SLC19A3-thiamine outward structure
Resolution: 3.05 Å
EM Method: Single-particle
Fitted PDBs: 8z7s
Q-score: 0.541
SLC19A3-Pyridoxine outward structure
Resolution: 3.39 Å
EM Method: Single-particle
Fitted PDBs: 8z7t
Q-score: 0.492
Li P, Zhu Z, Wang Y, Zhang X, Yang C, Zhu Y, Zhou Z, Chao Y, Long Y, Gao Y, Liu S, Zhang L, Gao P, Qu Q
Nat Commun (2024) 15 pp. 10924-10924 [ DOI: doi:10.1038/s41467-024-55359-8 Pubmed: 39738067 ]
- 4,5-bis(hydroxymethyl)-2-methyl-pyridin-3-ol (169 Da, Ligand)
- Slc19a3 (Complex from Homo sapiens)
- Thiamine transporter 2 (55 kDa, Protein from Homo sapiens)
SLC19A3-Fedratinib outward structure
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8z7u
Q-score: 0.535
SLC19A3-Metformin outward structure
Resolution: 3.09 Å
EM Method: Single-particle
Fitted PDBs: 8z7w
Q-score: 0.533
Li P, Zhu Z, Wang Y, Zhang X, Yang C, Zhu Y, Zhou Z, Chao Y, Long Y, Gao Y, Liu S, Zhang L, Gao P, Qu Q
Nat Commun (2024) 15 pp. 10924-10924 [ DOI: doi:10.1038/s41467-024-55359-8 Pubmed: 39738067 ]
- Metformin (129 Da, Ligand)
- Slc19a3 (Complex from Homo sapiens)
- Thiamine transporter 2 (55 kDa, Protein from Homo sapiens)
SLC19A3-Thiamine inward structure
Resolution: 3.36 Å
EM Method: Single-particle
Fitted PDBs: 8z7x
Q-score: 0.443
SLC19A3-Fedratinib inward structure
Resolution: 3.02 Å
EM Method: Single-particle
Fitted PDBs: 8z7y
Q-score: 0.484
SLC19A2-Thiamine inward structure
Resolution: 3.23 Å
EM Method: Single-particle
Fitted PDBs: 8z7z
Q-score: 0.389
SLC19A2-Pyridoxine inward structure
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8z80
Q-score: 0.288
Li P, Zhu Z, Wang Y, Zhang X, Yang C, Zhu Y, Zhou Z, Chao Y, Long Y, Gao Y, Liu S, Zhang L, Gao P, Qu Q
Nat Commun (2024) 15 pp. 10924-10924 [ DOI: doi:10.1038/s41467-024-55359-8 Pubmed: 39738067 ]
- Slc19a3-thiamine complex (Complex from Homo sapiens)
- Thiamine transporter 1 (55 kDa, Protein from Homo sapiens)
- 4,5-bis(hydroxymethyl)-2-methyl-pyridin-3-ol (169 Da, Ligand)
Structure of the Epstein-Barr virus GPCR BILF1 in complex with human Gi
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7jhj
Q-score: 0.54
Tsutsumi N, Qu Q, Mavri M, Baggesen MS, Maeda S, Waghray D, Berg C, Kobilka BK, Rosenkilde MM, Skiniotis G, Garcia KC
Immunity (2021) 54 pp. 1405-1416.e7 [ Pubmed: 34216564 DOI: doi:10.1016/j.immuni.2021.06.001 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Scfv16 (30 kDa, Complex from Mus musculus)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Bilf1 (35 kDa, Protein from Epstein-Barr virus)
- Antibody fragment scfv16 (27 kDa, Protein from Mus musculus)
- Bilf1-gi-scfv16 complex (Complex)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Gi heterotrimer (70 kDa, Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Bilf1 (40 kDa, Complex from Human gammaherpesvirus 4)
neurotensin receptor and arrestin2 complex
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6up7
Q-score: 0.406
Huang W, Masureel M, Qu Q, Janetzko J, Inoue A, Kato HE, Robertson MJ, Nguyen KC, Glenn JS, Skiniotis G, Kobilka BK
Nature (2020) 579 pp. 303-308 [ Pubmed: 31945771 DOI: doi:10.1038/s41586-020-1953-1 ]
- [(2r)-2-octanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate (746 Da, Ligand)
- Arg-arg-pro-tyr-ile-leu (819 Da, Protein from Homo sapiens)
- Neurotensin receptor type 1 (37 kDa, Protein from Homo sapiens)
- Unidentified peptide (783 Da, Protein from Homo sapiens)
- Beta-arrestin-1 (39 kDa, Protein from Homo sapiens)
- Ntsr_arrestin (Complex from Homo sapiens)