CryoEM structure of Western equine encephalitis virus VLP in complex with the avian MXRA8 receptor
Resolution: 4.74 Å
EM Method: Single-particle
Fitted PDBs: 8dan
Q-score: 0.248
Zimmerman O, Zimmerman MI, Nelson CA, Raju S, Errico JM, Madden EA, Hassan AO, VanBlargan LA, Kim AS, Adams LJ, Basore K, Whitener BM, Earnest JT, Holmes AC, Ebel GD, Zmasek C, Scheuermann RH, Fremont DH, Diamond MS
To Be Published
- E1 envelope glycoprotein (47 kDa, Protein from Western equine encephalitis virus)
- Western equine encephalitis virus vlp in complex with avian mxra8 receptor (495 MDa, Complex from Western equine encephalitis virus)
- Matrix remodeling-associated protein 8 (30 kDa, Protein from Asarcornis scutulata)
- E2 envelope glycoprotein (46 kDa, Protein from Western equine encephalitis virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
CryoEM structure of Western equine encephalitis virus VLP
Resolution: 4.35 Å
EM Method: Single-particle
Fitted PDBs: 8daq
Q-score: 0.3
Zimmerman O, Zimmerman MI, Nelson CA, Raju S, Errico JM, Madden EA, Hassan AO, VanBlargan LA, Kim AS, Adams LJ, Basore K, Whitener BM, Earnest JT, Holmes AC, Ebel GD, Zmasek C, Scheuermann RH, Fremont DH, Diamond MS
To Be Published
- Western equine encephalitis virus (Virus from Western equine encephalitis virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- E1 envelope glycoprotein (47 kDa, Protein from Western equine encephalitis virus)
- E2 envelope glycoprotein (46 kDa, Protein from Western equine encephalitis virus)
Resolution: 3.89 Å
EM Method: Single-particle
Fitted PDBs: 8sqn
Q-score: 0.366
Zimmerman O, Zimmerman MI, Raju S, Nelson CA, Errico JM, Madden EA, Holmes AC, Hassan AO, VanBlargan LA, Kim AS, Adams LJ, Basore K, Whitener BM, Palakurty S, Davis-Adams HG, Sun C, Gilliland Jr T, Earnest JT, Ma H, Ebel GD, Zmasek C, Scheuermann RH, Klimstra WB, Fremont DH, Diamond MS
Cell (2023) 186 pp. 4818-4833.e25 [ Pubmed: 37804831 DOI: doi:10.1016/j.cell.2023.09.007 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- E1 envelope glycoprotein (47 kDa, Protein from Western equine encephalitis virus)
- E2 envelope glycoprotein (46 kDa, Protein from Western equine encephalitis virus)
- Western equine encephalitis virus vlp in complex with a chimeric mxra8 receptor (avian d1 with mammalian d2) (7 MDa, Complex from Western equine encephalitis virus)
- Dud1mod2 chimeric mxra8 (30 kDa, Protein from Anas platyrhynchos)
CryoEM structure of Western equine encephalitis virus VLP in complex with the avian MXRA8 receptor
Resolution: 3.92 Å
EM Method: Single-particle
Fitted PDBs: 8ewf
Q-score: 0.321
Zimmerman O, Zimmerman MI, Nelson CA, Raju S, Errico JM, Madden EA, Hassan AO, VanBlargan LA, Kim AS, Adams LJ, Basore K, Whitener BM, Earnest JT, Holmes AC, Ebel GD, Zmasek C, Scheuermann RH, Fremont DH, Diamond MS
To Be Published
- Chikungunya virus vlp in complex with a chimeric mxra8 receptor (avian d1 with mammalian d2) (495 MDa, Complex from Chikungunya virus)
- Chimeric mxra8 receptor: d1 from duck mxra8 and d2 from mouse mxra8 (30 kDa, Protein from Anas platyrhynchos)
- Spike glycoprotein e2 (46 kDa, Protein from Chikungunya virus)
- E1 envelope protein (47 kDa, Protein from Chikungunya virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Basore K, Ma H, Kafai NM, Mackin S, Kim AS, Nelson CA, Diamond MS, Fremont DH
Nature (2021) 598 pp. 672-676 [ Pubmed: 34646020 DOI: doi:10.1038/s41586-021-03963-9 ]
- E1 envelope glycoprotein (Protein from Venezuelan equine encephalitis virus)
- Venezuelan equine encephalitis vlp in complex with domains 1 and 2 of the ldlrad3 receptor (Complex from Mus musculus)
- Venezuelan equine encephalitis vlp (Complex from Venezuelan equine encephalitis virus)
- E2 envelope glycoprotein (Protein from Venezuelan equine encephalitis virus)
- Ldlrad3 receptor domains 1 and 2 (Cellular component from Mus musculus)
- Low-density lipoprotein receptor class a domain-containing protein 3 (Protein from Mus musculus)
- Capsid (Protein from Venezuelan equine encephalitis virus)
CryoEM structure of Venezuelan equine encephalitis virus VLP in complex with the LDLRAD3 receptor
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 7n1h
Q-score: 0.149
Basore K, Ma H, Kafai NM, Mackin S, Kim AS, Nelson CA, Diamond MS, Fremont DH
Nature (2021) 598 pp. 672-676 [ Pubmed: 34646020 DOI: doi:10.1038/s41586-021-03963-9 ]
- Calcium ion (40 Da, Ligand)
- E2 envelope glycoprotein (47 kDa, Protein from Venezuelan equine encephalitis virus)
- Venezuelan equine encephalitis vlp (Complex from Venezuelan equine encephalitis virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Capsid (18 kDa, Protein from Venezuelan equine encephalitis virus)
- Venezuelan equine encephalitis vlp in complex with domain 1 of the ldlrad3 receptor (Complex from Venezuelan equine encephalitis virus)
- E1 envelope glycoprotein (47 kDa, Protein from Venezuelan equine encephalitis virus)
- Low-density lipoprotein receptor class a domain-containing protein 3 (4 kDa, Protein from Mus musculus)
- Ldlrad3 receptor domain 1 (Cellular component from Mus musculus)
CryoEM structure of Venezuelan equine encephalitis virus VLP
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 7n1i
Q-score: 0.144
Basore K, Ma H, Kafai NM, Mackin S, Kim AS, Nelson CA, Diamond MS, Fremont DH
Nature (2021) 598 pp. 672-676 [ Pubmed: 34646020 DOI: doi:10.1038/s41586-021-03963-9 ]
- E2 envelope glycoprotein (47 kDa, Protein from Venezuelan equine encephalitis virus)
- E1 envelope glycoprotein (47 kDa, Protein from Venezuelan equine encephalitis virus)
- Capsid (18 kDa, Protein from Venezuelan equine encephalitis virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Venezuelan equine encephalitis virus (Virus from Venezuelan equine encephalitis virus)
Electron Cryo-Microscopy Of Chikungunya VLP
Resolution: 4.16 Å
EM Method: Single-particle
Fitted PDBs: 6nk5
Q-score: 0.304
Basore K, Kim AS, Nelson CA, Zhang R, Smith BK, Uranga C, Vang L, Cheng M, Gross ML, Smith J, Diamond MS, Fremont DH
Cell (2019) 177 pp. 1725- [ Pubmed: 31080061 DOI: doi:10.1016/j.cell.2019.04.006 ]
- E2 glycoprotein (46 kDa, Protein from Chikungunya virus (strain 37997))
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Chikungunya virus (Virus from Chikungunya virus)
- Capsid protein (16 kDa, Protein from Chikungunya virus (strain 37997))
- E1 glycoprotein (47 kDa, Protein from Chikungunya virus (strain 37997))
Electron Cryo-Microscopy Of Chikungunya VLP in complex with mouse Mxra8 receptor
Resolution: 4.06 Å
EM Method: Single-particle
Fitted PDBs: 6nk6
Q-score: 0.266
Basore K, Kim AS, Nelson CA, Zhang R, Smith BK, Uranga C, Vang L, Cheng M, Gross ML, Smith J, Diamond MS, Fremont DH
Cell (2019) 177 pp. 1725- [ Pubmed: 31080061 DOI: doi:10.1016/j.cell.2019.04.006 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Capsid protein (16 kDa, Protein from Chikungunya virus strain Senegal 37997)
- Chikungunya virus like particle with mxra8 (Complex)
- E1 glycoprotein (47 kDa, Protein from Chikungunya virus strain Senegal 37997)
- E2 glycoprotein (46 kDa, Protein from Chikungunya virus strain Senegal 37997)
- Matrix remodeling-associated protein 8 (30 kDa, Protein from Mus musculus)
- Chikungunya virus like particle (Complex from Chikungunya virus (strain 37997))
- Mxra8 receptor (Complex from Mus musculus)
Electron Cryo-Microscopy of Chikungunya in Complex with Mouse Mxra8 Receptor
Resolution: 4.99 Å
EM Method: Single-particle
Fitted PDBs: 6nk7
Q-score: 0.205
Basore K, Kim AS, Nelson CA, Zhang R, Smith BK, Uranga C, Vang L, Cheng M, Gross ML, Smith J, Diamond MS, Fremont DH
Cell (2019) 177 pp. 1725- [ DOI: doi:10.1016/j.cell.2019.04.006 Pubmed: 31080061 ]
- Matrix remodeling-associated protein 8 (30 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- E1 glycoprotein (47 kDa, Protein from Chikungunya virus)
- Capsid protein (16 kDa, Protein from Chikungunya virus)
- Chikungunya virus with mxra8 receptor (Complex)
- E2 glycoprotein (47 kDa, Protein from Chikungunya virus)
- Mouse mxra8 receptor ectodomain (Complex from Mus musculus)
- Chikungunya virus (Complex from Chikungunya virus)
- E3 glycoprotein (6 kDa, Protein from Chikungunya virus)