Cryo-EM structure of peptide free and Gs-coupled GIPR
Resolution: 2.86 Å
EM Method: Single-particle
Fitted PDBs: 8wa3
Q-score: 0.464
Cong Z, Zhao F, Li Y, Luo G, Mai Y, Chen X, Chen Y, Lin S, Cai X, Zhou Q, Yang D, Wang MW
Cell Discov (2024) 10 pp. 18-18 [ Pubmed: 38346960 DOI: doi:10.1038/s41421-024-00649-0 ]
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (45 kDa, Protein from Bos taurus)
- Gastric inhibitory polypeptide receptor,fusion protein (64 kDa, Protein from Homo sapiens)
- Cryo-em structure of the human glucose-dependent insulinotropic polypeptide receptor in complex with gip and g protein (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1,o-antigen polymerase (40 kDa, Protein from Leptolinea tardivitalis)
- Nanobody-35 (15 kDa, Protein from synthetic construct)
Cryo-EM structures of peptide free and Gs-coupled GLP-1R
Resolution: 2.54 Å
EM Method: Single-particle
Fitted PDBs: 8wg7
Q-score: 0.513
Cong Z, Zhao F, Li Y, Luo G, Mai Y, Chen X, Chen Y, Lin S, Cai X, Zhou Q, Yang D, Wang MW
Cell Discov (2024) 10 pp. 18-18 [ Pubmed: 38346960 DOI: doi:10.1038/s41421-024-00649-0 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (40 kDa, Protein from Rattus norvegicus)
- Cryo-em structure of the human glucagon like peptide 1 receptor in complex with tirzepatide and g protein (Complex from Homo sapiens)
- Glucagon-like peptide 1 receptor (50 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (45 kDa, Protein from Homo sapiens)
- Nanobody-35 (13 kDa, Protein from synthetic construct)
Cryo-EM structures of peptide free and Gs-coupled GCGR
Resolution: 2.71 Å
EM Method: Single-particle
Fitted PDBs: 8wg8
Q-score: 0.498
Cong Z, Zhao F, Li Y, Luo G, Mai Y, Chen X, Chen Y, Lin S, Cai X, Zhou Q, Yang D, Wang MW
Cell Discov (2024) 10 pp. 18-18 [ Pubmed: 38346960 DOI: doi:10.1038/s41421-024-00649-0 ]
- Pro-pro-pro-pro-phe-ser-asn-leu-val-met-asp-asp-leu-lys-asn-lys-lys (1 kDa, Protein from Spodoptera frugiperda)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (40 kDa, Protein from Rattus norvegicus)
- Cryo-em structure of the human glucagon like peptide 1 receptor in complex with tirzepatide and g protein (Complex from Homo sapiens)
- Glucagon receptor (46 kDa, Protein from Homo sapiens)
- Nanobody-35 (15 kDa, Protein from synthetic construct)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (41 kDa, Protein from Homo sapiens)
Resolution: 2.12 Å
EM Method: Single-particle
Fitted PDBs: 7xy9
Q-score: 0.714
Chen Q, Qu G, Li X, Feng M, Yang F, Li Y, Li J, Tong F, Song S, Wang Y, Sun Z, Luo G
Nat Commun (2023) 14 pp. 2117-2117 [ DOI: doi:10.1038/s41467-023-37921-y Pubmed: 37055470 ]
- Enzyme assembled gel (Complex from Thermoanaerobacter brockii)
- Water (18 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Nadp-dependent isopropanol dehydrogenase (38 kDa, Protein from Thermoanaerobacter brockii)
- Zinc ion (65 Da, Ligand)
Cryo-EM Structure of the Exocyst Complex
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 5yfp
Q-score: 0.155
Mei K, Li Y, Wang S, Shao G, Wang J, Ding Y, Luo G, Yue P, Liu JJ, Wang X, Dong MQ, Wang HW, Guo W
Nat Struct Mol Biol (2018) 25 pp. 139-146 [ Pubmed: 29335562 DOI: doi:10.1038/s41594-017-0016-2 ]
- Exocyst complex component sec15 (105 kDa, Protein from Saccharomyces cerevisia S288c)
- Exocyst complex component exo84 (85 kDa, Protein from Saccharomyces cerevisiae S288c)
- Exocyst complex component sec10 (100 kDa, Protein from Saccharomyces cerevisia S288c)
- Exocyst complex component sec5 (112 kDa, Protein from Saccharomyces cerevisia S288c)
- Exocyst complex component sec6 (93 kDa, Protein from Saccharomyces cerevisia S288c)
- Exocyst complex component exo70 (71 kDa, Protein from Saccharomyces cerevisia S288c)
- Exocyst complex component sec3 (154 kDa, Protein from Saccharomyces cerevisiae S288c)
- Cryo-em map of the yeast exocyst complex overall structure at 5.5a resolution (844 kDa, Complex from Saccharomyces cerevisia S288c)
- Exocyst complex component sec8 (122 kDa, Protein from Saccharomyces cerevisia S288c)