Cryo-EM structure of AAV-2 in complex with AAVR PKD domains 1 and 2
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 6nz0
Q-score: 0.665
Meyer NL, Hu G, Davulcu O, Xie Q, Noble AJ, Yoshioka C, Gingerich DS, Trzynka A, David L, Stagg SM, Chapman MS
eLife (2019) 8 [ DOI: doi:10.7554/eLife.44707 Pubmed: 31115336 ]
- Binary complex of aav-2 with a fragment of its cellular receptor, aavr or dyslexia-associated protein kiaa0319-like protein. (Complex from Homo sapiens)
- Adeno-associated virus - 2 (22 kDa, Virus from Adeno-associated virus - 2)
- Capsid protein vp1 (82 kDa, Protein from Adeno-associated virus - 2)
- Magnesium ion (24 Da, Ligand)
- Dyslexia-associated protein kiaa0319-like protein (31 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
Structure of the AAV2 with its Cell Receptor, AAVR
Meyer NL, Hu G, Davulcu O, Xie Q, Noble AJ, Yoshioka C, Gingerich DS, Trzynka A, David L, Stagg SM, Chapman MS
eLife (2019) 8 [ DOI: doi:10.7554/eLife.44707 Pubmed: 31115336 ]
- Aav2 complex with aavr receptor (3 MDa, Complex from Adeno-associated virus)
Structure of the AAV2 with its Cell Receptor, AAVR
Meyer NL, Hu G, Davulcu O, Xie Q, Noble AJ, Yoshioka C, Gingerich DS, Trzynka A, David L, Stagg SM, Chapman MS
eLife (2019) 8 [ DOI: doi:10.7554/eLife.44707 Pubmed: 31115336 ]
- Aav2 complex with aavr receptor (3 MDa, Complex from Adeno-associated virus)
Structure of the AAV2 with its Cell Receptor, AAVR
Meyer NL, Hu G, Davulcu O, Xie Q, Noble AJ, Yoshioka C, Gingerich DS, Trzynka A, David L, Stagg SM, Chapman MS
eLife (2019) 8 [ DOI: doi:10.7554/eLife.44707 Pubmed: 31115336 ]
- Aav2 complex with aavr receptor (3 MDa, Complex from Adeno-associated virus)
Structure of the AAV2 with its Cell Receptor, AAVR
Meyer NL, Hu G, Davulcu O, Xie Q, Noble AJ, Yoshioka C, Gingerich DS, Trzynka A, David L, Stagg SM, Chapman MS
eLife (2019) 8 [ DOI: doi:10.7554/eLife.44707 Pubmed: 31115336 ]
- Aav2 complex with aavr receptor (3 MDa, Complex from Adeno-associated virus)
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 5uf6
Q-score: 0.591
Xie Q, Spear JM, Noble AJ, Sousa DR, Meyer NL, Davulcu O, Zhang F, Linhardt RJ, Stagg SM, Chapman MS
Mol Ther Methods Clin Dev (2017) 5 pp. 1-12 [ Pubmed: 28480299 DOI: doi:10.1016/j.omtm.2017.02.004 ]
- Adeno-associated virus (3 MDa, Virus from Adeno-associated virus)
Resolution: 4.8 Å
EM Method: Single-particle
Fitted PDBs: 3j4p
Q-score: 0.332
Xie Q, Spilman M, Meyer NL, Lerch TF, Stagg SM, Chapman MS
J Struct Biol (2013) 184 pp. 129-135 [ DOI: doi:10.1016/j.jsb.2013.09.004 Pubmed: 24036405 ]
Structure of AAV-DJ, a Retargeted Gene Therapy Vector: Cryo-Electron Microscopy at 4.5A resolution
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 3j1q
Q-score: 0.259
Lerch TF, O'Donnell JK, Meyer NL, Xie Q, Taylor KA, Stagg SM, Chapman MS
Structure (2012) 20 pp. 1310-1320 [ DOI: doi:10.1016/j.str.2012.05.004 Pubmed: 22727812 ]
- Adeno-associated virus (3 MDa, Virus from Adeno-associated virus)
- Aav-dj (3 MDa, Sample)