Cryo-EM structure of the magnesium channel CtMrs2 in the closed state
Resolution: 2.68 Å
EM Method: Single-particle
Fitted PDBs: 8q8p
Q-score: 0.55
Li P, Liu S, Wallerstein J, Villones RLE, Huang P, Lindkvist-Petersson K, Meloni G, Lu K, Steen Jensen K, Liin SI, Gourdon P
Nat Struct Mol Biol (2024) [ Pubmed: 39609652 DOI: doi:10.1038/s41594-024-01432-1 ]
- Mrs2 homo-pentamer (Complex from Thermochaetoides thermophila)
- Magnesium ion (24 Da, Ligand)
- Magnesium channel mrs2 (48 kDa, Protein from Thermochaetoides thermophila)
Cryo-EM structure of the magnesium channel CtMrs2 in the open state
Resolution: 3.22 Å
EM Method: Single-particle
Fitted PDBs: 8q8q
Q-score: 0.513
Li P, Liu S, Wallerstein J, Villones RLE, Huang P, Lindkvist-Petersson K, Meloni G, Lu K, Steen Jensen K, Liin SI, Gourdon P
Nat Struct Mol Biol (2024) [ Pubmed: 39609652 DOI: doi:10.1038/s41594-024-01432-1 ]
- (1r)-2-{[(r)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(dodecanoyloxy)methyl]ethyl (9z)-octadec-9-enoate (661 Da, Ligand)
- Mrs2 homo-pentamer (Complex from Thermochaetoides thermophila)
- Magnesium ion (24 Da, Ligand)
- Magnesium channel mrs2 (49 kDa, Protein from Thermochaetoides thermophila)
Structure of CtAtm1 in the inward-facing open conformation
Resolution: 3.08 Å
EM Method: Single-particle
Fitted PDBs: 7pqx
Q-score: 0.475
Li P, Hendricks AL, Wang Y, Villones RLE, Lindkvist-Petersson K, Meloni G, Cowan JA, Wang K, Gourdon P
Nat Commun (2022) 13 pp. 4339-4339 [ DOI: doi:10.1038/s41467-022-32006-8 Pubmed: 35896548 ]
Structure of CtAtm1 in the occluded conformation with ATP bound
Resolution: 2.81 Å
EM Method: Single-particle
Fitted PDBs: 7pr1
Q-score: 0.541
Li P, Hendricks AL, Wang Y, Villones RLE, Lindkvist-Petersson K, Meloni G, Cowan JA, Wang K, Gourdon P
Nat Commun (2022) 13 pp. 4339-4339 [ DOI: doi:10.1038/s41467-022-32006-8 Pubmed: 35896548 ]
- Putative iron-sulfur protein (77 kDa, Protein from Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719))
- Atm1 (Complex from Chaetomium thermophilum var. thermophilum DSM 1495)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
Structure of CtAtm1 in the inward-open with Glutathione-complexed [2Fe-2S] cluster bound
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7pro
Q-score: 0.482
Li P, Hendricks AL, Wang Y, Villones RLE, Lindkvist-Petersson K, Meloni G, Cowan JA, Wang K, Gourdon P
Nat Commun (2022) 13 pp. 4339-4339 [ DOI: doi:10.1038/s41467-022-32006-8 Pubmed: 35896548 ]
Structure of CtAtm1 in the inward-facing partially occluded with cargo bound
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7pru
Q-score: 0.441
Li P, Hendricks AL, Wang Y, Villones RLE, Lindkvist-Petersson K, Meloni G, Cowan JA, Wang K, Gourdon P
Nat Commun (2022) 13 pp. 4339-4339 [ DOI: doi:10.1038/s41467-022-32006-8 Pubmed: 35896548 ]
Structure of CtAtm1(E603Q) in the inward-facing open conformation
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7psd
Q-score: 0.499
Li P, Hendricks AL, Wang Y, Villones RLE, Lindkvist-Petersson K, Meloni G, Cowan JA, Wang K, Gourdon P
Nat Commun (2022) 13 pp. 4339-4339 [ DOI: doi:10.1038/s41467-022-32006-8 Pubmed: 35896548 ]
Cryo-EM structure of the full-length ABC-transporter IrtAB
Arnold FM, Weber MS, Gonda I, Gallenito MJ, Adenau S, Egloff P, Zimmermann I, Hutter CAJ, Hurlimann LM, Peters EE, Piel J, Meloni G, Medalia O, Seeger MA
Nature (2020) 580 pp. 413-417 [ Pubmed: 32296173 DOI: doi:10.1038/s41586-020-2136-9 ]