Cryo-EM structure of the EfPiwi (N959K)-piRNA-target ternary complex
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7yfq
Q-score: 0.435
Li Z, Li Z, Zhang Y, Zhou L, Xu Q, Li L, Zeng L, Xue J, Niu H, Zhong J, Yu Q, Li D, Gui M, Huang Y, Tu S, Zhang Z, Song CQ, Wu J, Shen EZ
Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01287-6 Pubmed: 38658622 ]
- Efpiwi(n959k)-pirna-16nt target (Complex)
- Rna (Complex)
- Pirna (7 kDa, RNA from Homo sapiens)
- Efpiwi(n959k) (Complex from Ephydatia fluviatilis)
- Magnesium ion (24 Da, Ligand)
- Piwi (92 kDa, Protein from Ephydatia fluviatilis)
- Rna (5'-r(*up*cp*cp*ap*up*gp*up*up*gp*ap*up*gp*gp*up*ap*a)-3') (5 kDa, RNA from Homo sapiens)
Cryo-EM structure of Hili in complex with piRNA
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7yfx
Q-score: 0.425
Li Z, Li Z, Zhang Y, Zhou L, Xu Q, Li L, Zeng L, Xue J, Niu H, Zhong J, Yu Q, Li D, Gui M, Huang Y, Tu S, Zhang Z, Song CQ, Wu J, Shen EZ
Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01287-6 Pubmed: 38658622 ]
- Hili-pirna (Complex)
- Pirna (8 kDa, RNA from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Pirna (Complex)
- Piwi-like protein 2 (114 kDa, Protein from Homo sapiens)
- Hili (Complex from Homo sapiens)
Cryo-EM structure of the Mili-piRNA- target ternary complex
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7yfy
Q-score: 0.406
Li Z, Li Z, Zhang Y, Zhou L, Xu Q, Li L, Zeng L, Xue J, Niu H, Zhong J, Yu Q, Li D, Gui M, Huang Y, Tu S, Zhang Z, Song CQ, Wu J, Shen EZ
Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01287-6 Pubmed: 38658622 ]
- Mili-pirna-15nt target (Complex)
- Rna (Complex)
- Piwi-like protein 2 (91 kDa, Protein from Mus musculus)
- Rna (5'-r(p*cp*cp*ap*up*gp*up*up*gp*ap*up*gp*gp*up*ap*a)-3') (4 kDa, RNA from Homo sapiens)
- Mili (Complex from Mus musculus)
- Pirna (8 kDa, RNA from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
Cryo-EM structure of the EfPiwi(N959K) in complex with piRNA
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7yg6
Q-score: 0.399
Li Z, Li Z, Zhang Y, Zhou L, Xu Q, Li L, Zeng L, Xue J, Niu H, Zhong J, Yu Q, Li D, Gui M, Huang Y, Tu S, Zhang Z, Song CQ, Wu J, Shen EZ
Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01287-6 Pubmed: 38658622 ]
- Pirna (7 kDa, RNA from Homo sapiens)
- Efpiwi(n959k) (Complex from Ephydatia fluviatilis)
- Magnesium ion (24 Da, Ligand)
- Piwi (92 kDa, Protein from Ephydatia fluviatilis)
- Pirna (Complex)
- Efpiwi(n959k)-pirna (Complex)
Cryo-EM structure of the Mili in complex with piRNA
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7ygn
Q-score: 0.5
Li Z, Li Z, Zhang Y, Zhou L, Xu Q, Li L, Zeng L, Xue J, Niu H, Zhong J, Yu Q, Li D, Gui M, Huang Y, Tu S, Zhang Z, Song CQ, Wu J, Shen EZ
Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01287-6 Pubmed: 38658622 ]
- Piwi-like protein 2 (91 kDa, Protein from Mus musculus)
- Mili-pirna (Complex)
- Mili (Complex from Mus musculus)
- Pirna (8 kDa, RNA from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Pirna (Complex)
Cryo-EM structure of broadly neutralizing V2-apex-targeting antibody J033 in complex with HIV-1 Env
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 7n28
Q-score: 0.385
Gao N, Gai Y, Meng L, Wang C, Wang W, Li X, Gu T, Louder MK, Doria-Rose NA, Wiehe K, Nazzari AF, Olia AS, Gorman J, Rawi R, Wu W, Smith C, Khant H, de Val N, Yu B, Luo J, Niu H, Tsybovsky Y, Liao H, Kepler TB, Kwong PD, Mascola JR, Qin C, Zhou T, Yu X, Gao F
Adv Sci (2022) 9 pp. e2200063-e2200063 [ DOI: doi:10.1002/advs.202200063 Pubmed: 35319830 ]
- Phosphate ion (94 Da, Ligand)
- A complex of hiv-1 env with antibodies 3bnc117 and j033 (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 3bnc117 antibody heavy chain (24 kDa, Protein from Homo sapiens)
- 3bnc117 antibody light chain (23 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp120 (54 kDa, Protein from Human immunodeficiency virus 1)
- J033 antibody heavy chain (24 kDa, Protein from Macaca mulatta)
- J033 antibody light chain (23 kDa, Protein from Macaca mulatta)
- Envelope glycoprotein gp41 (19 kDa, Protein from Human immunodeficiency virus 1)
- Alpha-d-mannopyranose (180 Da, Ligand)
Cryo-EM structure of broadly neutralizing V2-apex-targeting antibody J038 in complex with HIV-1 Env
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7mxd
Q-score: 0.47
Gao N, Gai Y, Meng L, Wang C, Wang W, Li X, Gu T, Louder MK, Doria-Rose NA, Wiehe K, Nazzari AF, Olia AS, Gorman J, Rawi R, Wu W, Smith C, Khant H, de Val N, Yu B, Luo J, Niu H, Tsybovsky Y, Liao H, Kepler TB, Kwong PD, Mascola JR, Qin C, Zhou T, Yu X, Gao F
Adv Sci (2022) 9 pp. e2200063-e2200063 [ DOI: doi:10.1002/advs.202200063 Pubmed: 35319830 ]
- Phosphate ion (94 Da, Ligand)
- J038 antibody heavy chain (24 kDa, Protein from Macaca mulatta)
- J038 antibody light chain (23 kDa, Protein from Macaca mulatta)
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- 3bnc117 antibody heavy chain (24 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 3bnc117 antibody light chain (23 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp120 (54 kDa, Protein from Human immunodeficiency virus 1)
- A complex of hiv-1 env with antibodies 3bnc117 and j038 (Complex from Homo sapiens)