Cryo-EM structure of the E. coli BrxX methyltransferase complexed with Ocr
Human calcium-sensing receptor bound with cinacalcet in detergent
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8wpg
Q-score: 0.541
Ling S, Meng X, Zhang Y, Xia Z, Zhou Y, Yang F, Shi P, Shi C, Tian C
Cell Res (2024) 34 pp. 169-172 [ DOI: doi:10.1038/s41422-023-00892-2 Pubmed: 37919470 ]
- Phosphate ion (94 Da, Ligand)
- N-[(1r)-1-(naphthalen-1-yl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine (357 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Tryptophan (204 Da, Ligand)
- Extracellular calcium-sensing receptor (102 kDa, Protein from Homo sapiens)
- Calcium sensing receptor dimer (Complex from Homo sapiens)
Human calcium-sensing receptor(CaSR) bound to cinacalcet in complex with Gq protein
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8wpu
Q-score: 0.49
Ling S, Meng X, Zhang Y, Xia Z, Zhou Y, Yang F, Shi P, Shi C, Tian C
Cell Res (2024) 34 pp. 169-172 [ DOI: doi:10.1038/s41422-023-00892-2 Pubmed: 37919470 ]
- Phosphate ion (94 Da, Ligand)
- N-[(1r)-1-(naphthalen-1-yl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine (357 Da, Ligand)
- Casr-gq complex (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Extracellular calcium-sensing receptor,calcium-sensing receptor (120 kDa, Protein from Homo sapiens)
- Tryptophan (204 Da, Ligand)
- G subunit q (gi2-mini-gq chimeric) (28 kDa, Protein from Homo sapiens)
- Scfv16 (31 kDa, Protein from Rattus norvegicus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
Structure of 1:1 PAPP-A.ProMBP complex(half map)
Resolution: 3.45 Å
EM Method: Single-particle
Fitted PDBs: 7y5n
Q-score: 0.476
Zhong Q, Chu H, Wang G, Zhang C, Li R, Guo F, Meng X, Lei X, Zhou Y, Ren R, Tao L, Li N, Gao N, Wei Y, Qiao J, Hang J
Cell Discov (2022) 8 pp. 137-137 [ Pubmed: 36550107 DOI: doi:10.1038/s41421-022-00502-2 ]
- Zinc ion (65 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Pappalysin-1 (172 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Structure of 1:1 papp-a/prombp complex(half map) (Complex from Homo sapiens)
- Bone marrow proteoglycan (25 kDa, Protein from Homo sapiens)
Structure of 1:1 PAPP-A.STC2 complex(half map)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7y5q
Q-score: 0.438
Zhong Q, Chu H, Wang G, Zhang C, Li R, Guo F, Meng X, Lei X, Zhou Y, Ren R, Tao L, Li N, Gao N, Wei Y, Qiao J, Hang J
Cell Discov (2022) 8 pp. 137-137 [ Pubmed: 36550107 DOI: doi:10.1038/s41421-022-00502-2 ]
- Maltose/maltodextrin-binding periplasmic protein,pappalysin-1 (216 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Structure of 1:1 papp-a/stc2 complex(half map) (Complex from Homo sapiens)
- Stanniocalcin-2 (33 kDa, Protein from Homo sapiens)
Structure of 2:2 PAPP-A.ProMBP comple
Resolution: 3.64 Å
EM Method: Single-particle
Fitted PDBs: 8hgg
Q-score: 0.408
Zhong Q, Chu H, Wang G, Zhang C, Li R, Guo F, Meng X, Lei X, Zhou Y, Ren R, Tao L, Li N, Gao N, Wei Y, Qiao J, Hang J
Cell Discov (2022) 8 pp. 137-137 [ Pubmed: 36550107 DOI: doi:10.1038/s41421-022-00502-2 ]
- Bone marrow proteoglycan (25 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Structure of 2:2 papp-a/prombp complex (Complex from Homo sapiens)
- Pappalysin-1 (181 kDa, Protein from Homo sapiens)
Structure of 2:2 PAPP-A.STC2 complex
Resolution: 4.16 Å
EM Method: Single-particle
Fitted PDBs: 8hgh
Q-score: 0.295
Zhong Q, Chu H, Wang G, Zhang C, Li R, Guo F, Meng X, Lei X, Zhou Y, Ren R, Tao L, Li N, Gao N, Wei Y, Qiao J, Hang J
Cell Discov (2022) 8 pp. 137-137 [ Pubmed: 36550107 DOI: doi:10.1038/s41421-022-00502-2 ]
- Structure of 2:2 papp-a/stc2 complex (Complex from Homo sapiens)
- Maltose/maltodextrin-binding periplasmic protein,pappalysin-1 (216 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Stanniocalcin-2 (33 kDa, Protein from Homo sapiens)