BG505 SOSIP.v5.2 in complex with VRC40.01 and RM19R Fabs
Resolution: 3.28 Å
EM Method: Single-particle
Fitted PDBs: 7lg6
Q-score: 0.484
Cottrell CA, Manne K, Kong R, Wang S, Zhou T, Chuang GY, Edwards RJ, Henderson R, Janowska K, Kopp M, Lin BC, Louder MK, Olia AS, Rawi R, Shen CH, Taft JD, Torres JL, Wu NR, Zhang B, Doria-Rose NA, Cohen MS, Haynes BF, Shapiro L, Ward AB, Acharya P, Mascola JR, Kwong PD
Cell Rep (2021) 37 pp. 109922-109922 [ DOI: doi:10.1016/j.celrep.2021.109922 Pubmed: 34731616 ]
- Rm19r fab (Complex from Macaca mulatta)
- Rm19r fab kappa light chain (23 kDa, Protein from Macaca mulatta)
- Vrc40.01 fab heavy chain (24 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp120 (53 kDa, Protein from Human immunodeficiency virus 1)
- Bg505 sosip.v5.2 (Complex from Human immunodeficiency virus 1)
- Bg505 sosip.v5.2 in complex with vrc40.01 and rm19r fabs (Complex)
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Vrc40.01 fab kappa light chain (23 kDa, Protein from Homo sapiens)
- Vrc40.01 fab (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Rm19r fab heavy chain (23 kDa, Protein from Macaca mulatta)
Resolution: 4.8 Å
EM Method: Single-particle
Fitted PDBs: 7llk
Q-score: 0.236
Cottrell CA, Manne K, Kong R, Wang S, Zhou T, Chuang GY, Edwards RJ, Henderson R, Janowska K, Kopp M, Lin BC, Louder MK, Olia AS, Rawi R, Shen CH, Taft JD, Torres JL, Wu NR, Zhang B, Doria-Rose NA, Cohen MS, Haynes BF, Shapiro L, Ward AB, Acharya P, Mascola JR, Kwong PD
Cell Rep (2021) 37 pp. 109922-109922 [ DOI: doi:10.1016/j.celrep.2021.109922 Pubmed: 34731616 ]
- 179nc75 fab heavy chain (25 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Trimeric hiv-1 env in complex with vrc33.01 fab (Complex from Human immunodeficiency virus 1)
- Envelope glycoprotein gp120 (53 kDa, Protein from Human immunodeficiency virus 1)
- 179nc75 fab light chain (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.73 Å
EM Method: Single-particle
Fitted PDBs: 7ll1
Q-score: 0.414
Cottrell CA, Manne K, Kong R, Wang S, Zhou T, Chuang GY, Edwards RJ, Henderson R, Janowska K, Kopp M, Lin BC, Louder MK, Olia AS, Rawi R, Shen CH, Taft JD, Torres JL, Wu NR, Zhang B, Doria-Rose NA, Cohen MS, Haynes BF, Shapiro L, Ward AB, Acharya P, Mascola JR, Kwong PD
Cell Rep (2021) 37 pp. 109922-109922 [ DOI: doi:10.1016/j.celrep.2021.109922 Pubmed: 34731616 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Vrc40.01 fab heavy chain (24 kDa, Protein from Homo sapiens)
- Vrc40.01 fab light chain (23 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp120 (52 kDa, Protein from Human immunodeficiency virus 1)
- Trimer hiv-1 env in complex with vrc40.01 fab (Complex from Human immunodeficiency virus 1)
Resolution: 3.73 Å
EM Method: Single-particle
Fitted PDBs: 7ll2
Q-score: 0.424
Cottrell CA, Manne K, Kong R, Wang S, Zhou T, Chuang GY, Edwards RJ, Henderson R, Janowska K, Kopp M, Lin BC, Louder MK, Olia AS, Rawi R, Shen CH, Taft JD, Torres JL, Wu NR, Zhang B, Doria-Rose NA, Cohen MS, Haynes BF, Shapiro L, Ward AB, Acharya P, Mascola JR, Kwong PD
Cell Rep (2021) 37 pp. 109922-109922 [ Pubmed: 34731616 DOI: doi:10.1016/j.celrep.2021.109922 ]
- Vrc33.01 fab light chain (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Envelope glycoprotein gp120 (52 kDa, Protein from Human immunodeficiency virus 1)
- Vrc33.01 fab heavy chain (24 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Trimeric hiv-1 env in complex with vrc33.01 fab (Complex from Human immunodeficiency virus 1)
Dubrovskaya V, Tran K, Ozorowski G, Guenaga J, Wilson R, Bale S, Cottrell CA, Turner HL, Seabright G, O'Dell S, Torres JL, Yang L, Feng Y, Leaman DP, Vazquez Bernat N, Liban T, Louder M, McKee K, Bailer RT, Movsesyan A, Doria-Rose NA, Pancera M, Karlsson Hedestam GB, Zwick MB, Crispin M, Mascola JR, Ward AB, Wyatt RT
Immunity (2019) 51 pp. 915-929.e7 [ Pubmed: 31732167 DOI: doi:10.1016/j.immuni.2019.10.008 ]
HIV Env BG505 NFL TD+ in complex with antibody E70 fragment antigen binding
Resolution: 3.57 Å
EM Method: Single-particle
Fitted PDBs: 6p62
Q-score: 0.453
Dubrovskaya V, Tran K, Ozorowski G, Guenaga J, Wilson R, Bale S, Cottrell CA, Turner HL, Seabright G, O'Dell S, Torres JL, Yang L, Feng Y, Leaman DP, Vazquez Bernat N, Liban T, Louder M, McKee K, Bailer RT, Movsesyan A, Doria-Rose NA, Pancera M, Karlsson Hedestam GB, Zwick MB, Crispin M, Mascola JR, Ward AB, Wyatt RT
Immunity (2019) 51 pp. 915-929.e7 [ DOI: doi:10.1016/j.immuni.2019.10.008 Pubmed: 31732167 ]
- Hiv-1 env bg505 nfl td+ (74 kDa, Protein from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Hiv-1 env bg505 nfl td+ in complex with rabbit monoclonal antibody e70 fragment antigen binding (570 kDa, Complex from Human immunodeficiency virus 1)
- Rabbit monoclonal antibody e70 heavy chain fragment antigen binding (23 kDa, Protein from Oryctolagus cuniculus)
- Rabbit monoclonal antibody e70 kappa chain (22 kDa, Protein from Oryctolagus cuniculus)
HIV Env 16055 NFL TD 2CC+ in complex with antibody 1C2 fragment antigen binding
Resolution: 3.94 Å
EM Method: Single-particle
Fitted PDBs: 6p65
Q-score: 0.388
Dubrovskaya V, Tran K, Ozorowski G, Guenaga J, Wilson R, Bale S, Cottrell CA, Turner HL, Seabright G, O'Dell S, Torres JL, Yang L, Feng Y, Leaman DP, Vazquez Bernat N, Liban T, Louder M, McKee K, Bailer RT, Movsesyan A, Doria-Rose NA, Pancera M, Karlsson Hedestam GB, Zwick MB, Crispin M, Mascola JR, Ward AB, Wyatt RT
Immunity (2019) 51 pp. 915-929.e7 [ Pubmed: 31732167 DOI: doi:10.1016/j.immuni.2019.10.008 ]
- Rabbit antibody 1c2 heavy chain fragment antigen binding (27 kDa, Protein from Oryctolagus cuniculus)
- Rabbit antibody 1c2 kappa chain (25 kDa, Protein from Oryctolagus cuniculus)
- Hiv env 16055 nfl td 2cc+ in complex with antibody 1c2 fragment antigen binding (570 kDa, Complex from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Hiv env 16055 nfl td 2cc+ (75 kDa, Protein from Human immunodeficiency virus 1)
Dubrovskaya V, Tran K, Ozorowski G, Guenaga J, Wilson R, Bale S, Cottrell CA, Turner HL, Seabright G, O'Dell S, Torres JL, Yang L, Feng Y, Leaman DP, Vazquez Bernat N, Liban T, Louder M, McKee K, Bailer RT, Movsesyan A, Doria-Rose NA, Pancera M, Karlsson Hedestam GB, Zwick MB, Crispin M, Mascola JR, Ward AB, Wyatt RT
Immunity (2019) 51 pp. 915-929.e7 [ Pubmed: 31732167 DOI: doi:10.1016/j.immuni.2019.10.008 ]
- Hiv-1 env bg505 nfl cc+ trimer (Protein from Human immunodeficiency virus 1)
- Rabbit antibody e70 fragment antigen binding heavy chain (Protein from Oryctolagus cuniculus)
- Hiv-1 env bg505 nfl cc+ trimer in complex with rabbit antibody e70 fragment antigen binding (570 kDa, Complex)
- Rabbit antibody e70 fragment antigen binding kappa chain (Protein from Oryctolagus cuniculus)
Dubrovskaya V, Tran K, Ozorowski G, Guenaga J, Wilson R, Bale S, Cottrell CA, Turner HL, Seabright G, O'Dell S, Torres JL, Yang L, Feng Y, Leaman DP, Vazquez Bernat N, Liban T, Louder M, McKee K, Bailer RT, Movsesyan A, Doria-Rose NA, Pancera M, Karlsson Hedestam GB, Zwick MB, Crispin M, Mascola JR, Ward AB, Wyatt RT
Immunity (2019) 51 pp. 915-929.e7 [ Pubmed: 31732167 DOI: doi:10.1016/j.immuni.2019.10.008 ]
- Hiv-1 env 16055 nfl td 2cc+ trimer (Protein from Human immunodeficiency virus 1)
- Rabbit antibody 1c2 fragment antigen binding heavy chain (Protein from Oryctolagus cuniculus)
- Hiv-1 env 16055 nfl td 2cc+ trimer in complex with rabbit antibody 1c2 fragment antigen binding (570 kDa, Complex)
- Rabbit antibody 1c2 fragment antigen binding kappa chain (Protein from Oryctolagus cuniculus)
Dubrovskaya V, Tran K, Ozorowski G, Guenaga J, Wilson R, Bale S, Cottrell CA, Turner HL, Seabright G, O'Dell S, Torres JL, Yang L, Feng Y, Leaman DP, Vazquez Bernat N, Liban T, Louder M, McKee K, Bailer RT, Movsesyan A, Doria-Rose NA, Pancera M, Karlsson Hedestam GB, Zwick MB, Crispin M, Mascola JR, Ward AB, Wyatt RT
Immunity (2019) 51 pp. 915-929.e7 [ Pubmed: 31732167 DOI: doi:10.1016/j.immuni.2019.10.008 ]