Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7s6i
Q-score: 0.514
Torres JL, Ozorowski G, Andreano E, Liu H, Copps J, Piccini G, Donnici L, Conti M, Planchais C, Planas D, Manganaro N, Pantano E, Paciello I, Pileri P, Bruel T, Montomoli E, Mouquet H, Schwartz O, Sala C, De Francesco R, Wilson IA, Rappuoli R, Ward AB
PNAS (2022) 119 pp. e2120976119-e2120976119 [ Pubmed: 35549549 DOI: doi:10.1073/pnas.2120976119 ]
J08 fragment antigen binding in complex with SARS-CoV-2-6P-Mut7 S protein (conformation 3)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7s6j
Q-score: 0.376
Torres JL, Ozorowski G, Andreano E, Liu H, Copps J, Piccini G, Donnici L, Conti M, Planchais C, Planas D, Manganaro N, Pantano E, Paciello I, Pileri P, Bruel T, Montomoli E, Mouquet H, Schwartz O, Sala C, De Francesco R, Wilson IA, Rappuoli R, Ward AB
PNAS (2022) 119 pp. e2120976119-e2120976119 [ Pubmed: 35549549 DOI: doi:10.1073/pnas.2120976119 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- J08 fragment antigen binding heavy chain variable domain (13 kDa, Protein from Homo sapiens)
- J08 fragment antigen binding in complex with sars-2-cov-6p-mut2 s protein (690 kDa, Complex)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- J08 fragment antigen binding light chain variable domain (11 kDa, Protein from Homo sapiens)
J08 fragment antigen binding in complex with SARS-CoV-2-6P-Mut2 S protein (conformation 2)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7s6k
Q-score: 0.416
Torres JL, Ozorowski G, Andreano E, Liu H, Copps J, Piccini G, Donnici L, Conti M, Planchais C, Planas D, Manganaro N, Pantano E, Paciello I, Pileri P, Bruel T, Montomoli E, Mouquet H, Schwartz O, Sala C, De Francesco R, Wilson IA, Rappuoli R, Ward AB
PNAS (2022) 119 pp. e2120976119-e2120976119 [ Pubmed: 35549549 DOI: doi:10.1073/pnas.2120976119 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- J08 fragment antigen binding in complex with sars-2-cov-6p-mut2 s protein (690 kDa, Complex)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- J08 fragment antigen binding light chain variable domain (11 kDa, Protein from Homo sapiens)
- J08 fragment antigen binding heavy chain variable domain (13 kDa, Protein from Homo sapiens)
J08 fragment antigen binding in complex with SARS-CoV-2-6P-Mut7 S protein (conformation 3)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7s6l
Q-score: 0.299
Torres JL, Ozorowski G, Andreano E, Liu H, Copps J, Piccini G, Donnici L, Conti M, Planchais C, Planas D, Manganaro N, Pantano E, Paciello I, Pileri P, Bruel T, Montomoli E, Mouquet H, Schwartz O, Sala C, De Francesco R, Wilson IA, Rappuoli R, Ward AB
PNAS (2022) 119 pp. e2120976119-e2120976119 [ Pubmed: 35549549 DOI: doi:10.1073/pnas.2120976119 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- J08 fragment antigen binding in complex with sars-2-cov-6p-mut7 s protein (590 kDa, Complex)
- J08 fragment antigen binding light chain variable domain (11 kDa, Protein from Homo sapiens)
- J08 fragment antigen binding heavy chain variable domain (13 kDa, Protein from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Structure of full-length CD20 in complex with Rituximab Fab
Resolution: 3.69 Å
EM Method: Single-particle
Fitted PDBs: 6y90
Q-score: 0.365
Kumar A, Planchais C, Fronzes R, Mouquet H, Reyes N
Science (2020) 369 pp. 793-799 [ DOI: doi:10.1126/science.abb8008 Pubmed: 32792392 ]
- Rituximab fab (Complex from Mus musculus)
- Rituximab fab light chain (23 kDa, Protein from Mus musculus)
- Full-length human cd20 (Complex from Homo sapiens)
- Rituximab fab heavy chain (23 kDa, Protein from Mus musculus)
- Pentadecane (212 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Full-length human antigen cd20 in complex with rituximab fab (Complex)
- B-lymphocyte antigen cd20 (19 kDa, Protein from Homo sapiens)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
Structure of full-length CD20 in complex with Obinutuzumab Fab
Resolution: 4.33 Å
EM Method: Single-particle
Fitted PDBs: 6y97
Q-score: 0.257
Kumar A, Planchais C, Fronzes R, Mouquet H, Reyes N
Science (2020) 369 pp. 793-799 [ DOI: doi:10.1126/science.abb8008 Pubmed: 32792392 ]
- B-lymphocyte antigen cd20 (18 kDa, Protein from Homo sapiens)
- Full-length human cd20 (Cellular component from Homo sapiens)
- Full-length human antigen cd20 in complex with obinutuzumab fab (Cell from Homo sapiens)
- Obinutuzumab fab (Cellular component from Homo sapiens)
- Obinutuzumab fab light chain (11 kDa, Protein from Homo sapiens)
- Obinutuzumab fab heavy chain (12 kDa, Protein from Homo sapiens)
Structure of full-length CD20 in complex with Ofatumumab Fab
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6y9a
Q-score: 0.205
Kumar A, Planchais C, Fronzes R, Mouquet H, Reyes N
Science (2020) 369 pp. 793-799 [ DOI: doi:10.1126/science.abb8008 Pubmed: 32792392 ]
- Obinutuzumab fab heavy chain (23 kDa, Protein from Homo sapiens)
- B-lymphocyte antigen cd20 (18 kDa, Protein from Homo sapiens)
- Full-length human cd20 (Complex from Homo sapiens)
- Obinutuzumab fab (Complex from Homo sapiens)
- Full-length human antigen cd20 in complex with obinutuzumab (Complex)
- Obinutuzumab fab light chain (23 kDa, Protein from Homo sapiens)