TAS2R14 receptor bound to flufenamic acid and gustducin
Peri L, Matzov D, Huxley DR, Rainish A, Fierro F, Sapir L, Pfeiffer T, Waterloo L, Hubner H, Peleg Y, Gmeiner P, McCormick PJ, Weikert D, Niv MY, Shalev-Benami M
Nat Commun (2024) 15 pp. 9991-9991 [ DOI: doi:10.1038/s41467-024-54157-6 Pubmed: 39557861 ]
TAS2R14 receptor bound to flufenamic acid and gustducin
Peri L, Matzov D, Huxley DR, Rainish A, Fierro F, Sapir L, Pfeiffer T, Waterloo L, Hubner H, Peleg Y, Gmeiner P, McCormick PJ, Weikert D, Niv MY, Shalev-Benami M
Nat Commun (2024) 15 pp. 9991-9991 [ DOI: doi:10.1038/s41467-024-54157-6 Pubmed: 39557861 ]
TAS2R14 receptor bound to flufenamic acid and gustducin
Peri L, Matzov D, Huxley DR, Rainish A, Fierro F, Sapir L, Pfeiffer T, Waterloo L, Hubner H, Peleg Y, Gmeiner P, McCormick PJ, Weikert D, Niv MY, Shalev-Benami M
Nat Commun (2024) 15 pp. 9991-9991 [ DOI: doi:10.1038/s41467-024-54157-6 Pubmed: 39557861 ]
Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 8rql
Q-score: 0.48
Peri L, Matzov D, Huxley DR, Rainish A, Fierro F, Sapir L, Pfeiffer T, Waterloo L, Hubner H, Peleg Y, Gmeiner P, McCormick PJ, Weikert D, Niv MY, Shalev-Benami M
Nat Commun (2024) 15 pp. 9991-9991 [ DOI: doi:10.1038/s41467-024-54157-6 Pubmed: 39557861 ]
- Scfv16 (27 kDa, Protein from Mus musculoides)
- Taste receptor type 2 member 14 (36 kDa, Protein from Homo sapiens)
- Human taste receptor type 2 member 14 in complex with g-proteins (118 MDa, Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(t) subunit alpha-3 (25 kDa, Protein from Homo sapiens)
- Human taste receptor type 2 member 14 in complex with g-proteins (Complex from Homo sapiens)
- 2-[[3-(trifluoromethyl)phenyl]amino] benzoic acid (281 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Scfv16 (antibody) (Complex from Mus musculoides)
Cryo-EM structure of Bestrhodopsin (rhodopsin-rhodopsin-bestrophin) complex
Resolution: 3.21 Å
EM Method: Single-particle
Fitted PDBs: 7pl9
Q-score: 0.458
Rozenberg A, Kaczmarczyk I, Matzov D, Vierock J, Nagata T, Sugiura M, Katayama K, Kawasaki Y, Konno M, Nagasaka Y, Aoyama M, Das I, Pahima E, Church J, Adam S, Borin VA, Chazan A, Augustin S, Wietek J, Dine J, Peleg Y, Kawanabe A, Fujiwara Y, Yizhar O, Sheves M, Schapiro I, Furutani Y, Kandori H, Inoue K, Hegemann P, Beja O, Shalev-Benami M
Nat Struct Mol Biol (2022) 29 pp. 592-603 [ DOI: doi:10.1038/s41594-022-00783-x Pubmed: 35710843 ]
- Rhodopsin (134 kDa, Protein from Phaeocystis)
- Retinal (284 Da, Ligand)
- Rhodopsin (670 kDa, Complex from Phaeocystis antarctica)
Melanocortin receptor 4 (MC4R) Gs protein complex
Resolution: 2.97 Å
EM Method: Single-particle
Fitted PDBs: 7aue
Q-score: 0.592
Israeli H, Degtjarik O, Fierro F, Chunilal V, Gill AK, Roth NJ, Botta J, Prabahar V, Peleg Y, Chan LF, Ben-Zvi D, McCormick PJ, Niv MY, Shalev-Benami M
Science (2021) 372 pp. 808-814 [ DOI: doi:10.1126/science.abf7958 Pubmed: 33858992 ]
- Water (18 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
- Aminoserine (Complex from synthetic construct)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (43 kDa, Protein from Homo sapiens)
- Scfv16 (27 kDa, Protein from Mus musculus)
- Aminoserine (1 kDa, Protein from synthetic construct)
- Melanocortine 4 (mc4r) - galphas protein comlex (Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Scfv16 (Complex from Mus musculus)
- Melanocortin receptor 4 (38 kDa, Protein from Homo sapiens)
- Melanocortine 4 (mc4r) - galphas protein comlex (Complex from Homo sapiens)
Structure of Mycobacterium tuberculosis Fatty Acid Synthase - I
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6gjc
Q-score: 0.443
Elad N, Baron S, Peleg Y, Albeck S, Grunwald J, Raviv G, Shakked Z, Zimhony O, Diskin R
Nat Commun (2018) 9 pp. 3886-3886 [ Pubmed: 30250274 DOI: doi:10.1038/s41467-018-06440-6 ]
- Flavin mononucleotide (456 Da, Ligand)
- Fatty acid synthase (329 kDa, Protein from Mycobacterium tuberculosis)
- Fatty acid synthase - i (Complex from Mycobacterium tuberculosis)