Cryo-electron microscopy structure of Plasmodium falciparum Rh5/CyRPA/Ripr invasion complex
Resolution: 7.17 Å
EM Method: Single-particle
Fitted PDBs: 6mpv
Q-score: 0.191
Wong W, Huang R, Menant S, Hong C, Sandow JJ, Birkinshaw RW, Healer J, Hodder AN, Kanjee U, Tonkin CJ, Heckmann D, Soroka V, Sogaard TMM, Jorgensen T, Duraisingh MT, Czabotar PE, de Jongh WA, Tham WH, Webb AI, Yu Z, Cowman AF
Nature (2019) 565 pp. 118-121 [ DOI: doi:10.1038/s41586-018-0779-6 Pubmed: 30542156 ]
- Pfrh5/cyrpa/pfripr complex (Complex from Plasmodium falciparum 3D7)
- Cysteine-rich protective antigen (39 kDa, Protein from Plasmodium falciparum (isolate 3D7))
- Pfripr (443 Da, Protein from Plasmodium falciparum 3D7)
- Pfripr (1 kDa, Protein from Plasmodium falciparum 3D7)
- Reticulocyte binding protein 5 (39 kDa, Protein from Plasmodium falciparum)
Resolution: 3.68 Å
EM Method: Single-particle
Fitted PDBs: 6d03
Q-score: 0.482
Gruszczyk J, Huang RK, Chan LJ, Menant S, Hong C, Murphy JM, Mok YF, Griffin MDW, Pearson RD, Wong W, Cowman AF, Yu Z, Tham WH
Nature (2018) 559 pp. 135-139 [ Pubmed: 29950717 DOI: doi:10.1038/s41586-018-0249-1 ]
- Ternary complex between human transferrin receptor 1, transferrin and plasmodium vivax reticulocyte-binding protein 2b (Complex from homo sapiens)
- Serotransferrin (77 kDa, Protein from Homo sapiens)
- Fe (iii) ion (55 Da, Ligand)
- Transferrin receptor protein 1 (73 kDa, Protein from Homo sapiens)
- Carbonate ion (60 Da, Ligand)
- Reticulocyte binding protein 2, putative (96 kDa, Protein from Plasmodium vivax)
- Calcium ion (40 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.74 Å
EM Method: Single-particle
Fitted PDBs: 6d04
Q-score: 0.444
Gruszczyk J, Huang RK, Chan LJ, Menant S, Hong C, Murphy JM, Mok YF, Griffin MDW, Pearson RD, Wong W, Cowman AF, Yu Z, Tham WH
Nature (2018) 559 pp. 135-139 [ Pubmed: 29950717 DOI: doi:10.1038/s41586-018-0249-1 ]
- Serotransferrin (77 kDa, Protein from Homo sapiens)
- Fe (iii) ion (55 Da, Ligand)
- Transferrin receptor protein 1 (73 kDa, Protein from Homo sapiens)
- Ternary complex between human transferrin receptor 1, transferrin and plasmodium vivax reticulocyte-binding protein 2b (Complex from Homo sapiens)
- Carbonate ion (60 Da, Ligand)
- Reticulocyte binding protein 2, putative (96 kDa, Protein from Plasmodium vivax)
- Calcium ion (40 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 6d05
Q-score: 0.419
Gruszczyk J, Huang RK, Chan LJ, Menant S, Hong C, Murphy JM, Mok YF, Griffin MDW, Pearson RD, Wong W, Cowman AF, Yu Z, Tham WH
Nature (2018) 559 pp. 135-139 [ Pubmed: 29950717 DOI: doi:10.1038/s41586-018-0249-1 ]
- Ternary complex between human transferrin receptor 1, transferrin and plasmodium vivax reticulocyte-binding protein 2b (Complex from homo sapiens)
- Serotransferrin (77 kDa, Protein from Homo sapiens)
- Fe (iii) ion (55 Da, Ligand)
- Transferrin receptor protein 1 (73 kDa, Protein from Homo sapiens)
- Carbonate ion (60 Da, Ligand)
- Reticulocyte binding protein 2, putative (96 kDa, Protein from Plasmodium vivax)
- Calcium ion (40 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)