Structure of full-length CD20 in complex with Rituximab Fab
Resolution: 3.69 Å
EM Method: Single-particle
Fitted PDBs: 6y90
Q-score: 0.365
Kumar A, Planchais C, Fronzes R, Mouquet H, Reyes N
Science (2020) 369 pp. 793-799 [ DOI: doi:10.1126/science.abb8008 Pubmed: 32792392 ]
- Rituximab fab (Complex from Mus musculus)
- Rituximab fab light chain (23 kDa, Protein from Mus musculus)
- Full-length human cd20 (Complex from Homo sapiens)
- Rituximab fab heavy chain (23 kDa, Protein from Mus musculus)
- Pentadecane (212 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Full-length human antigen cd20 in complex with rituximab fab (Complex)
- B-lymphocyte antigen cd20 (19 kDa, Protein from Homo sapiens)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
Structure of full-length CD20 in complex with Ofatumumab Fab
Resolution: 4.73 Å
EM Method: Single-particle
Fitted PDBs: 6y92
Q-score: 0.302
Kumar A, Planchais C, Fronzes R, Mouquet H, Reyes N
Science (2020) 369 pp. 793-799 [ DOI: doi:10.1126/science.abb8008 Pubmed: 32792392 ]
- B-lymphocyte antigen cd20 (19 kDa, Protein from Homo sapiens)
- Full-length human cd20 (Complex from Homo sapiens)
- Ofatumumab fab light chain (23 kDa, Protein from Homo sapiens)
- Ofatumumab fab heavy chain (23 kDa, Protein from Homo sapiens)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Full-length human antigen cd20 in complex with ofatumumab fab (Complex)
- Ofatumumab fab (Complex from Homo sapiens)
Structure of full-length CD20 in complex with Obinutuzumab Fab
Resolution: 4.33 Å
EM Method: Single-particle
Fitted PDBs: 6y97
Q-score: 0.257
Kumar A, Planchais C, Fronzes R, Mouquet H, Reyes N
Science (2020) 369 pp. 793-799 [ DOI: doi:10.1126/science.abb8008 Pubmed: 32792392 ]
- B-lymphocyte antigen cd20 (18 kDa, Protein from Homo sapiens)
- Full-length human cd20 (Cellular component from Homo sapiens)
- Full-length human antigen cd20 in complex with obinutuzumab fab (Cell from Homo sapiens)
- Obinutuzumab fab (Cellular component from Homo sapiens)
- Obinutuzumab fab light chain (11 kDa, Protein from Homo sapiens)
- Obinutuzumab fab heavy chain (12 kDa, Protein from Homo sapiens)
Structure of full-length CD20 in complex with Ofatumumab Fab
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6y9a
Q-score: 0.205
Kumar A, Planchais C, Fronzes R, Mouquet H, Reyes N
Science (2020) 369 pp. 793-799 [ DOI: doi:10.1126/science.abb8008 Pubmed: 32792392 ]
- Obinutuzumab fab heavy chain (23 kDa, Protein from Homo sapiens)
- B-lymphocyte antigen cd20 (18 kDa, Protein from Homo sapiens)
- Full-length human cd20 (Complex from Homo sapiens)
- Obinutuzumab fab (Complex from Homo sapiens)
- Full-length human antigen cd20 in complex with obinutuzumab (Complex)
- Obinutuzumab fab light chain (23 kDa, Protein from Homo sapiens)