanobody (14 kDa, Protein from Lama glama)
- Interleukin receptor common gamma chain (il2rgamma/cd132) in complex with 2d4 (Complex from Homo sapiens)
- Cytokine receptor common subunit gamma (28 kDa, Protein from Homo sapiens)
- 2d4-light chain (23 kDa, Protein from Homo sapiens)
- 2d4-heavy chain (23 kDa, Protein from Homo sapiens)
Cryo-EM structure of human HCN3 channel with cAMP
Resolution: 3.19 Å
EM Method: Single-particle
Fitted PDBs: 8io0
Q-score: 0.42
Cryo-EM structure of CRISPR-Csm effector complex from Mycobacterium canettii
Resolution: 3.73 Å
EM Method: Single-particle
Fitted PDBs: 8wfx
Q-score: 0.39
Zhang H, Shi M, Ma X, Liu M, Wang N, Lu Q, Li Z, Zhao Y, Zhao H, Chen H, Zhang H, Jiang T, Ouyang S, Huo Y, Bi L
Int J Biol Macromol (2024) 260 pp. 129331-129331 [ DOI: doi:10.1016/j.ijbiomac.2024.129331 Pubmed: 38218299 ]
- Crispr system cms protein csm2 (15 kDa, Protein from Mycobacterium canettii)
- Crispr system cms protein csm4 (32 kDa, Protein from Mycobacterium canettii)
- Crispr system cms endoribonuclease csm3 (25 kDa, Protein from Mycobacterium canettii)
- Crispr system single-strand-specific deoxyribonuclease cas10/csm1 (subtype iii-a) (91 kDa, Protein from Mycobacterium canettii)
- Rna (50-mer) (16 kDa, RNA from Mycobacterium canettii)
- Csm effector complex (Complex from Mycobacterium canettii)
- Crispr system cms protein csm5 (42 kDa, Protein from Mycobacterium canettii)
Cryo-EM structure of human HCN3 channel in apo state
Resolution: 2.72 Å
EM Method: Single-particle
Fitted PDBs: 8inz
Q-score: 0.526
Yu B, Lu Q, Li J, Cheng X, Hu H, Li Y, Che T, Hua Y, Jiang H, Zhang Y, Xian C, Yang T, Fu Y, Chen Y, Nan W, McCormick PJ, Xiong B, Duan J, Zeng B, Li Y, Fu Y, Zhang J
J Biol Chem (2024) 300 pp. 107288-107288 [ DOI: doi:10.1016/j.jbc.2024.107288 Pubmed: 38636662 ]
- 4-[[(2~{s},4~{a}~{r},6~{s},8~{a}~{s})-6-[(4~{s},5~{r})-4-[(2~{s})-butan-2-yl]-5,9-dimethyl-decyl]-4~{a}-methyl-2,3,4,5,6,7,8,8~{a}-octahydro-1~{h}-naphthalen-2-yl]oxy]-4-oxidanylidene-butanoic acid (492 Da, Ligand)
- Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Complex from Homo sapiens)
- Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (86 kDa, Protein from Homo sapiens)
The cryo-EM structure of the Mycobacterium tuberculosis CRISPR-Csm complex
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8x5d
Q-score: 0.547
Zhang H, Shi M, Ma X, Liu M, Wang N, Lu Q, Li Z, Zhao Y, Zhao H, Chen H, Zhang H, Jiang T, Ouyang S, Huo Y, Bi L
Int J Biol Macromol (2024) 260 pp. 129331-129331 [ DOI: doi:10.1016/j.ijbiomac.2024.129331 Pubmed: 38218299 ]
- Csm2 (15 kDa, Protein from Mycobacterium canettii)
- Mycobacteria crispr-csm complexes (Complex from Mycobacterium tuberculosis)
- Csm2 (Complex from Mycobacterium canettii)
- Rna (47-mer) (59 kDa, RNA from Mycobacterium tuberculosis)
- Crispr system cms endoribonuclease csm3 (26 kDa, Protein from Mycobacterium tuberculosis)
- Crispr system cms protein csm5 (42 kDa, Protein from Mycobacterium tuberculosis)
Cryo-EM structure of Cas12g-sgRNA binary complex
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8i3q
Q-score: 0.461
Liu M, Li Z, Chen J, Lin J, Lu Q, Ye Y, Zhang H, Zhang B, Ouyang S
PLoS Genet (2023) 19 pp. e1010930-e1010930 [ DOI: doi:10.1371/journal.pgen.1010930 Pubmed: 37729124 ]
- Cas12g (89 kDa, Protein from Escherichia coli)
- Cas12g-sgrna binary complex (Complex from Escherichia coli)
- Rna (139-mer) (44 kDa, RNA from Escherichia coli)
- Zinc ion (65 Da, Ligand)
- Cas12g (Complex)
- Rna (Complex)
Cryo-EM structure of E. coli RNAP sigma32 complex
Resolution: 2.49 Å
EM Method: Single-particle
Fitted PDBs: 8hkc
Q-score: 0.582
Lu Q, Chen T, Wang J, Wang F, Ye W, Ma L, Wu S
Biomolecules (2023) 13 [ DOI: doi:10.3390/biom13050738 Pubmed: 37238608 ]
- Dna-directed rna polymerase subunit beta' (157 kDa, Protein from Escherichia coli K-12)
- Dna-directed rna polymerase subunit beta (151 kDa, Protein from Escherichia coli K-12)
- Dna (54-mer) (16 kDa, DNA from Escherichia coli)
- Rna polymerase sigma factor rpoh (32 kDa, Protein from Escherichia coli K-12)
- Magnesium ion (24 Da, Ligand)
- Dna (54-mer) (16 kDa, DNA from Escherichia coli)
- Dna-directed rna polymerase subunit alpha (36 kDa, Protein from Escherichia coli K-12)
- Cryo-em structure of e. coli rnap sigma32 complex (Complex from Escherichia coli K-12)
- Zinc ion (65 Da, Ligand)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8if8
Q-score: 0.552
Gong Y, Wei C, Wang J, Mu N, Lu Q, Wu C, Yan N, Yang H, Zhao Y, Yang X, Gurcha SS, Veerapen N, Batt SM, Hao Z, Da L, Besra GS, Rao Z, Zhang L
PNAS (2023) 120 pp. e2302858120-e2302858120 [ DOI: doi:10.1073/pnas.2302858120 Pubmed: 37252995 ]
- Galactan 5-o-arabinofuranosyltransferase (69 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Afta dimer (69 kDa, Complex from Mycobacterium tuberculosis H37Rv)
- Calcium ion (40 Da, Ligand)
Structure of an orphan GPCR-G protein signaling complex
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7wz4
Q-score: 0.523
Chen G, Xu J, Inoue A, Schmidt MF, Bai C, Lu Q, Gmeiner P, Liu Z, Du Y
Nat Commun (2022) 13 pp. 2375-2375 [ DOI: doi:10.1038/s41467-022-30081-5 Pubmed: 35501348 ]
- Scfv16 (Complex from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Probable g-protein coupled receptor 88 (55 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Scfv16 (27 kDa, Protein from Mus musculus)
- Gpr88-gi1 signaling complex (Complex)
- Gpr88-gi1 (Complex from Homo sapiens)
Structure of the alpha2A-adrenergic receptor GoA signaling complex
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7ej0
Q-score: 0.426
Xu J, Cao S, Hubner H, Weikert D, Chen G, Lu Q, Yuan D, Gmeiner P, Liu Z, Du Y
Sci Adv (2022) 8 pp. eabj5347-eabj5347 [ Pubmed: 35245122 DOI: doi:10.1126/sciadv.abj5347 ]
- Scfv16 (32 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Alpha-2a adrenergic receptor (50 kDa, Protein from Homo sapiens)
- Noradrenaline (170 Da, Ligand)
- Alpha2a-adrenergic receptor go signaling complex (Complex)
- Scfv16 (Complex from Mus musculus)
- Alpha2a-adrenergic receptor go signaling complex (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(o) subunit alpha (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)