EMDB < Search results

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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primary_citation_author:"Murshudov GN"

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EMD-13097

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human DEPTOR in a complex with mutant human mTORC1 A1459P

Release date: Sept. 8, 2021
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 7owg
Q-score: 0.293

Heimhalt M, Berndt A, Wagstaff J, Anandapadamanaban M, Perisic O, Maslen S, McLaughlin S, Yu CW, Masson GR, Boland A, Ni X, Yamashita K, Murshudov GN, Skehel M, Freund SM, Williams RL

eLife (2021) 10 [ Pubmed: 34519269 DOI: doi:10.7554/eLife.68799 ]

Sample:

Complex of human mutant mtorc1 a1459p with the inhibitory protein deptor (46 MDa, Complex)
Regulatory-associated protein of mtor (149 kDa, Protein from Homo sapiens)
Dep domain-containing mtor-interacting protein (46 kDa, Protein from Homo sapiens)
Target of rapamycin complex subunit lst8 (35 kDa, Protein from Homo sapiens)
Deptor (Complex from Homo sapiens)
Mtorc1 with mutant a1459p mtor (Complex from Homo sapiens)
Serine/threonine-protein kinase mtor (287 kDa, Protein from Homo sapiens)

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EMD-2848

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actin-like ParM protein bound to ADP

Release date: May 6, 2015
Resolution: 11.0 Å
EM Method: Helical reconstruction

Bharat TAM, Murshudov GN, Sachse C, Lowe J

Nature (2015) 523 pp. 106-110 [ Pubmed: 25915019 DOI: doi:10.1038/nature14356 ]

Sample:

Parm bound to adp (Sample)
Parm (36 kDa, Protein from Escherichia coli)

EMD-2849

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E coli cell with plasmid containing the ParMRC locus

Release date: May 6, 2015
EM Method: Tomography

Bharat TAM, Murshudov GN, Sachse C, Lowe J

Nature (2015) 523 pp. 106-110 [ Pubmed: 25915019 DOI: doi:10.1038/nature14356 ]

Sample:

EMD-2850

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actin-like ParM protein bound to AMPPNP

Release date: April 22, 2015
Resolution: 4.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 5aey
Q-score: 0.398

Bharat TAM, Murshudov GN, Sachse C, Lowe J

Nature (2015) 523 pp. 106-110 [ Pubmed: 25915019 DOI: doi:10.1038/nature14356 ]

Sample:

Parm bound to amppnp (Sample)
Parm (36 kDa, Protein from Escherichia coli)

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