Cryo-EM structure of Streptococcus pneumoniae NADPH oxidase
Resolution: 2.29 Å
EM Method: Single-particle
Fitted PDBs: 8qt6
Q-score: 0.678
Dubach VRA, San Segundo-Acosta P, Murphy BJ
Nat Struct Mol Biol (2024) 31 pp. 1769-1777 [ Pubmed: 39039317 DOI: doi:10.1038/s41594-024-01348-w ]
- Water (18 Da, Ligand)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Fad-binding fr-type domain-containing protein (46 kDa, Protein from Streptococcus pneumoniae)
- Streptococcus pneumoniae nadph oxidase with fad and heme cofactors (46 kDa, Complex from Streptococcus pneumoniae)
- Streptococcus pneumoniae nadph oxidase (Complex from Streptococcus pneumoniae)
- Flavin-adenine dinucleotide (785 Da, Ligand)
Cryo-EM structure of Streptococcus pneumoniae NADPH oxidase in complex with NADPH
Resolution: 2.2 Å
EM Method: Single-particle
Fitted PDBs: 8qt7
Q-score: 0.691
Dubach VRA, San Segundo-Acosta P, Murphy BJ
Nat Struct Mol Biol (2024) 31 pp. 1769-1777 [ Pubmed: 39039317 DOI: doi:10.1038/s41594-024-01348-w ]
- Water (18 Da, Ligand)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Fad-binding fr-type domain-containing protein (46 kDa, Protein from Streptococcus pneumoniae)
- Streptococcus pneumoniae nadph oxidase with fad and heme cofactors (46 kDa, Complex from Streptococcus pneumoniae)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Flavin-adenine dinucleotide (785 Da, Ligand)
Cryo-EM structure of stably reduced Streptococcus pneumoniae NADPH oxidase in complex with NADH
Resolution: 2.36 Å
EM Method: Single-particle
Fitted PDBs: 8qt9
Q-score: 0.675
Dubach VRA, San Segundo-Acosta P, Murphy BJ
Nat Struct Mol Biol (2024) 31 pp. 1769-1777 [ Pubmed: 39039317 DOI: doi:10.1038/s41594-024-01348-w ]
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Streptococcus pneumoniae nadph oxidase with fad and heme cofactors and nadh bound (Complex from Streptococcus pneumoniae)
- Water (18 Da, Ligand)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Fad-binding fr-type domain-containing protein (46 kDa, Protein from Streptococcus pneumoniae)
- Flavin-adenine dinucleotide (785 Da, Ligand)
Cryo-EM structure of Streptococcus pneumoniae NADPH oxidase F397A mutant in complex with NADPH
Resolution: 2.64 Å
EM Method: Single-particle
Fitted PDBs: 8qta
Q-score: 0.621
Dubach VRA, San Segundo-Acosta P, Murphy BJ
Nat Struct Mol Biol (2024) 31 pp. 1769-1777 [ Pubmed: 39039317 DOI: doi:10.1038/s41594-024-01348-w ]
- Water (18 Da, Ligand)
- Fad-binding fr-type domain-containing protein (45 kDa, Protein from Streptococcus pneumoniae)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Protein-substrate complex of nadph oxidase with nadph (46 kDa, Complex from Streptococcus pneumoniae)
- Flavin-adenine dinucleotide (785 Da, Ligand)