CryoEM of PreP prepared via Chameleon
Liang WG, Wijaya J, Wei H, Noble AJ, Mancl JM, Mo S, Lee D, Lin King JV, Pan M, Liu C, Koehler CM, Zhao M, Potter CS, Carragher B, Li S, Tang WJ
Nat Commun (2022) 13 [ DOI: 10.1038/s41467-022-29322-4 Pubmed: 35383169 ]
Image sets:
- PreP half particles
- Apo-PreP micrographs
- Citrate synthase presequence bound PreP
- Amyloid beta bound PreP
CryoET of presequence protease single particle
Liang WG, Wijaya J, Wei H, Noble AJ, Mancl JM, Mo S, Lee D, Lin King JV, Pan M, Liu C, Koehler CM, Zhao M, Potter CS, Carragher B, Li S, Tang WJ
Nat Commun (2022) 13 [ DOI: 10.1038/s41467-022-29322-4 Pubmed: 35383169 ]
Image sets:
CryoET of presequence protease single particle
Liang WG, Wijaya J, Wei H, Noble AJ, Mancl JM, Mo S, Lee D, Lin King JV, Pan M, Liu C, Koehler CM, Zhao M, Potter CS, Carragher B, Li S, Tang WJ
Nat Commun (2022) 13 pp. 1833-1833 [ Pubmed: 35383169 DOI: doi:10.1038/s41467-022-29322-4 ]
- Human presequence protease (117 kDa, Complex from Escherichia phage EcSzw-2)
CryoEM structure of human presequence protease in partial open state 1
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 6xos
Q-score: 0.405
Liang WG, Wijaya J, Wei H, Noble AJ, Mancl JM, Mo S, Lee D, Lin King JV, Pan M, Liu C, Koehler CM, Zhao M, Potter CS, Carragher B, Li S, Tang WJ
Nat Commun (2022) 13 pp. 1833-1833 [ Pubmed: 35383169 DOI: doi:10.1038/s41467-022-29322-4 ]
CryoEM structure of human presequence protease in partial open state 2
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 6xot
Q-score: 0.315
Liang WG, Wijaya J, Wei H, Noble AJ, Mancl JM, Mo S, Lee D, Lin King JV, Pan M, Liu C, Koehler CM, Zhao M, Potter CS, Carragher B, Li S, Tang WJ
Nat Commun (2022) 13 pp. 1833-1833 [ Pubmed: 35383169 DOI: doi:10.1038/s41467-022-29322-4 ]
CryoEM structure of human presequence protease in open state
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6xou
Q-score: 0.333
Liang WG, Wijaya J, Wei H, Noble AJ, Mancl JM, Mo S, Lee D, Lin King JV, Pan M, Liu C, Koehler CM, Zhao M, Potter CS, Carragher B, Li S, Tang WJ
Nat Commun (2022) 13 pp. 1833-1833 [ Pubmed: 35383169 DOI: doi:10.1038/s41467-022-29322-4 ]
CryoEM structure of human presequence protease in partial closed state 1
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6xov
Q-score: 0.468
Liang WG, Wijaya J, Wei H, Noble AJ, Mancl JM, Mo S, Lee D, Lin King JV, Pan M, Liu C, Koehler CM, Zhao M, Potter CS, Carragher B, Li S, Tang WJ
Nat Commun (2022) 13 pp. 1833-1833 [ Pubmed: 35383169 DOI: doi:10.1038/s41467-022-29322-4 ]
- Amyloid-beta precursor protein (273 Da, Protein from Homo sapiens)
- Amyloid-beta precursor protein (4 kDa, Protein from Homo sapiens)
- Presequence protease, mitochondrial (114 kDa, Protein from Homo sapiens)
- Cryoem map of human presequence protease in partial close state 1 (Complex from Homo sapiens)