TMEM106B filaments with Fold I-d from Multiple system atrophy (case 18)
Resolution: 3.64 Å
EM Method: Helical reconstruction
Fitted PDBs: 7qvf
Q-score: 0.469
Schweighauser M, Arseni D, Bacioglu M, Huang M, Lovestam S, Shi Y, Yang Y, Zhang W, Kotecha A, Garringer HJ, Vidal R, Hallinan GI, Newell KL, Tarutani A, Murayama S, Miyazaki M, Saito Y, Yoshida M, Hasegawa K, Lashley T, Revesz T, Kovacs GG, van Swieten J, Takao M, Hasegawa M, Ghetti B, Spillantini MG, Ryskeldi-Falcon B, Murzin AG, Goedert M, Scheres SHW
Nature (2022) 605 pp. 310-314 [ DOI: doi:10.1038/s41586-022-04650-z Pubmed: 35344985 ]
- Transmembrane protein 106b (31 kDa, Protein from Homo sapiens)
- Tmem106b (Tissue from Homo sapiens)
TMEM106B filaments with Fold IIa from Multiple system atrophy (case 19)
Resolution: 3.38 Å
EM Method: Helical reconstruction
Fitted PDBs: 7qwg
Q-score: 0.53
Schweighauser M, Arseni D, Bacioglu M, Huang M, Lovestam S, Shi Y, Yang Y, Zhang W, Kotecha A, Garringer HJ, Vidal R, Hallinan GI, Newell KL, Tarutani A, Murayama S, Miyazaki M, Saito Y, Yoshida M, Hasegawa K, Lashley T, Revesz T, Kovacs GG, van Swieten J, Takao M, Hasegawa M, Ghetti B, Spillantini MG, Ryskeldi-Falcon B, Murzin AG, Goedert M, Scheres SHW
Nature (2022) 605 pp. 310-314 [ DOI: doi:10.1038/s41586-022-04650-z Pubmed: 35344985 ]
- Transmembrane protein 106b (31 kDa, Protein from Homo sapiens)
- Tmem106b (Tissue from Homo sapiens)
TMEM106B filaments with Fold IIb from Multiple system atrophy (case 19)
Resolution: 3.47 Å
EM Method: Helical reconstruction
Fitted PDBs: 7qwl
Q-score: 0.513
Schweighauser M, Arseni D, Bacioglu M, Huang M, Lovestam S, Shi Y, Yang Y, Zhang W, Kotecha A, Garringer HJ, Vidal R, Hallinan GI, Newell KL, Tarutani A, Murayama S, Miyazaki M, Saito Y, Yoshida M, Hasegawa K, Lashley T, Revesz T, Kovacs GG, van Swieten J, Takao M, Hasegawa M, Ghetti B, Spillantini MG, Ryskeldi-Falcon B, Murzin AG, Goedert M, Scheres SHW
Nature (2022) 605 pp. 310-314 [ DOI: doi:10.1038/s41586-022-04650-z Pubmed: 35344985 ]
- Transmembrane protein 106b (31 kDa, Protein from Homo sapiens)
- Tmem106b (Tissue from Homo sapiens)
Globular glial tauopathy type 1 tau filament
Resolution: 3.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 7p66
Q-score: 0.546
Shi Y, Zhang W, Yang Y, Murzin AG, Falcon B, Kotecha A, van Beers M, Tarutani A, Kametani F, Garringer HJ, Vidal R, Hallinan GI, Lashley T, Saito Y, Murayama S, Yoshida M, Tanaka H, Kakita A, Ikeuchi T, Robinson AC, Mann DMA, Kovacs GG, Revesz T, Ghetti B, Hasegawa M, Goedert M, Scheres SHW
Nature (2021) 598 pp. 359-363 [ DOI: doi:10.1038/s41586-021-03911-7 Pubmed: 34588692 ]
Globular glial tauopathy type 2 tau filament
Resolution: 3.1 Å
EM Method: Helical reconstruction
Fitted PDBs: 7p67
Q-score: 0.566
Shi Y, Zhang W, Yang Y, Murzin AG, Falcon B, Kotecha A, van Beers M, Tarutani A, Kametani F, Garringer HJ, Vidal R, Hallinan GI, Lashley T, Saito Y, Murayama S, Yoshida M, Tanaka H, Kakita A, Ikeuchi T, Robinson AC, Mann DMA, Kovacs GG, Revesz T, Ghetti B, Hasegawa M, Goedert M, Scheres SHW
Nature (2021) 598 pp. 359-363 [ DOI: doi:10.1038/s41586-021-03911-7 Pubmed: 34588692 ]
Argyrophilic grain disease type 1 tau filament
Resolution: 3.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 7p6d
Q-score: 0.518
Shi Y, Zhang W, Yang Y, Murzin AG, Falcon B, Kotecha A, van Beers M, Tarutani A, Kametani F, Garringer HJ, Vidal R, Hallinan GI, Lashley T, Saito Y, Murayama S, Yoshida M, Tanaka H, Kakita A, Ikeuchi T, Robinson AC, Mann DMA, Kovacs GG, Revesz T, Ghetti B, Hasegawa M, Goedert M, Scheres SHW
Nature (2021) 598 pp. 359-363 [ DOI: doi:10.1038/s41586-021-03911-7 Pubmed: 34588692 ]
Argyrophilic grain disease type 2 tau filament
Resolution: 3.4 Å
EM Method: Helical reconstruction
Fitted PDBs: 7p6e
Q-score: 0.488
Shi Y, Zhang W, Yang Y, Murzin AG, Falcon B, Kotecha A, van Beers M, Tarutani A, Kametani F, Garringer HJ, Vidal R, Hallinan GI, Lashley T, Saito Y, Murayama S, Yoshida M, Tanaka H, Kakita A, Ikeuchi T, Robinson AC, Mann DMA, Kovacs GG, Revesz T, Ghetti B, Hasegawa M, Goedert M, Scheres SHW
Nature (2021) 598 pp. 359-363 [ DOI: doi:10.1038/s41586-021-03911-7 Pubmed: 34588692 ]