Cryo-EM structure of the human TRPC1/C4 heteromer
Resolution: 3.04 Å
EM Method: Single-particle
Fitted PDBs: 8wpl
Q-score: 0.504
Won J, Kim J, Kim J, Ko J, Park CH, Jeong B, Lee SE, Jeong H, Kim SH, Park H, So I, Lee HH
Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01408-1 Pubmed: 39478185 ]
- Structure of a trp channel complex, apo state (Complex from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Short transient receptor potential channel 4 (105 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Short transient receptor potential channel 1 (91 kDa, Protein from Homo sapiens)
- 2-(hexadecanoyloxy)-1-[(phosphonooxy)methyl]ethyl hexadecanoate (648 Da, Ligand)
Cryo-EM structure of the human TRPC1/C4 heteromer in complex with Pico145
Resolution: 3.43 Å
EM Method: Single-particle
Fitted PDBs: 8wpm
Q-score: 0.442
Won J, Kim J, Kim J, Ko J, Park CH, Jeong B, Lee SE, Jeong H, Kim SH, Park H, So I, Lee HH
Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01408-1 Pubmed: 39478185 ]
- Structure of a trp channel complex, apo state (Complex from Homo sapiens)
- Short transient receptor potential channel 4 (105 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Short transient receptor potential channel 1 (91 kDa, Protein from Homo sapiens)
- 7-[(4-chlorophenyl)methyl]-3-methyl-1-(3-oxidanylpropyl)-8-[3-(trifluoromethyloxy)phenoxy]purine-2,6-dione (524 Da, Ligand)
- Zinc ion (65 Da, Ligand)
Cryo-EM structure of the human TRPC4 in lipid nanodiscs
Resolution: 2.82 Å
EM Method: Single-particle
Fitted PDBs: 8wpn
Q-score: 0.567
Won J, Kim J, Kim J, Ko J, Park CH, Jeong B, Lee SE, Jeong H, Kim SH, Park H, So I, Lee HH
Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01408-1 Pubmed: 39478185 ]
- 2-(hexadecanoyloxy)-1-[(phosphonooxy)methyl]ethyl hexadecanoate (648 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Short transient receptor potential channel 4 (105 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Structure of a trp channel (Complex from Homo sapiens)
- Zinc ion (65 Da, Ligand)
Human Consensus Olfactory Receptor OR52c in Complex with Octanoic Acid (OCA) and G Protein
Resolution: 2.97 Å
EM Method: Single-particle
Fitted PDBs: 8hti
Q-score: 0.583
Choi C, Bae J, Kim S, Lee S, Kang H, Kim J, Bang I, Kim K, Huh WK, Seok C, Park H, Im W, Choi HJ
Nat Commun (2023) 14 pp. 8105-8105 [ Pubmed: 38062020 DOI: doi:10.1038/s41467-023-43983-9 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
- Consensus olfactory receptor or52c (36 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Complex of consensus olfactory receptor or52c in complex with octanoic acid, g protein and nanobody 35 (nb35) (140 kDa, Complex from Homo sapiens)
- Octanoic acid (caprylic acid) (144 Da, Ligand)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (45 kDa, Protein from Homo sapiens)
- Nanobody 35 (15 kDa, Protein from Lama glama)
Human Consensus Olfactory Receptor OR52c in apo state, OR52c-bRIL
Resolution: 3.66 Å
EM Method: Single-particle
Fitted PDBs: 8j46
Q-score: 0.365
Human Consensus Olfactory Receptor OR52c in apo state, OR52c only
Activity optimized supercomplex state1
Resolution: 5.0 Å
EM Method: Single-particle
Fitted PDBs: 7dgq
Q-score: 0.137
Jeon TJ, Lee SG, Yoo SH, Kim M, Song D, Ryu J, Park H, Kim DS, Hyun J, Kim HM, Ryu SE
Antioxid Redox Signal (2022) [ Pubmed: 34913730 DOI: doi:10.1089/ars.2021.0114 ]
- Cytochrome c oxidase subunit 3 (29 kDa, Protein from Bos taurus)
- Cytochrome c oxidase subunit 7c, mitochondrial (7 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (20 kDa, Protein from Bos taurus)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (16 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (8 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Bos taurus)
- Flavin mononucleotide (456 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (14 kDa, Protein from Bos taurus)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (21 kDa, Protein from Bos taurus)
- Cytochrome b-c1 complex subunit rieske, mitochondrial (21 kDa, Protein from Bos taurus)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Bos taurus)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Cytochrome b-c1 complex subunit rieske, mitochondrial (7 kDa, Protein from Bos taurus)
- Cytochrome b-c1 complex subunit 10 (6 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Bos taurus)
- Cytochrome b (42 kDa, Protein from Bos taurus)
- Cytochrome b-c1 complex subunit 6, mitochondrial (10 kDa, Protein from Bos taurus)
- Ubiquinone-2 (318 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (21 kDa, Protein from Bos taurus)
- Cytochrome c oxidase subunit 2 (26 kDa, Protein from Bos taurus)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (77 kDa, Protein from Bos taurus)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (39 kDa, Protein from Bos taurus)
- Cytochrome c oxidase subunit 7a1, mitochondrial (9 kDa, Protein from Bos taurus)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Bos taurus)
- Copper (ii) ion (63 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Bos taurus)
- Cytochrome b-c1 complex subunit 8 (9 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (36 kDa, Protein from Bos taurus)
- Acyl carrier protein, mitochondrial (9 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from Bos taurus)
- Cytochrome c oxidase subunit 7b, mitochondrial (9 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Bos taurus)
- Nadp nicotinamide-adenine-dinucleotide phosphate (743 Da, Ligand)
- Cytochrome c1, heme protein, mitochondrial (35 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Bos taurus)
- Heme c (618 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (14 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (26 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (14 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (8 kDa, Protein from Bos taurus)
- Nadh-ubiquinone oxidoreductase chain 4 (52 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Bos taurus)
- Cytochrome b-c1 complex subunit 2, mitochondrial (48 kDa, Protein from Bos taurus)
- Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (19 kDa, Protein from Bos taurus)
- Cytochrome b-c1 complex subunit 1, mitochondrial (52 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from Bos taurus)
- Cytochrome c oxidase subunit 5b, mitochondrial (13 kDa, Protein from Bos taurus)
- Cytochrome b-c1 complex subunit 7 (13 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (18 kDa, Protein from Bos taurus)
- Heme-a (852 Da, Ligand)
- Cytochrome c oxidase subunit 6c (8 kDa, Protein from Bos taurus)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (5 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (49 kDa, Protein from Bos taurus)
- Cytochrome c oxidase subunit 1 (57 kDa, Protein from Bos taurus)
- Cytochrome b-c1 complex subunit 9 (7 kDa, Protein from Bos taurus)
- Cytochrome c oxidase subunit 6b1 (10 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Bos taurus)
- Cytochrome c oxidase subunit 5a, mitochondrial (16 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (20 kDa, Protein from Bos taurus)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (19 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (48 kDa, Protein from Bos taurus)
- Cytochrome c oxidase subunit 6a2, mitochondrial (10 kDa, Protein from Bos taurus)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (15 kDa, Protein from Bos taurus)
- Cardiolipin (1 kDa, Ligand)
- Magnesium ion (24 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from Bos taurus)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from Bos taurus)
- Supercomplex of electron transport chain complexes (Complex from Bos taurus)
- Cytochrome c oxidase subunit 8b, mitochondrial (7 kDa, Protein from Bos taurus)