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EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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primary_citation_author:"Niu F"

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EMD-38989

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Cryo-EM structure of full-length MICAL1 in the autoinhibited state

Release date: Aug. 28, 2024
Resolution: 3.94 Å
EM Method: Single-particle
Fitted PDBs: 8y6k
Q-score: 0.183

Lin L, Dong J, Xu S, Xiao J, Yu C, Niu F, Wei Z

Nat Commun (2024) 15 pp. 6824-6824 [ DOI: doi:10.1038/s41467-024-50940-7 Pubmed: 39122694 ]

Sample:

Flavin-adenine dinucleotide (785 Da, Ligand)
Zinc ion (65 Da, Ligand)
[f-actin]-monooxygenase mical1 (118 kDa, Protein from Homo sapiens)
Full-length mical1 protein (106 kDa, Complex from Homo sapiens)

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EMD-37260

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Cryo-EM structure of Myosin VI in the autoinhibited state (without SAH-extension density)

Release date: Feb. 21, 2024
Resolution: 3.54 Å
EM Method: Single-particle
Fitted PDBs: 8w41
Q-score: 0.34

Niu F, Li L, Wang L, Xiao J, Xu S, Liu Y, Lin L, Yu C, Wei Z

Nat Commun (2024) 15 pp. 1187-1187 [ DOI: doi:10.1038/s41467-024-45424-7 Pubmed: 38331992 ]

Sample:

Complex of myosin vi and calmodulin (Complex)
Unconventional myosin-vi (148 kDa, Protein from Homo sapiens)
Phosphate ion (94 Da, Ligand)
Magnesium ion (24 Da, Ligand)
Calmodulin-1 (16 kDa, Protein from Mus musculus)
Adenosine-5'-diphosphate (427 Da, Ligand)
Myosin vi (Complex from Homo sapiens)
Calmodulin (Complex from Mus musculus)
Calcium ion (40 Da, Ligand)

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EMD-37261

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Cryo-EM map of Myosin VI in the autoinhibited state (with SAH-extension density)

Release date: Feb. 21, 2024
Resolution: 4.14 Å
EM Method: Single-particle

Niu F, Li L, Wang L, Xiao J, Xu S, Liu Y, Lin L, Yu C, Wei Z

Nat Commun (2024) 15 pp. 1187-1187 [ DOI: doi:10.1038/s41467-024-45424-7 Pubmed: 38331992 ]

Sample:

Complex of myosin vi and calmodulin (Complex)
Calmodulin (Protein from Mus musculus)
Calmodulin (Complex from Mus musculus)
Myosin vi (Protein from Homo sapiens)
Myosin vi (Complex from Homo sapiens)

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EMD-34121

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Cryo-EM structure of full-length Myosin Va in the autoinhibited state

Release date: Dec. 21, 2022
Resolution: 4.78 Å
EM Method: Single-particle
Fitted PDBs: 7yv9
Q-score: 0.189

Niu F, Liu Y, Sun K, Xu S, Dong J, Yu C, Yan K, Wei Z

Sci Adv (2022) 8 pp. eadd4187-eadd4187 [ DOI: doi:10.1126/sciadv.add4187 Pubmed: 36490350 ]

Sample:

Unconventional myosin-va (212 kDa, Protein from Mus musculus)
Myosin va and calmodulin complex (630 kDa, Complex from Mus musculus)
Calmodulin-1 (16 kDa, Protein from Mus musculus)

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EMDB [4]

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