Resolution: 3.13 Å
EM Method: Single-particle
Fitted PDBs: 8bdz
Q-score: 0.505
Egorov VV, Shvetsov AV, Pichkur EB, Shaldzhyan AA, Zabrodskaya YA, Vinogradova DS, Nekrasov PA, Gorshkov AN, Garmay YP, Kovaleva AA, Stepanova LA, Tsybalova LM, Shtam TA, Myasnikov AG, Konevega AL
Biophys.Chem. (2022) 293 pp. 106943-106943 [ Pubmed: 36495688 DOI: doi:10.1016/j.bpc.2022.106943 ]
- Hepatitis b virus core antigen (hbc) with the insertion of four external domains of the influenza a m2 protein (t=4) (30 MDa, Complex from Hepatitis B virus)
- Core protein,matrix protein 2,external core antigen (30 kDa, Protein from Hepatitis B virus genotype D subtype ayw (isolate France/Tiollais/1979))
Atomic cryoEM structure of Hsp90-Hsp70-Hop-GR
Resolution: 3.57 Å
EM Method: Single-particle
Fitted PDBs: 7kw7
Q-score: 0.276
Wang RY, Noddings CM, Kirschke E, Myasnikov AG, Johnson JL, Agard DA
Nature (2022) 601 pp. 460-464 [ DOI: doi:10.1038/s41586-021-04252-1 Pubmed: 34937942 ]
- Magnesium ion (24 Da, Ligand)
- Heat shock 70 kda protein 1a (Complex from Homo sapiens)
- Hsp90-hsp70-hop-gr complex (Complex)
- Heat shock protein hsp 90-alpha (Complex from Homo sapiens)
- Potassium ion (39 Da, Ligand)
- Heat shock protein hsp 90-alpha (84 kDa, Protein from Homo sapiens)
- Stress-induced-phosphoprotein 1 (62 kDa, Protein from Homo sapiens)
- Glucocorticoid receptor (Complex from Homo sapiens)
- Heat shock 70 kda protein 1a (70 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Stress-induced-phosphoprotein 1 (Complex from Homo sapiens)
- Glucocorticoid receptor (85 kDa, Protein from Homo sapiens)
Full-length human mitochondrial Hsp90 (TRAP1) with AMP-PNP
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 7kck
Q-score: 0.477
Liu YX, Agard DA, Elnatan D, Sun M, Myasnikov AG
To Be Published
- Magnesium ion (24 Da, Ligand)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Human trap1 dimer with amp-pnp (147 kDa, Complex from Homo sapiens)
- Potassium ion (39 Da, Ligand)
- Heat shock protein 75 kda, mitochondrial (74 kDa, Protein from Homo sapiens)
Full-length human mitochondrial Hsp90 (TRAP1) in complex with SdhB in the presence of AMP-PNP
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 7kcl
Q-score: 0.506
Liu YX, Agard DA, Elnatan D, Sun M, Myasnikov AG
To Be Published
- Magnesium ion (24 Da, Ligand)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (15 kDa, Protein from Homo sapiens)
- Human trap1 in complex with sdhb in the presence of amp-pnp (162 kDa, Complex from Homo sapiens)
- Heat shock protein 75 kda, mitochondrial (74 kDa, Protein from Homo sapiens)
Liu YX, Agard DA, Elnatan D, Sun M, Myasnikov AG
To Be Published
- Sdhb (Protein from Homo sapiens)
- Trap1 (Protein from Homo sapiens)
- Human trap1 in complex with sdhb in the presence of amp-pnp (162 kDa, Complex from Homo sapiens)
Human TRAP1 binding with SdhB folding intermediate state in the presence of AMP-PNP
Liu YX, Agard DA, Elnatan D, Sun M, Myasnikov AG
To Be Published
- Sdhb (Protein from Homo sapiens)
- Trap1 (Protein from Homo sapiens)
- Human trap1 in complex with sdhb in the presence of amp-pnp (162 kDa, Complex from Homo sapiens)
Full-length human mitochondrial Hsp90 (TRAP1) in complex with SdhB in the presence of AMP-PNP
Resolution: 3.43 Å
EM Method: Single-particle
Fitted PDBs: 7kcm
Q-score: 0.459
Liu YX, Agard DA, Elnatan D, Sun M, Myasnikov AG
To Be Published
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (15 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Human trap1 in complex with sdhb in the presence of amp-pnp (162 kDa, Complex from Homo sapiens)
- Heat shock protein 75 kda, mitochondrial (74 kDa, Protein from Homo sapiens)
30S ribosomal subunit from E. coli
Resolution: 3.05 Å
EM Method: Single-particle
Fitted PDBs: 7oe1
Q-score: 0.373
Maksimova EM, Korepanov AP, Kravchenko OV, Baymukhametov TN, Myasnikov AG, Vassilenko KS, Afonina ZA, Stolboushkina EA
Int J Mol Sci (2021) 22 [ Pubmed: 34200244 DOI: doi:10.3390/ijms22116140 ]
- 30s ribosomal protein s15 (10 kDa, Protein from Escherichia coli str. K-12 substr. MG1655)
- 30s ribosomal protein s13 (12 kDa, Protein from Escherichia coli str. K-12 substr. MG1655)
- 16s rrna (499 kDa, RNA from Escherichia coli str. K-12 substr. MG1655)
- 30s ribosomal protein s9 (14 kDa, Protein from Escherichia coli str. K-12 substr. MG1655)
- 30s ribosomal protein s19 (10 kDa, Protein from Escherichia coli str. K-12 substr. MG1655)
- 30s ribosomal subunit from e.coli (850 kDa, Complex from Escherichia coli str. K-12 substr. MG1655)
- 30s ribosomal protein s14 (11 kDa, Protein from Escherichia coli str. K-12 substr. MG1655)
- 30s ribosomal protein s7 (19 kDa, Protein from Escherichia coli str. K-12 substr. MG1655)
- 30s ribosomal protein s6, fully modified isoform (15 kDa, Protein from Escherichia coli str. K-12 substr. MG1655)
- 30s ribosomal protein s12 (13 kDa, Protein from Escherichia coli str. K-12 substr. MG1655)
- 30s ribosomal protein s2 (26 kDa, Protein from Escherichia coli str. K-12 substr. MG1655)
- 30s ribosomal protein s18 (8 kDa, Protein from Escherichia coli str. K-12 substr. MG1655)
- 30s ribosomal protein s3 (25 kDa, Protein from Escherichia coli str. K-12 substr. MG1655)
- 30s ribosomal protein s20 (9 kDa, Protein from Escherichia coli str. K-12 substr. MG1655)
- 30s ribosomal protein s17 (9 kDa, Protein from Escherichia coli str. K-12 substr. MG1655)
- 30s ribosomal protein s4 (23 kDa, Protein from Escherichia coli str. K-12 substr. MG1655)
- 30s ribosomal protein s10 (11 kDa, Protein from Escherichia coli str. K-12 substr. MG1655)
- 30s ribosomal protein s11 (13 kDa, Protein from Escherichia coli (strain K12))
- 30s ribosomal protein s21 (8 kDa, Protein from Escherichia coli str. K-12 substr. MG1655)
- 30s ribosomal protein s5 (17 kDa, Protein from Escherichia coli str. K-12 substr. MG1655)
- 30s ribosomal protein s16 (9 kDa, Protein from Escherichia coli str. K-12 substr. MG1655)
- 30s ribosomal protein s8 (14 kDa, Protein from Escherichia coli str. K-12 substr. MG1655)
Apo full-length Hsc82 in complex with Aha1
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 6xlb
Q-score: 0.343
Liu YX, Sun M, Myasnikov AG, Elnatan D, Agard DA
To Be Published
- Hsc82 in complex with aha1 ctd (Complex from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Hsp90 co-chaperone aha1 (39 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Atp-dependent molecular chaperone hsc82 (81 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))