Resolution: 2.74 Å
EM Method: Single-particle
Fitted PDBs: 8smv
Q-score: 0.572
Hoppe N, Harrison S, Hwang SH, Chen Z, Karelina M, Deshpande I, Suomivuori CM, Palicharla VR, Berry SP, Tschaikner P, Regele D, Covey DF, Stefan E, Marks DS, Reiter JF, Dror RO, Evers AS, Mukhopadhyay S, Manglik A
Nat Struct Mol Biol (2024) 31 pp. 667-677 [ DOI: doi:10.1038/s41594-024-01223-8 Pubmed: 38326651 ]
- Nanobody 35 (15 kDa, Protein from Lama glama)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (40 kDa, Protein from Homo sapiens)
- G-protein coupled receptor 161, guanine nucleotide-binding protein g(s) subunit alpha isoforms short (Complex from Homo sapiens)
- Gpr161 gs heterotrimeric complex with nb35 (Complex)
- Nanobody 35 (Complex from Lama glama)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2, guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (Complex from Homo sapiens)
- G-protein coupled receptor 161 (59 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (30 kDa, Protein from Homo sapiens)
Cryo-EM map of the full-length relaxin receptor RXFP1 in complex with heterotrimeric Gs
Erlandson SC, Rawson S, Osei-Owusu J, Brock KP, Liu X, Paulo JA, Mintseris J, Gygi SP, Marks DS, Cong X, Kruse AC
Nat Chem Biol (2023) 19 pp. 1013-1021 [ DOI: doi:10.1038/s41589-023-01321-6 Pubmed: 37081311 ]
- Camelid antibody vhh fragment nb35 (Complex from Lama glama)
- Complex of the relaxin receptor rxfp1 and heterotrimeric gs (180 kDa, Complex)
- Camelid antibody vhh fragment nb35 (Protein from Lama glama)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (Protein from Homo sapiens)
- Relaxin receptor 1, guanine nucleotide-binding protein g(s) subunit alpha isoforms short fusion (Protein from Homo sapiens)
- Relaxin receptor 1, guanine nucleotide-binding protein g(s) subunit alpha isoforms short (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1, guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (Protein from Homo sapiens)
Cryo-EM structure of the relaxin receptor RXFP1 in complex with heterotrimeric Gs
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7tmw
Q-score: 0.336
Erlandson SC, Rawson S, Osei-Owusu J, Brock KP, Liu X, Paulo JA, Mintseris J, Gygi SP, Marks DS, Cong X, Kruse AC
Nat Chem Biol (2023) 19 pp. 1013-1021 [ DOI: doi:10.1038/s41589-023-01321-6 Pubmed: 37081311 ]
- Relaxin receptor 1, guanine nucleotide-binding protein g(s) subunit alpha isoforms short fusion (Complex from Homo sapiens)
- Camelid antibody vhh fragment nb35 (Complex from Lama glama)
- Relaxin receptor 1, guanine nucleotide-binding protein g(s) subunit alpha isoforms short fusion (113 kDa, Protein from Homo sapiens)
- Complex of the relaxin receptor rxfp1 and heterotrimeric gs (180 kDa, Complex)
- Camelid antibody vhh fragment nb35 (17 kDa, Protein from Lama glama)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1, guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
Cryo-EM structure of lipid droplet formation protein Seipin/BSCL2
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6mlu
Q-score: 0.338
Sui X, Arlt H, Brock KP, Lai ZW, DiMaio F, Marks DS, Liao M, Farese Jr RV, Walther TC
J Cell Biol (2018) 217 pp. 4080-4091 [ DOI: doi:10.1083/jcb.201809067 Pubmed: 30327422 ]
- Cryo-em protein structure of seipin/bscl2 (43 MDa, Cellular component from Drosophila melanogaster)
- Seipin (43 kDa, Protein from Drosophila melanogaster)