SARS-CoV-2 Omicron variant spike in complex with Fab XGv264
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7wti
Q-score: 0.322
Wang L, Fu W, Bao L, Jia Z, Zhang Y, Zhou Y, Wu W, Wu J, Zhang Q, Gao Y, Wang K, Wang Q, Qin C, Wang X
Cell Res (2022) 32 pp. 691-694 [ DOI: doi:10.1038/s41422-022-00677-z Pubmed: 35672388 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 omicron variant spike (Complex from Homo sapiens)
- Heavy chain of xgv264 (13 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron variant spike in complex with fab xgv264 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Fab xgv264 (Complex)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Light chain of xgv264 (11 kDa, Protein from Homo sapiens)
SARS-CoV-2 Omicron variant spike in complex with Fab XGv051
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7wtf
Q-score: 0.318
Wang L, Fu W, Bao L, Jia Z, Zhang Y, Zhou Y, Wu W, Wu J, Zhang Q, Gao Y, Wang K, Wang Q, Qin C, Wang X
Cell Res (2022) 32 pp. 691-694 [ DOI: doi:10.1038/s41422-022-00677-z Pubmed: 35672388 ]
- Heavy chain of xgv051 (13 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Fab xgv051 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Light chain of xgv051 (11 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron variant spike in complex with fab xgv051 (Complex from Homo sapiens)
- Sars-cov-2 omicron variant spike (Complex)
- Spike glycoprotein (127 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 Omicron variant spike in complex with Fab XGv286
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7wtk
Q-score: 0.355
Wang L, Fu W, Bao L, Jia Z, Zhang Y, Zhou Y, Wu W, Wu J, Zhang Q, Gao Y, Wang K, Wang Q, Qin C, Wang X
Cell Res (2022) 32 pp. 691-694 [ DOI: doi:10.1038/s41422-022-00677-z Pubmed: 35672388 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 omicron variant spike (Complex from Homo sapiens)
- Light chain of xgv286 (11 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron variant spike in complex with fab xgv286 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (127 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Fab xgv286 (Complex)
- Heavy chain of xgv286 (12 kDa, Protein from Homo sapiens)
SARS-CoV-2 Omicron variant spike protein in complex with Fab XGv282
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7we7
Q-score: 0.315
Wang K, Jia Z, Bao L, Wang L, Cao L, Chi H, Hu Y, Li Q, Zhou Y, Jiang Y, Zhu Q, Deng Y, Liu P, Wang N, Wang L, Liu M, Li Y, Zhu B, Fan K, Fu W, Yang P, Pei X, Cui Z, Qin L, Ge P, Wu J, Liu S, Chen Y, Huang W, Wang Q, Qin CF, Wang Y, Qin C, Wang X
Nature (2022) 603 pp. 919-925 [ Pubmed: 35090164 DOI: doi:10.1038/s41586-022-04466-x ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- The light chain of fab 282 (11 kDa, Protein from Homo sapiens)
- Heavy chain of fab 282 (13 kDa, Protein from Homo sapiens)
- Fab 282 (Complex from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 omicron mutation spike protein (Complex)
- Sars-cov-2 omicron mutation spike protein in complex with fab 265 (Complex from Homo sapiens)
SARS-CoV-2 Omicron variant spike protein in complex with Fab XGv265
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7we8
Q-score: 0.363
Wang K, Jia Z, Bao L, Wang L, Cao L, Chi H, Hu Y, Li Q, Zhou Y, Jiang Y, Zhu Q, Deng Y, Liu P, Wang N, Wang L, Liu M, Li Y, Zhu B, Fan K, Fu W, Yang P, Pei X, Cui Z, Qin L, Ge P, Wu J, Liu S, Chen Y, Huang W, Wang Q, Qin CF, Wang Y, Qin C, Wang X
Nature (2022) 603 pp. 919-925 [ Pubmed: 35090164 DOI: doi:10.1038/s41586-022-04466-x ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Fab 265 (Complex)
- Sars-cov-2 omicron mutation spike protein in complex with fab 265 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Light chain of fab 265 (11 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron mutation spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Heavy chain of fab 265 (13 kDa, Protein from Homo sapiens)
SARS-CoV-2 Omicron variant spike protein in complex with Fab XGv289
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7we9
Q-score: 0.349
Wang K, Jia Z, Bao L, Wang L, Cao L, Chi H, Hu Y, Li Q, Zhou Y, Jiang Y, Zhu Q, Deng Y, Liu P, Wang N, Wang L, Liu M, Li Y, Zhu B, Fan K, Fu W, Yang P, Pei X, Cui Z, Qin L, Ge P, Wu J, Liu S, Chen Y, Huang W, Wang Q, Qin CF, Wang Y, Qin C, Wang X
Nature (2022) 603 pp. 919-925 [ Pubmed: 35090164 DOI: doi:10.1038/s41586-022-04466-x ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- The heavy chain of fab xgv289 (13 kDa, Protein from Homo sapiens)
- Fab 289 (Complex)
- Sars-cov-2 omicron mutation spike protein in complex with fab 265 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 omicron mutation spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- The light chain of fab xgv289 (11 kDa, Protein from Homo sapiens)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7wea
Q-score: 0.421
Wang K, Jia Z, Bao L, Wang L, Cao L, Chi H, Hu Y, Li Q, Zhou Y, Jiang Y, Zhu Q, Deng Y, Liu P, Wang N, Wang L, Liu M, Li Y, Zhu B, Fan K, Fu W, Yang P, Pei X, Cui Z, Qin L, Ge P, Wu J, Liu S, Chen Y, Huang W, Wang Q, Qin CF, Wang Y, Qin C, Wang X
Nature (2022) 603 pp. 919-925 [ Pubmed: 35090164 DOI: doi:10.1038/s41586-022-04466-x ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- The heavy chain of fab xgv347 (13 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron mutation spike protein in complex with fab 265 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- The light chain of fab xgv347 (11 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron mutation spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Fab xgv347 (Complex)
SARS-CoV-2 Omicron variant spike protein with two XGv347 binding to two open state RBDs
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7web
Q-score: 0.337
Wang K, Jia Z, Bao L, Wang L, Cao L, Chi H, Hu Y, Li Q, Zhou Y, Jiang Y, Zhu Q, Deng Y, Liu P, Wang N, Wang L, Liu M, Li Y, Zhu B, Fan K, Fu W, Yang P, Pei X, Cui Z, Qin L, Ge P, Wu J, Liu S, Chen Y, Huang W, Wang Q, Qin CF, Wang Y, Qin C, Wang X
Nature (2022) 603 pp. 919-925 [ Pubmed: 35090164 DOI: doi:10.1038/s41586-022-04466-x ]
- Fab 347 (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- The heavy chain of fab xgv347 (13 kDa, Protein from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- The light chain of fab xgv347 (11 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron mutation spike protein (Complex)
- Sars-cov-2 omicron mutation spike protein in complex with fab 265 (Complex from Homo sapiens)
SARS-CoV-2 Omicron variant spike protein with three XGv347 Fabs binding to three closed state RBDs
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7wec
Q-score: 0.433
Wang K, Jia Z, Bao L, Wang L, Cao L, Chi H, Hu Y, Li Q, Zhou Y, Jiang Y, Zhu Q, Deng Y, Liu P, Wang N, Wang L, Liu M, Li Y, Zhu B, Fan K, Fu W, Yang P, Pei X, Cui Z, Qin L, Ge P, Wu J, Liu S, Chen Y, Huang W, Wang Q, Qin CF, Wang Y, Qin C, Wang X
Nature (2022) 603 pp. 919-925 [ Pubmed: 35090164 DOI: doi:10.1038/s41586-022-04466-x ]
- Fab 347 (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- The heavy chain of fab xgv347 (13 kDa, Protein from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- The light chain of fab xgv347 (11 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron mutation spike protein (Complex)
- Sars-cov-2 omicron mutation spike protein in complex with fab 265 (Complex from Homo sapiens)