Human Slo1 - human LRRC26 in presence of EDTA - GR masked
Resolution: 3.13 Å
EM Method: Single-particle
Fitted PDBs: 8vav
Q-score: 0.437
To Be Published
- Calcium-activated potassium channel subunit alpha-1 (119 kDa, Protein from Homo sapiens)
- Hetero-octameric complex of hslo1 (bk) channel and hlrrc26 subunits (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Digitonin (1 kDa, Ligand)
- Potassium ion (39 Da, Ligand)
- Leucine-rich repeat-containing protein 26 (35 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
Structure of human Slo1 and human LRRC26 in EDTA - LRRD masked
Resolution: 2.82 Å
EM Method: Single-particle
Fitted PDBs: 8vaz
Q-score: 0.504
Pal K, Kallure GS, Chowdhury S
To Be Published
- Calcium-activated potassium channel subunit alpha-1 (119 kDa, Protein from Homo sapiens)
- Potassium ion (39 Da, Ligand)
- Hetero-octameric (4:4) complex of human slo1 and human lrrc26 (Complex from Homo sapiens)
- Leucine-rich repeat-containing protein 26 (35 kDa, Protein from Homo sapiens)
F315A mutant of human Slo1 in presence of EDTA - resting VSD
Resolution: 2.43 Å
EM Method: Single-particle
Fitted PDBs: 8v60
Q-score: 0.575
To Be Published
- Calcium-activated potassium channel subunit alpha-1 (119 kDa, Protein from Homo sapiens)
- Digitonin (1 kDa, Ligand)
- Potassium ion (39 Da, Ligand)
- F315a mutant of human slo1 in detergent micelles (Complex from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Water (18 Da, Ligand)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
R207A mutant of human Slo1 in presence of EDTA - activated VSD
Resolution: 2.72 Å
EM Method: Single-particle
Fitted PDBs: 8v63
Q-score: 0.525
Pal K, Kallure GS, Chowdhury S
To Be Published
- Calcium-activated potassium channel subunit alpha-1 (119 kDa, Protein from Homo sapiens)
- Digitonin (1 kDa, Ligand)
- Potassium ion (39 Da, Ligand)
- Slo1 channel mutant r207a in presence of edta with an activated vsd (Complex from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Water (18 Da, Ligand)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
RCK1-RCK2 double mutant of human Slo1 in presence of EDTA - resting VSD
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8v64
Q-score: 0.534
Pal K, Kallure GS, Chowdhury S
To Be Published
- Digitonin (1 kDa, Ligand)
- Calcium-activated potassium channel subunit alpha-1 (119 kDa, Protein from Homo sapiens)
- Potassium ion (39 Da, Ligand)
- Human slo1 channel rck1 rck2 site double mutant in present of edta and in digitonin micelles (Complex from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Water (18 Da, Ligand)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
A complex structure of arrestin-2 bound to neurotensin receptor 1
Resolution: 4.9 Å
EM Method: Single-particle
Fitted PDBs: 6pwc
Q-score: 0.23
Yin W, Li Z, Jin M, Yin YL, de Waal PW, Pal K, Yin Y, Gao X, He Y, Gao J, Wang X, Zhang Y, Zhou H, Melcher K, Jiang Y, Cong Y, Edward Zhou X, Yu X, Eric Xu H
Cell Res (2019) 29 pp. 971-983 [ DOI: doi:10.1038/s41422-019-0256-2 Pubmed: 31776446 ]
- Neurotensin peptide (819 Da, Protein from synthetic construct)
- Beta-arrestin-1 (44 kDa, Protein from Homo sapiens)
- Fusion complex of bril-ntsr1-beta-arrestin1-fab30 (Complex from Homo sapiens)
- Fab30 light chain (23 kDa, Protein from synthetic construct)
- Fab30 heavy chain (25 kDa, Protein from synthetic construct)
- Neurotensin receptor type 1 (41 kDa, Protein from Homo sapiens)