AK-42 inhibitor binding human ClC-2 TMD
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8gqu
Q-score: 0.377
Ma T, Wang L, Chai A, Liu C, Cui W, Yuan S, Wing Ngor Au S, Sun L, Zhang X, Zhang Z, Lu J, Gao Y, Wang P, Li Z, Liang Y, Vogel H, Wang YT, Wang D, Yan K, Zhang H
Nat Commun (2023) 14 pp. 3424-3424 [ Pubmed: 37296152 DOI: doi:10.1038/s41467-023-39218-6 ]
- 2-[[2,6-bis(chloranyl)-3-phenylmethoxy-phenyl]amino]pyridine-3-carboxylic acid (389 Da, Ligand)
- Ak-42 inhibitor binding human clc-2 tmd 3.5a (180 MDa, Complex from Homo sapiens)
- Chloride channel protein 2 (98 kDa, Protein from Homo sapiens)
TMD masked refine map of human ClC-2
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7xja
Q-score: 0.372
Ma T, Wang L, Chai A, Liu C, Cui W, Yuan S, Wing Ngor Au S, Sun L, Zhang X, Zhang Z, Lu J, Gao Y, Wang P, Li Z, Liang Y, Vogel H, Wang YT, Wang D, Yan K, Zhang H
Nat Commun (2023) 14 pp. 3424- [ DOI: doi:10.1038/s41467-023-39218-6 ]
- Full length human clc-2 homo dimer (180 MDa, Complex from Homo sapiens)
- Chloride channel protein 2 (98 kDa, Protein from Homo sapiens)
Full length human CLC-2 channel in apo state
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7xf5
Q-score: 0.258
Ma T, Wang L, Chai A, Liu C, Cui W, Yuan S, Wing Ngor Au S, Sun L, Zhang X, Zhang Z, Lu J, Gao Y, Wang P, Li Z, Liang Y, Vogel H, Wang YT, Wang D, Yan K, Zhang H
Nat Commun (2023) 14 pp. 3424- [ DOI: doi:10.1038/s41467-023-39218-6 ]
- Full length human clc-2 homo dimer (180 MDa, Complex from Homo sapiens)
- Chloride channel protein 2 (98 kDa, Protein from Homo sapiens)
Human phosphofructokinase-1 liver type bound to activator NA-11
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7lw1
Q-score: 0.543
Amara N, Cooper MP, Voronkova MA, Webb BA, Lynch EM, Kollman JM, Ma T, Yu K, Lai Z, Sangaraju D, Kayagaki N, Newton K, Bogyo M, Staben ST, Dixit VM
Cell (2021) 184 pp. 4480-4494.e15 [ Pubmed: 34320407 DOI: doi:10.1016/j.cell.2021.07.004 ]
- 1,6-di-o-phosphono-beta-d-fructofuranose (340 Da, Ligand)
- N-{(11s)-2-[2-(5-hydroxypent-1-yn-1-yl)phenyl]-4h,10h-pyrazolo[5,1-c][1,4]benzoxazepin-7-yl}acetamide (401 Da, Ligand)
- Atp-dependent 6-phosphofructokinase, liver type (85 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Human phosphofructokinase-1 liver type bound to activator na-11 (Complex from Homo sapiens)
- 6-o-phosphono-beta-d-fructofuranose (260 Da, Ligand)
Zika virus complexed with a neutralizing antibody Z23-Fab
Resolution: 9.4 Å
EM Method: Single-particle
Fitted PDBs: 5gzr
Q-score: 0.102
Wang Q, Yang H, Liu X, Dai L, Ma T, Qi J, Wong G, Peng R, Liu S, Li J, Li S, Song J, Liu J, He J, Yuan H, Xiong Y, Liao Y, Li J, Yang J, Tong Z, Griffin BD, Bi Y, Liang M, Xu X, Qin C, Cheng G, Zhang X, Wang P, Qiu X, Kobinger G, Shi Y, Yan J, Gao GF
Sci Transl Med (2016) 8 pp. 369ra179-369ra179 [ DOI: doi:10.1126/scitranslmed.aai8336 Pubmed: 27974667 ]
- Strutural protein m (8 kDa, Protein from Zika virus)
- Structural protein e (54 kDa, Protein from Zika virus)
- Zika virus in complex with a neutralizing antibody z23 fab (Complex)
- Z23 fab heavy chain (23 kDa, Protein from Homo sapiens)
- Zika virus (Complex from Zika virus)
- Z23 fab light chain (23 kDa, Protein from Homo sapiens)
- Neutralizing antibody z23 fab (Complex)